Results 21 to 30 of about 2,769 (201)

Various aspects of thrombolysis and fibrinolysis [PDF]

open access: yes, 1969
The author has described modern thrombolytic therapy of arterial and venous thrombosis and emboli by therapeutic fibrinolysis and other drugs also methods and effects of local and parenteral application of fibrinolysin preparations, dosage, control ...
Szirmai, E.
core   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

open access: yesAngewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma   +5 more
wiley   +2 more sources

Mechanisms of Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury

open access: yesmBio, 2013
Systems biology offers considerable promise in uncovering novel pathways by which viruses and other microbial pathogens interact with host signaling and expression networks to mediate disease severity.
Lisa E. Gralinski   +20 more
doaj   +1 more source

Chemical Synthesis and Functional Screening of an 800 000‐Member Library Using a Peptide‐Pairing Strategy

open access: yesAngewandte Chemie, EarlyView.
Chemical peptide synthesis allows the generation of structurally highly diverse compounds suited for ligand development, but current methods in parallel peptide synthesis limit the achievable library size to a few thousand. A strategy is presented based on combinatorial pairing of short peptides via disulfide linkage that enables the generation and ...
Anne Zarda   +5 more
wiley   +2 more sources

A microchip developed for detecting antibodies against plaque-derived antigens

open access: yesИнфекция и иммунитет, 2019
Currently available Russia-made preparations intended for serological plague diagnostics are usually aimed at detecting antibodies to single bacterial antigens in the blood serum.
D. V. Utkin   +5 more
doaj   +1 more source

The effect of fibrinolysin ointment in the treatment of burn scars: A narrative review article

open access: yesIranian Journal of Burns and Wound Research
Burn injuries are a significant global health concern, ranking among the most common causes of trauma and leading to severe physical, functional, and psychosocial consequences.
Jafar Kazemzadeh
doaj   +1 more source

Characteristics of fibrinolysin secreted by cultured rat breast carcinoma cells

open access: yes, 1975
Fibrinolysin secreted by cultured R2426 rat breast carcinoma cells has been purified and partially characterized. Three methods of assay were used: the hydrolysis of [ 125I]fibrinogen and N-p-tosyl- l-arginine methyl ester (TAME), and clearing of fibrin ...
Arimura, G.K   +4 more
core   +1 more source

HUMAN FIBRINOLYSIN WITH AND WITHOUT UROKINASE: ITS EFFECT ON EXPERIMENTAL ARTERIAL THROMBI IN DOGS

open access: yes, 1962
The lytic effects of heat-treated, sterile solutions of spontaneously activated and urokinase-activated fibrinolysin on occlusive experimental arterial clots have been studied.
Walter H. E. Roschlau, Robert H. Painter
core   +1 more source

THE CONCENTRATION OF FIBRINOLYSIN SOLUTIONS CONTAINING GLYCEROL

open access: yes, 1963
A simple technique is described for using dry Sephadex G25 to concentrate solutions of fibrinolysin dissolved in a solution containing 50% of glycerol as a stabilizer.
George A. McVicar, Robert H. Painter
core   +1 more source

MICROBIOLOGICAL ASPECTS OF STAPHYLO- COCCAL INFECTIONS TODAY [PDF]

open access: yesAnnals of Mechnikov's Institute, 2013
Overview summarizes the data of the domestic and for-eign literature about the prevalence and biological prop-erties of S. aureus. S. аureus enzymes of aggression andpathogenicity factors (capsular polysaccharides, differentextracellular protein ...
Ponomarenko S.V.
doaj  

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