Results 41 to 50 of about 284,262 (205)

In-depth characterization of N-glycosylation and sialic acid content in fetal and adult fibrinogen

Research and Practice in Thrombosis and Haemostasis
Background: Fetal fibrinogen is a variant present in neonates. Blood products used in neonates are tailored for adults and do not seamlessly integrate into neonatal clots.
Tana V. Palomino, Anastasia Sheridan, David C. Muddiman, Ashley C. Brown   +3 more
doaj   +1 more source

The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease. [PDF]

, 2007
Perivascular microglia activation is a hallmark of inflammatory demyelination in multiple sclerosis (MS), but the mechanisms underlying microglia activation and specific strategies to attenuate their activation remain elusive.
Adams, Ryan A, Akassoglou, Katerina, Bauer, Jan, Degen, Jay L, Flick, Matthew J, Lassmann, Hans, Nuriel, Tal, Sikorski, Shoana L   +7 more
core  

Fibrin D-dimer, markers of coagulation activation and the risk of major ischaemic heart disease in the Caerphilly Study [PDF]

, 2001
We have previously reported that plasma fibrin D-dimer (a marker of turnover of cross-linked Fibrin) showed a strong and independent association with incident ischaemic heart disease (IHD) in the Caerphilly Study cohort of 1,998 men a-ed 49-65.
Lowe, G.D.O., Rumley, A., Rumley, J., Sweetnam, P.M., Yarnell, J.W.G.   +4 more
core   +1 more source

Identification of a novel zinc metalloprotease through a global analysis of clostridium difficile extracellular proteins [PDF]

, 2013
Clostridium difficile is a major cause of infectious diarrhea worldwide. Although the cell surface proteins are recognized to be important in clostridial pathogenesis, biological functions of only a few are known.
A Barketi-Klai, A Bateman, A Boetzkes, A Dhalluin, A Molla, A Tasteyre, A Tasteyre, A Tasteyre, A Wright, A Wright, AJ Waligora, B Singh, BR Hoffmann, C Janoir, C Schwan, CB Reynolds, CC Häse, CM Surawicz, D Lyras, D Zhang, Davide Serruto, DC Nelson, DE Voth, DJ Rigden, E Calabi, E Calabi, EJ Kuipers, F Tonello, FH Niesen, Francesca Cantini, G Bensi, GA Dalkas, GM Slynn, H Maeda, I Poilane, Jeffrey T. Rubino, JM Kirby, JR O'Connor, JW Teo, K Mukherjee, K Yokoyama, KR Klimpel, L de la Riva, L Tulli, LG Pacheco, M Cerquetti, M Desvaux, M Miura, M Monot, M Rupnik, M Sebaihia, M Warny, MA Breidenbach, Manuele Martinelli, Maria Scarselli, Massimiliano Biagini, Meera Unnikrishnan, Mikael Skurnik, MJ Rodríguez-Ortega, N Sengupta, Nathalie Norais, NM Hooper, NS Duesbery, O Schneewind, Rosanna Leuzzi, RP Fagan, S Péchiné, S Péchiné, S Ravipaty, SA Kuehne, T Karasawa, T Karjalainen, TC Dingle, Valeria Cafardi   +73 more
core   +8 more sources

Fibrinogen and tumors

Frontiers in Oncology
Elevated plasma fibrinogen (Fg) levels consistently correlate with an unfavorable prognosis in various tumor patient cohorts. Within the tumor microenvironment, aberrant deposition and expression of Fg have been consistently observed, interacting with multiple cellular receptors and thereby accentuating its role as a regulator of inflammatory processes.
Xinyuan Wu, Xinyuan Wu, Xiaomin Yu, Cheng Chen, Chenlu Chen, Yuxin Wang, Dongyan Su, Liqing Zhu   +7 more
openaire   +3 more sources

Modelling the association between fibrinogen concentration on admission and mortality in patients with massive transfusion after severe trauma: an analysis of a large regional database

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2018
Background The relationship between fibrinogen concentration and traumatic death has been poorly explored after severe trauma. Existing studies analysed this relationship in unselected trauma population, often considering fibrinogen concentration as a ...
Pierre Bouzat, François-Xavier Ageron, Jonathan Charbit, Xavier Bobbia, Pauline Deras, Jennifer Bas Dit Nugues, Etienne Escudier, Guillaume Marcotte, Marc Leone, Jean-Stéphane David   +9 more
doaj   +1 more source

Determinants of fibrinogen in an Italian population suffering from claudication. Lower fibrinogen in the south compared to middle and north of Italy. The ADEP Group. [PDF]

, 1998
Prospective studies have shown that high plasma levels of fibrinogen are independently associated with the risk of cardiovascular complications. In patients suffering from peripheral vascular disease (PVD) fibrinogen has been shown to be an independent ...
A. Longoni, BASILI, Stefania, IULIANO, Luigi, M. Milani, M. Vieri, VIOLI, Francesco   +5 more
core  

Adsorption of proteins to thin-films of PDMS and its effect on the adhesion of human endothelial cells [PDF]

, 2011
This paper describes a simple and inexpensive procedure to produce thin-films of poly(dimethylsiloxane). Such films were characterized by a variety of techniques (ellipsometry, nuclear magnetic resonance, atomic force microscopy, and goniometry) and ...
Bizios, Rena, Castro Guerrero, Carlos, Chumbimuni Torres, Karin Y., Coronado, Ramon E., Garcia, Carlos D., Mfuh, Adelphe M., Negrete, George R., Silva, María Fernanda   +7 more
core   +2 more sources

Air temperature and inflammatory and coagulation responses in men with coronary or pulmonary disease during the winter season [PDF]

, 2010
Background and Objective Air temperature changes are associated with increased cardiovascular and respiratory risk, but the roles of inflammatory and coagulation markers are not well understood.
Breitner, Susanne, Frampton, Mark W., Hampel, Regina, Koenig, Wolfgang, Peters, Annette, Phipps, Richard P., Rückerl, Regina, Schneider, Alexandra, Wichmann, Heinz-Erich   +8 more
core   +1 more source

Relationship between fibrinogen levels and cardiovascular events in patients receiving percutaneous coronary intervention: a large single-center study

Chinese Medical Journal, 2019
. Background:. It is currently unclear if fibrinogen is a risk factor for adverse events in patients receiving percutaneous coronary intervention (PCI) or merely serves as a marker of pre-existing comorbidities and other causal factors.
Ping Jiang, Zhan Gao, Wei Zhao, Ying Song, Xiao-Fang Tang, Jing-Jing Xu, Huan-Huan Wang, Lin Jiang, Jue Chen, Shu-Bin Qiao, Yue-Jin Yang, Run-Lin Gao, Bo Xu, Jin-Qing Yuan, Li-Min Chen   +14 more
doaj   +1 more source