PURPOSE: The aim of this study was to examine the relation of late-stage age-related macular degeneration (AMD) with markers of systemic atherothrombosis. METHODS: A hospital-based case-control study of AMD was undertaken in London, UK.
A R Rudnicka +59 more
core +1 more source
Adsorption of proteins to thin-films of PDMS and its effect on the adhesion of human endothelial cells [PDF]
This paper describes a simple and inexpensive procedure to produce thin-films of poly(dimethylsiloxane). Such films were characterized by a variety of techniques (ellipsometry, nuclear magnetic resonance, atomic force microscopy, and goniometry) and ...
Bizios, Rena +7 more
core +2 more sources
Fibrin D-dimer, markers of coagulation activation and the risk of major ischaemic heart disease in the Caerphilly Study [PDF]
We have previously reported that plasma fibrin D-dimer (a marker of turnover of cross-linked Fibrin) showed a strong and independent association with incident ischaemic heart disease (IHD) in the Caerphilly Study cohort of 1,998 men a-ed 49-65.
Lowe, G.D.O. +4 more
core +1 more source
Fibrinogen Early In Severe Trauma studY (FEISTY): study protocol for a randomised controlled trial
Background Haemorrhage is a leading cause of death in severe trauma. Fibrinogen plays a critical role in maintaining haemostasis in traumatic haemorrhage. Early fibrinogen replacement is recommended by several international trauma guidelines using either
James Winearls +15 more
doaj +1 more source
D-Dimer Combined with Fibrinogen Predicts the Risk of Venous Thrombosis in Fracture Patients
Objective. While D-dimer can successfully diagnose venous thrombosis due to its excellent negative predictive value (NPV), it cannot be used to detect venous thromboembolism (VTE) because of its low positive predictive value (PPV).
Chaohui Lin +5 more
doaj +1 more source
Effects of moderate weight loss on anginal symptoms and indices of coagulation and fibrinolysis in overweight patients with angina pectoris [PDF]
Objective: To evaluate the effects of moderate weight loss, in overweight patients with angina, on plasma coagulation, fibrinolytic indicies and pain frequency.
Hankey, C.R. +4 more
core +1 more source
Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD
Impaired secretion of an essential blood coagulation factor fibrinogen leads to hepatic fibrinogen storage disease (HFSD), characterized by the presence of fibrinogen-positive inclusion bodies and hypofibrinogenemia.
Zhenfeng Song +17 more
doaj +1 more source
Background Fibrinogen is a central player in the blood coagulation cascade and one of the most abundant plasma proteins. This glycoprotein also triggers important events (e.g., cell spreading, the respiratory burst and degranulation) in neutrophil cells ...
Tiziana Alberio +5 more
doaj +1 more source
A new gas discharge process for preparation of non-fouling surfaces on biomaterials [PDF]
A non-fouling surface containing immobilized polyethylene oxide (PEO) was achieved using an argon radio-frequency glow discharge treatment (RFGD) of polyethylene films precoated with Brij hydrocarbon-PEO surfactants.
Feijen, J. +3 more
core +2 more sources
A 26-year-old pregnant woman with mild gingival bleeding
Congenital dysfibrinogenemia is a genetic coagulopathy that leads to compromised fibrinogen function. This case report describes a 26-year-old pregnant woman at the 38th week of gestation who presented with mild gingival bleeding and constant bruising on
J.Z. Zeng +7 more
doaj +1 more source

