Results 21 to 30 of about 361 (145)

Mast Cells and Fibrinolysin [PDF]

open access: yesNature, 1961
DURING the investigation of human tissues for fibrinolytic activity the presence of a fibrinolytic substance was detected in a specimen of a spleen. This was a case of splenic mastocytosis previously reported1 in which there were many mast cells and a high concentration of histamine and heparin in the splenic tissue.
N, ENDE, J V, AUDITORE
openaire   +2 more sources

THE CONCENTRATION OF FIBRINOLYSIN SOLUTIONS CONTAINING GLYCEROL

open access: yes, 1963
A simple technique is described for using dry Sephadex G25 to concentrate solutions of fibrinolysin dissolved in a solution containing 50% of glycerol as a stabilizer.
George A. McVicar, Robert H. Painter
core   +2 more sources

Various aspects of thrombolysis and fibrinolysis [PDF]

open access: yes, 1969
The author has described modern thrombolytic therapy of arterial and venous thrombosis and emboli by therapeutic fibrinolysis and other drugs also methods and effects of local and parenteral application of fibrinolysin preparations, dosage, control ...
Szirmai, E.
core   +1 more source

HUMAN FIBRINOLYSIN WITH AND WITHOUT UROKINASE: ITS EFFECT ON EXPERIMENTAL ARTERIAL THROMBI IN DOGS

open access: yes, 1962
The lytic effects of heat-treated, sterile solutions of spontaneously activated and urokinase-activated fibrinolysin on occlusive experimental arterial clots have been studied.
Walter H. E. Roschlau, Robert H. Painter
core   +2 more sources

Mechanisms of Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury

open access: yesmBio, 2013
Systems biology offers considerable promise in uncovering novel pathways by which viruses and other microbial pathogens interact with host signaling and expression networks to mediate disease severity.
Lisa E. Gralinski   +20 more
doaj   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

open access: yesAngewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma   +5 more
wiley   +2 more sources

A microchip developed for detecting antibodies against plaque-derived antigens

open access: yesИнфекция и иммунитет, 2019
Currently available Russia-made preparations intended for serological plague diagnostics are usually aimed at detecting antibodies to single bacterial antigens in the blood serum.
D. V. Utkin   +5 more
doaj   +1 more source

Characteristics of fibrinolysin secreted by cultured rat breast carcinoma cells

open access: yes, 1975
Fibrinolysin secreted by cultured R2426 rat breast carcinoma cells has been purified and partially characterized. Three methods of assay were used: the hydrolysis of [ 125I]fibrinogen and N-p-tosyl- l-arginine methyl ester (TAME), and clearing of fibrin ...
Arimura, G.K   +4 more
core   +1 more source

Cancer Cells in the Blood: Possibility of a Combined Treatment with Nitrogen Mustards, Fibrinolysin and Heparin

open access: yes, 1964
1) No cancer cells were detected at any time in the vena cava and aortic blood after the inoculation of nitrogen mustard. However when the mustard was administered in animals treated with fibrinolysin or with heparin cancer cells riappeared in the ...
Domenico Agostino, Eugene E. Cliffton
core   +1 more source

A novel biosensor for measuring plasmin activity

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: Plasmin facilitates fibrinolysis by catalyzing the degradation of fibrin clots. Reliable methods to assess fibrinolysis by measuring plasmin generation are needed in the preclinical and clinical settings.
Ying Dai   +4 more
doaj   +1 more source

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