Results 41 to 50 of about 2,769 (201)

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu, Gui‐Qin Liu, Ya‐Ping Peng, Li‐Ling Zhang, Xian‐Jin Wang, Liang‐Chuan Chen, Yuan‐Xi Zheng, Xue‐Jun Xiang, Rui Qiao, Xian‐He Lin   +9 more
wiley   +1 more source

Pharmacological pain relief and postpartum bleeding in women with moderate or severe anemia: A cohort analysis of the WOMAN‐2 trial

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Pain relief could minimize blood loss by limiting the adrenaline stress response to fear and trauma during birth. We examined the association between pharmacological pain relief and postpartum bleeding in a large cohort of women giving birth with anemia in sub‐Saharan Africa and South Asia.
Judith Lieber, Monica Arribas, Maha Asad, Eni Balogun, Folasade Adenike Bello, Amy Brenner, Rizwana Chaudhri, Amber Geer, Kiran Javaid, Aasia Kayani, Katharine Ker, Mwansa Ketty Lubeya, Raoul Mansukhani, Projestine Muganyizi, Oladapo Olayemi, Danielle Prowse, Ian Roberts, Haleema Shakur‐Still, Bellington Vwalika, The WOMAN‐2 Trial Collaborators, France Donnay, Racheal Phiri, Tina Lavender, Ghazala Mahmud, Jens Kieckbusch, James Lawrence, Sari Watson, Jane Armitage, Maria Quigley, Olufemi T. Oladapo, Sabaratnam Arulkumaran, Imelda Bates, Bukola Fawole, Danielle Prowse, Danielle Beaumont, Charlotte Fleming, Collette Barrow, Llion Roberts, Julio Gil Onandia, Madeleine Cargill, Andrew Thayne, Christiana Alao, Petula Buck, Raoul Mansukhani, Tim Collier, Mbwana Mohammed, Myriam Benyahia, Projestine Muganyizi, Alice Kawala, Rose Temba, Oladapo Olayemi, Olujide Okunade, Bellington Vwalika, Aziz‐un‐Nisa Abbasi, Ruqqia Sultana, Shehla Noor, Ansa Islam, Sadia Bibi, Sundus Khan, Wajeeha Khurshid, Shahida Magsi, Basma Zia, Haleema Yasmin, Khadija Bano, Saba Khan, Naheed Fatima, Bushra Sher Zaman, Sohail Mahmood Chaudhry, Shakila Yasmin, Khiaynat Sarwar Hashmi, Nadia Babar, Arif Tajammul, Alia Bashir, Farah Siddique, Fouzia Perveen, Nusrat Shah Kamal, Riffat Jaleel, Sarah Kazi, Aruna Hira, Pushpa Makhija, Syeda Batool Mazhar, Nasira Tasnim, Saera Afghan, Mussarat Batool, Sobia Luqman, Fouzia Kashif, Shaista Hifaz Abro, Javeria Abro, Najma Ghaffar, Rakhshanda Mushtaq, Safia Bibi, Shamsa Humayun, Zohra Khanum, Noreen Akmal, Shamila Ijaz Munir, Aisha Malik, Amna Zia Eusaph, Sofia Manzoor, Khola Yousaf, Misbah Kausar, Yasmeen Waqas, Naila Ehsan, Aisha Siddiqa, Uzma Suhail Afridi, Nosheen Sikandar, Rehana Kamaal, Mehnaz Khakwani, Rashida Perveen, Huma Quddusi, Hajira Masood, Syeda Ali, Asma Akhter, Mubashra Samina, Sana Ishfaque, Humaira Bilqis, Shahid Irshad Rao, Saima Ashraf, Uzma Shaheen, Tayyiba Wasim, Natasha Rasool, Nabeela Waheed, Khansa Iqbal, Shahida Husain Tarar, Rizwana Khalid, Rubina Sohail, Shehla Kanwal, Shagufta Saeed Sial, Humera Noreen, Naila Israr, Shehla Baqai, Asifa Siraj, Luzango Maembe, Julius Nyambarino, Enid Simon Chiwanga, Lazaro Y. Madeha, Francis Ngimwichi Joseph, Evelyne Ludovick, Baya H Kissiwa, Sangalala Mtingele, Vincent Tarimo, Alfred Secha, Hudson August Manyanga, Idrisa Hussein, Alphonce Moyo, Delila Msigwa, France John Rwegoshora, Delfina Mkenda, Mojisola Mobolaji‐Ojibara, Michael Babalola, Owa Olorunfemi Oludele, Samuel Ojo, Oladipo Aremu, Kehinde Ogundairo, Oyewole Tunde Aremu, Gazaal Rasheedat, Iman Usman, Auwal Shuaibu, Adewale Adeyemi, Olufemi Aworinde, Theresa Irinyenikan, Mwansa Ketty Lubeya, Kenneth Chanda   +161 more
wiley   +1 more source

Antifibrinolytic Activity of Derivatives of Fibrinolysin.

Experimental Biology and Medicine, 1956
SummaryDerivatives of bovine fibrinolysin have been prepared which inhibited the enzyme from which they are derived, but did not inhibit human fibrinolytic activity.
I, DJERASSI, E, KLEIN
openaire   +2 more sources

Establishment of Reference Intervals for Thrombus Biomarkers in a Single‐Center Chinese Population Using Indirect Methods

Journal of Clinical Laboratory Analysis, EarlyView.
This study established and validated comprehensive RIs for four key thrombus biomarkers (TAT, PIC, TM, and t‐PAIC) in a Chinese population using the Hoffmann and Bhattacharya indirect methods on a large clinical dataset. The tailored RIs offer a practical tool for early detection and risk assessment of thrombotic diseases, supporting more precise and ...
Lei Zhang, Qiyu Hu, Yiming Chen, Hui Yuan   +3 more
wiley   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Role of defensins in immunothrombosis

Rheumatology &Autoimmunity, EarlyView.
Defensins are important proteins that link the immune system and blood clotting, playing a key role in immunothrombosis. α‐defensins mainly come from neutrophils, while β‐defensins are produced by epithelial cells and platelets. These proteins help form blood clots in several ways: they slow down clot breakdown (fibrinolysis), activate platelets, and ...
Yuebing Wang, Guijuan Guo, Xiangjun Liu, Xiaoyu Chen, Wenqiong Wang, Patapong Towiwat, Ru Li, Chun Li   +7 more
wiley   +1 more source

A Rapid Method for the Estimation of Fibrinolytic Changes in the Dog

, 1958
The fibrinolytic system in the dog was studied for investigating possible etiological factors concerned with the bleeding diathesis observed following surgery and shock.
R. A. Heinrich, E. C. Vonder Heide, F. E. Noe   +2 more
core   +1 more source

Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang, Chen Zhang, Jia‐Ni Chen, Fu‐Ying Cheng, Yi‐Zhang Wang, Shi‐Rui Xue, Huan Wang, De‐Hui Wang, Xi‐Cai Sun, Li Hu   +9 more
wiley   +1 more source

Changes of Microbial and Component Composition of Giraffe Milk During Mid‐ to Late Lactation

Zoo Biology, EarlyView.
Giraffe milk – graphical abstract text, Giraffe: late lactation milk, Involution at approximately 15 months of lactation, Content of saccharides and fat decrease, Protein content increases, Content of minerals increase, Microbiological quality high ABSTRACT The proximate, mineral and microbiological composition of milk from five giraffes from mid ...
G. Osthoff, C. J Hugo, S Van der Merwe, A Hugo, F Deacon   +4 more
wiley   +1 more source

Evolutionary Mechanisms of Coagulation Factors in Cetaceans During Aquatic Adaptation

Integrative Zoology, EarlyView.
Compared with Bos taurus, T. truncatus showed shorter prothrombin time and thrombin time but prolonged activated partial thromboplastin time, indicating pathway‐specific remodeling of coagulation. Evolutionary analyses identified 18 positively selected genes and accelerated F11 evolution, while functional assays revealed increased coagulation factor ...
Wenjun Lv, Wanfei Deng, Fei Deng, Shixia Xu, Wenhua Ren   +4 more
wiley   +1 more source