Targeted Therapy and Immunotherapies in Hepatocellular Carcinoma: Mechanisms and Clinical Studies
MedComm, Volume 7, Issue 5, May 2026.The mechanism of multiple signaling pathways and their related targeted inhibitors in HCC. (A) The mechanism of Ras/Raf/MEK/ERK signaling pathway and its related targeted inhibitors; (B) the mechanism of PI3K/AKT/mTOR signaling pathway and its crosstalk with other pathways and its related targeted inhibitors; (C) the mechanism of JAK/STAT signaling ...
Penghui He +9 more
wiley +1 more source
Indicators and Bacterial Diversity of Subclinical Mastitis in Iran's Industrial Cattle Farms
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.In this study, the relationship between milk lactose and somatic cell count and the prevalence of bacterial agents of subclinical mastitis was investigated. Klebsiella spp. was identified as the most common pathogen and showed a pattern of antibiotic resistance.
Roozbeh Kalantari +2 more
wiley +1 more source
Is the Urokinase Plasminogen Activator/Plasminogen Activator Inhibitor-1 Ratio a Marker of Sonographic Septations in Pleural Infection? [PDF]
Am J Respir Crit Care Med, 2023 Yasuma T +4 more
europepmc +1 more source
Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma
Allergy, Volume 81, Issue 5, Page 1571-1586, May 2026.Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...
Cong Dong +217 more
wiley +1 more source
Human α2‐Macroglobulin: Architecture, Mechanisms, and Functional Implications
The FASEB Journal, Volume 40, Issue 8, 30 April 2026.Visual representation of human α2‐macroglobulin in its native and induced conformations. General functions associated with the native form (green), the induced form (white), and both conformations (light red) are indicated. ABSTRACT α2‐Macroglobulin (α2M) is a large glycoprotein and one of the most abundant proteins found in the plasma of vertebrates ...
Pietro de Carvalho Andrade +2 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 7, 15 April 2026.Schematic illustrating the mechanism by which the peptide Angio‐3 attenuates pulmonary fibrosis. Following lung injury, activation of the coagulation cascade via Factor Xa (FXa) signals through protease‐activated receptor‐1 (PAR‐1) to activate fibroblasts and promote fibrosis.
Dan Wang +9 more
wiley +1 more source
Targeting the PAI-1 Mechanism with a Small Peptide Increases the Efficacy of Alteplase in a Rabbit Model of Chronic Empyema. [PDF]
Pharmaceutics, 2023 Florova G +10 more
europepmc +1 more source
Identification, and Clinical Relevance of Gram–Positive Spore Formers [PDF]
, 2010 The gram positive spore former constitutes a group of widely distributed infectious microorganism which has posed serious threat to public health. This group comprises the Bacillus, Clostridium, Staphylococcus and Streptococcus species.
Ajani, Olayinka O., Nwinyi, Obinna
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Influence of environmental factors on Streptococcus agalactiae isolated from active cases of bovine mastitis [PDF]
, 1953 Digitized 2007 AES.Includes bibliographical references (pages 33-39)
Gholson, James H. +1 more
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