Results 91 to 100 of about 2,769 (201)

Human Blood‐Brain Tumor Barrier on a Chip to Investigate Personalized Treatment for Glioblastoma Patients

Small, Volume 22, Issue 49, 1 September 2026.
A microfluidic model of the glioblastoma (GBM) margin was developed to mimic patient‐specific blood‐brain tumor barrier (BBTB) function and drug response. The platform revealed inter‐patient variability in barrier integrity and drug sensitivity, offering a tool for personalized therapy evaluation in GBM.
Minsu Ryoo, Gaeun Lee, Jinwoo Jung, Sujin Cho, Sharon Jeeho Ham, Nayeong Kang, Hyeongjin Ahn, Yu Jin Kim, JeongMin Sim, Jeongman Park, Juwon Kim, Sohyun Hwang, Jihwan Yoo, Youn‐Jung Kang, Jaejoon Lim, Jungho Ahn, Song Ih Ahn   +16 more
wiley   +1 more source

Various aspects of thrombolysis and fibrinolysis

The author has described modern thrombolytic therapy of arterial and venous thrombosis and emboli by therapeutic fibrinolysis and other drugs also methods and effects of local and parenteral application of fibrinolysin preparations, dosage, control ...
Szirmai, E.
core  

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

The FEBS Journal, Volume 293, Issue 18, Page 5558-5584, September 2026.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh, Ivan Gallotta, Bolanle F. Olabiyi, Yoon Hee Choi, Sarah Inglesfield, Janet R. Kumita, Collin Y. Ewald, Della C. David   +7 more
wiley   +1 more source

Fibrinolytic, anticoagulating and plasma-clotting properties of staphylococci

, 1937
In 1908, Much showed that plasma which had been coagulated by the plasma-clotting factor of staphylococci, may become re-dissolved. He attributed the lysis of the plasma clot to the action of a staphylococcus fibrinolysin.
Erwin Neter
core  

Advances in Skin Whitening Agents: Mechanisms, Clinical Applications, and Future Perspectives

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Skin hyperpigmentation disorders are common cosmetic and clinical concerns caused by excessive melanin production, abnormal pigment distribution, or persistent pigment after inflammation. Their heterogeneous pathogenesis and tendency to recur complicate treatment, particularly in patients with darker phototypes.
Yuanyuan Chen, Enhui Wang, Yize Li, Yanfang Yang, Zhaofeng Zhang, Junbo Wang, Yanfei Jiang, Chunyue Zhao   +7 more
wiley   +1 more source

Is the Urokinase Plasminogen Activator/Plasminogen Activator Inhibitor-1 Ratio a Marker of Sonographic Septations in Pleural Infection? [PDF]

Am J Respir Crit Care Med, 2023
Yasuma T, D'Alessandro-Gabazza CN, Kobayashi T, Gabazza EC, Fujimoto H.   +4 more
europepmc   +1 more source

Real-Time Fibrinolysis Monitoring of Plasma Annular Clots. [PDF]

Biomolecules
Trujillo AP, Umesh A, Hall A, Alves NJ.
europepmc   +1 more source

Targeting the PAI-1 Mechanism with a Small Peptide Increases the Efficacy of Alteplase in a Rabbit Model of Chronic Empyema. [PDF]

Pharmaceutics, 2023
Florova G, De Vera CJ, Emerine RL, Girard RA, Azghani AO, Sarva K, Jacob J, Morris DE, Chamiso M, Idell S, Komissarov AA.   +10 more
europepmc   +1 more source

Leptospira glyceraldehyde-3-phosphate dehydrogenase (LiGAPDH): a cell-surface plasminogen binding protein. [PDF]

FEMS Microbiol Lett
de Souza MCL, Nepomuceno R, Santos CM, Abe CM, Barbosa AS.   +4 more
europepmc   +1 more source

Plasmin-mediated fibrinolysis is required for hematopoietic recovery after 5-FU-induced myeloablation. [PDF]

Blood Adv
Nguyen TP, Jiang YG, Ogan BM, Doyle AD, Tran DT, Ward JM, Zhang A, Ferrer de Oliveira R, Ferraresso F, Bledsoe JR, Kastrup CJ, Flick MJ, Rowe RG, Bugge TH, Silva LM.   +14 more
europepmc   +1 more source