Coarse Grain Molecular Dynamics Simulation of Fibrin Polymerization [PDF]
Studies suggests that patients with deep vein thrombosis and diabetes often have hy-per coagulable blood plasma leading to higher chances of forming thromboembolisms by the rupture of blood clots, which may lead to stroke and death. Despite the advances in the field of blood clot formation and lysis research, the change in mechanical properties and its
arxiv +1 more source
Association of Factor V Secretion with Protein Kinase B Signaling in Platelets from Horses with Atypical Equine Thrombasthenia. [PDF]
BackgroundTwo congenital bleeding diatheses have been identified in Thoroughbred horses: Glanzmann thrombasthenia (GT) and a second, novel diathesis associated with abnormal platelet function in response to collagen and thrombin stimulation.Hypothesis ...
Blevins, G+4 more
core +1 more source
. Background:. It is currently unclear if fibrinogen is a risk factor for adverse events in patients receiving percutaneous coronary intervention (PCI) or merely serves as a marker of pre-existing comorbidities and other causal factors.
Ping Jiang+14 more
doaj +1 more source
Young girl with congenital hypo-dysfibrogenemia presenting with an acute subdural haemorrhage
Fibrinogen plays a pivotal role in the coagulation cascade. Inherited fibrinogen disorders are a heterogenous group that includes lack or reduced fibrinogen levels or a qualitative disorder of fibrinogen, dysfibrinogenemia.
I. N. Walmsley+3 more
doaj +1 more source
MD simulations and experiments of plasma proteins adsorption to the biodegradable magnesium alloys to facilitate cell response [PDF]
Once the magnesium alloy was implanted in the body, it was immediately covered with plasma proteins. The coated alloy surface promoted the adsorption and growth of osteoblasts. Herein, in vitro biological reactions of the ZK60 and AZ31 magnesium alloys were analyzed with and without plasma proteins incubation.
arxiv
Effective modelling of adsorption monolayers built of complex molecules [PDF]
Random sequential adsorption algorithm is a popular tool for modelling structure of monolayers built in irreversible adsorption experiments. However, this algorithm becomes very inefficient when the density of molecules in a layer rises. This problem has already been solved for a very limited range of basic shapes.
arxiv +1 more source
Elevated Baseline Serum Fibrinogen: Effect on 2-Year Major Adverse Cardiovascular Events Following Percutaneous Coronary Intervention. [PDF]
BackgroundElevated fibrinogen is associated with short-term major adverse cardiovascular events (MACE) after percutaneous coronary intervention, but the relation with late MACE is unknown.Methods and resultsBaseline demographics and 2-year MACE were ...
Ang, Lawrence+7 more
core +1 more source
Elevated plasma fibrinogen (Fg) levels consistently correlate with an unfavorable prognosis in various tumor patient cohorts. Within the tumor microenvironment, aberrant deposition and expression of Fg have been consistently observed, interacting with multiple cellular receptors and thereby accentuating its role as a regulator of inflammatory processes.
Xinyuan Wu+7 more
openaire +3 more sources
To date, data regarding the efficacy and safety of administering fibrinogen concentrate in cardiac surgery are limited. Studies are limited by their low sample size and large heterogeneity with regard to the patient population, by the timing of ...
Gabor Erdoes+11 more
semanticscholar +1 more source
Associations of inflammatory and hemostatic variables with the risk of recurrent stroke [PDF]
<p><b>Background and Purpose:</b> Several prospective studies have shown significant associations between plasma fibrinogen, viscosity, C-reactive protein (CRP), fibrin D-dimer, or tissue plasminogen activator (tPA) antigen and the risk
Campbell, D.J.+10 more
core +1 more source