Results 21 to 30 of about 168,560 (263)
The Effect of Reagents Mimicking Oxidative Stress on Fibrinogen Function
Fibrinogen is one of the plasma proteins most susceptible to oxidative modification. It has been suggested that modification of fibrinogen may cause thrombotic/bleeding complications associated with many pathophysiological states of organism.
Jana Štikarová +6 more
doaj +1 more source
Variations on fibrinogen-erythrocyte interactions during cell aging. [PDF]
Erythrocyte hyperaggregation, a cardiovascular risk factor, is considered to be caused by an increase in plasma adhesion proteins, particularly fibrinogen.
Filomena A Carvalho +4 more
doaj +1 more source
This study evaluated whether rotational thromboelastometry (ROTEM; Tem International GmbH, Munich, Germany) FIBTEM maximum clot firmness (MCF) can be used to predict plasma fibrinogen level in pediatric patients undergoing cardiac surgery.
Christopher F. Tirotta MD, MBA +10 more
doaj +1 more source
Effect of L-NAME on the Synthesis of Plasma Fibrinogen in Mice
The effect of nitric oxide (NO) on plasma fibrinogen was investigated by treating mice with oral NG-nitro-L-arginine-methyl ester (L-NAME), a non-selective NO synthase (NOS) inhibitor.
Yasutaka Takinishi +2 more
doaj +1 more source
Fibrinogen is the major plasma protein coagulation factor. Low plasma fibrinogen concentrations are therefore associated with an increased risk of bleeding due to impaired primary and secondary haemostasis. Fibrinogen is a classical positive acute-phase reactant protein and is an independent predictor of coronary heart disease events.
Gordon D O, Lowe +2 more
openaire +2 more sources
Abstract Precise, reproducible quantitation of fibrinogen from plasma using thrombin to convert it to fibrin requires careful attention to the technics of clot formation and syneresis. The precision of the method outlined indicates a coefficient of variation of 1.2% with replicate samples.
W R, Swaim, M B, Feders
openaire +2 more sources
Fibrinogen replacement therapy for congenital fibrinogen deficiency [PDF]
This review of published studies was conducted to derive data on patients with congenital fibrinogen deficiency (CFD), including dosing of fibrinogen replacement therapy, outcome, and adverse events, either temporally related or distant to fibrinogen replacement, in order to assist clinicians in developing treatment plans for patients with CFD.
L, Bornikova +4 more
openaire +2 more sources
Young girl with congenital hypo-dysfibrogenemia presenting with an acute subdural haemorrhage
Fibrinogen plays a pivotal role in the coagulation cascade. Inherited fibrinogen disorders are a heterogenous group that includes lack or reduced fibrinogen levels or a qualitative disorder of fibrinogen, dysfibrinogenemia.
I. N. Walmsley +3 more
doaj +1 more source
In-depth characterization of N-glycosylation and sialic acid content in fetal and adult fibrinogen
Background: Fetal fibrinogen is a variant present in neonates. Blood products used in neonates are tailored for adults and do not seamlessly integrate into neonatal clots.
Tana V. Palomino +3 more
doaj +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source

