Results 61 to 70 of about 2,769 (201)
International Journal of Dermatology, EarlyView.Merlin CP‐GEP integrates mechanistic insights into a clinically actionable assay to predict SLN metastasis risk and inform personalized management of cutaneous melanoma. ABSTRACT The recent inclusion of the Merlin clinicopathologic–gene expression profile (CP‐GEP) assay in the National Comprehensive Cancer Network (NCCN) Melanoma Guidelines represents ...
Frank Z. Jing, Alexander Meves
wiley +1 more source
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic +3 more
wiley +1 more source
Coagulation and Fibrinolysis in Normal Pregnancy and Complicated Pregnancy
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Pregnancy induces significant physiological changes in the hemostatic system, leading to a hypercoagulable state to prevent postpartum hemorrhage. These adaptations involve alterations in coagulation and fibrinolysis, which can be further modified in complicated pregnancies such as gestational diabetes mellitus (GDM) and ...
Yang Su +6 more
wiley +1 more source
, 1947 1. Three. hundred and ninety -three strains of haemolytic streptococci from infective processes in animals were identified by means of Lancefield's precipitation test and their host association recorded.2. 94.7 per cent.
Garside, J. S.
core +3 more sources
Genetic Susceptibility to Periodontitis
Journal of Periodontal Research, EarlyView.Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley +1 more source
Periodontology 2000, EarlyView.AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer +4 more
wiley +1 more source
Effects of fibrinolytic agents and heparin on intravascular clot lysis
, 1964 Clots were prepared in glass or siliconized cannulae and inserted into jugular veins 5 cm distal to semiconstricting ligatures. Clots prepared in glass tubes propagated rapidly unless heparin was administered.
Jessica H. Lewis +2 more
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Transfusion Medicine, EarlyView.Abstract Objectives To highlight tranexamic acid (TXA) as ‘just one thing’ that every hospital could implement to reduce surgical bleeding and blood transfusions. Background TXA is a low‐cost antifibrinolytic agent that inhibits the breakdown of fibrin blood clots. Developed in Japan in the 1960s, it has been shown to reduce surgical bleeding.
Ian Roberts, Katharine Ker
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Stability of Thrombin in the Presence of Fibrinolysin.
Experimental Biology and Medicine, 1947 SummaryIt has been shown that fibrinolysin does not affect the clotting activity of thrombin, and that the thrombin preparation increased the stability of fibrinolysin under the conditions of these experiments.
openaire +3 more sources
Independence of activation of the fibrinolytic system from certain immunologic systems
, 1959 Activation of the immunologic system either in vitro or in vivo results in nearly complete consumption of complement without activation of the fibrinolytic system. However complement activity decreased upon the induction of fibrinolytic activity even in
S. N. Kolmen +2 more
core +1 more source