Results 31 to 40 of about 216,066 (287)

In-depth characterization of N-glycosylation and sialic acid content in fetal and adult fibrinogen

Research and Practice in Thrombosis and Haemostasis
Background: Fetal fibrinogen is a variant present in neonates. Blood products used in neonates are tailored for adults and do not seamlessly integrate into neonatal clots.
Tana V. Palomino, Anastasia Sheridan, David C. Muddiman, Ashley C. Brown   +3 more
doaj   +1 more source

Young girl with congenital hypo-dysfibrogenemia presenting with an acute subdural haemorrhage

Asian Journal of Internal Medicine, 2023
Fibrinogen plays a pivotal role in the coagulation cascade. Inherited fibrinogen disorders are a heterogenous group that includes lack or reduced fibrinogen levels or a qualitative disorder of fibrinogen, dysfibrinogenemia.
I. N. Walmsley, D. T. E. Wijegunaratne, S. Satheeshkumar, N. Ranasinghe   +3 more
doaj   +1 more source

Plasma Fibrinogen Level as a Biomarker of Disease Activity in Multiple Sclerosis [PDF]

Zagazig University Medical Journal
Background; Increasing evidence suggests that fibrinogen could play a pathogenic role in multiple sclerosis (MS). This study aimed to detect the relation between the plasma fibrinogen level and MS activities either clinically or radiologically.
Engy Emad, AbdAllah Sarhan, Zahraa Abd El-Wahed Abd Rabou, mohamed ismail   +3 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Relationship between plasma sialic acid and fibinogen concentration and incident micro-and macrovascular complications in type 1 diabetes [PDF]

, 2008
AIMS/HYPOTHESIS: Type 1 diabetes is associated with an increased risk of vascular complications. This increased risk could be explained by sialic acid and/or fibrinogen.
MICCOLI, ROBERTO, Pickup, J C, SOEDAMAH MUTHU SS, S. S. Soedamah-Muthu, J. H. Fuller, Chaturvedi, N, On behalf of EURODIAB PCS STUDY GROUP, CHATURVEDI N, Pickup, J.C., Fuller, J.H., Fuller, J H, FULLER JH, N. Chaturvedi, null null, PICKUP JC, J. C. Pickup, Soedamah-Muthu, S.S., Soedamah-Muthu, S S, Chaturvedi, N.   +18 more
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Fibrinogen and tumors

Frontiers in Oncology
Elevated plasma fibrinogen (Fg) levels consistently correlate with an unfavorable prognosis in various tumor patient cohorts. Within the tumor microenvironment, aberrant deposition and expression of Fg have been consistently observed, interacting with multiple cellular receptors and thereby accentuating its role as a regulator of inflammatory processes.
Xinyuan Wu, Xinyuan Wu, Xiaomin Yu, Cheng Chen, Chenlu Chen, Yuxin Wang, Dongyan Su, Liqing Zhu   +7 more
openaire   +3 more sources

Fibrinogen Assay

Clinical Chemistry, 1967
Abstract Precise, reproducible quantitation of fibrinogen from plasma using thrombin to convert it to fibrin requires careful attention to the technics of clot formation and syneresis. The precision of the method outlined indicates a coefficient of variation of 1.2% with replicate samples.
W R, Swaim, M B, Feders
openaire   +2 more sources

Modelling the association between fibrinogen concentration on admission and mortality in patients with massive transfusion after severe trauma: an analysis of a large regional database

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2018
Background The relationship between fibrinogen concentration and traumatic death has been poorly explored after severe trauma. Existing studies analysed this relationship in unselected trauma population, often considering fibrinogen concentration as a ...
Pierre Bouzat, François-Xavier Ageron, Jonathan Charbit, Xavier Bobbia, Pauline Deras, Jennifer Bas Dit Nugues, Etienne Escudier, Guillaume Marcotte, Marc Leone, Jean-Stéphane David   +9 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source