Results 21 to 30 of about 168,560 (263)

The Effect of Reagents Mimicking Oxidative Stress on Fibrinogen Function

open access: yesThe Scientific World Journal, 2013
Fibrinogen is one of the plasma proteins most susceptible to oxidative modification. It has been suggested that modification of fibrinogen may cause thrombotic/bleeding complications associated with many pathophysiological states of organism.
Jana Štikarová   +6 more
doaj   +1 more source

Variations on fibrinogen-erythrocyte interactions during cell aging. [PDF]

open access: yesPLoS ONE, 2011
Erythrocyte hyperaggregation, a cardiovascular risk factor, is considered to be caused by an increase in plasma adhesion proteins, particularly fibrinogen.
Filomena A Carvalho   +4 more
doaj   +1 more source

Correlation Between ROTEM FIBTEM Maximum Clot Firmness and Fibrinogen Levels in Pediatric Cardiac Surgery Patients

open access: yesClinical and Applied Thrombosis/Hemostasis, 2019
This study evaluated whether rotational thromboelastometry (ROTEM; Tem International GmbH, Munich, Germany) FIBTEM maximum clot firmness (MCF) can be used to predict plasma fibrinogen level in pediatric patients undergoing cardiac surgery.
Christopher F. Tirotta MD, MBA   +10 more
doaj   +1 more source

Effect of L-NAME on the Synthesis of Plasma Fibrinogen in Mice

open access: yesJournal of Pharmacological Sciences, 2005
The effect of nitric oxide (NO) on plasma fibrinogen was investigated by treating mice with oral NG-nitro-L-arginine-methyl ester (L-NAME), a non-selective NO synthase (NOS) inhibitor.
Yasutaka Takinishi   +2 more
doaj   +1 more source

Plasma fibrinogen [PDF]

open access: yesAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2004
Fibrinogen is the major plasma protein coagulation factor. Low plasma fibrinogen concentrations are therefore associated with an increased risk of bleeding due to impaired primary and secondary haemostasis. Fibrinogen is a classical positive acute-phase reactant protein and is an independent predictor of coronary heart disease events.
Gordon D O, Lowe   +2 more
openaire   +2 more sources

Fibrinogen Assay

open access: yesClinical Chemistry, 1967
Abstract Precise, reproducible quantitation of fibrinogen from plasma using thrombin to convert it to fibrin requires careful attention to the technics of clot formation and syneresis. The precision of the method outlined indicates a coefficient of variation of 1.2% with replicate samples.
W R, Swaim, M B, Feders
openaire   +2 more sources

Fibrinogen replacement therapy for congenital fibrinogen deficiency [PDF]

open access: yesJournal of Thrombosis and Haemostasis, 2011
This review of published studies was conducted to derive data on patients with congenital fibrinogen deficiency (CFD), including dosing of fibrinogen replacement therapy, outcome, and adverse events, either temporally related or distant to fibrinogen replacement, in order to assist clinicians in developing treatment plans for patients with CFD.
L, Bornikova   +4 more
openaire   +2 more sources

Young girl with congenital hypo-dysfibrogenemia presenting with an acute subdural haemorrhage

open access: yesAsian Journal of Internal Medicine, 2023
Fibrinogen plays a pivotal role in the coagulation cascade. Inherited fibrinogen disorders are a heterogenous group that includes lack or reduced fibrinogen levels or a qualitative disorder of fibrinogen, dysfibrinogenemia.
I. N. Walmsley   +3 more
doaj   +1 more source

In-depth characterization of N-glycosylation and sialic acid content in fetal and adult fibrinogen

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: Fetal fibrinogen is a variant present in neonates. Blood products used in neonates are tailored for adults and do not seamlessly integrate into neonatal clots.
Tana V. Palomino   +3 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

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