Results 141 to 150 of about 127,027 (324)

Effects of intracameral tissue plasminogen activator injection on posterior capsular opacification, fibrin formation, and intraocular pressure in dogs after phacoemulsification

open access: yesVeterinary Ophthalmology, EarlyView.
Abstract Objective To evaluate whether intracameral tissue plasminogen activator (tPA) injection is effective in regulating posterior capsular opacification (PCO), fibrin formation and intraocular pressure (IOP) after cataract surgery. Animal Studied Prospective study involving 30 eyes of 21 dogs that underwent phacoemulsification.
Kyulee Kim   +2 more
wiley   +1 more source

The significance of fibrinolysis occurring in patients with metastatic cancer of the prostate [PDF]

open access: bronze, 1953
Henry J. Tagnon   +3 more
openalex   +1 more source

Early ST elevation myocardial infarction in non-capable percutaneous coronary intervention centres: in situ fibrinolysis vs. percutaneous coronary intervention transfer.

open access: yesEuropean Heart Journal, 2016
AIMS The preferred reperfusion strategy for early ST elevation myocardial infarction (STEMI, defined as time from symptoms onset ≤120 min) in non-capable percutaneous coronary intervention (PCI) centres remains controversial.
X. Carrillo   +12 more
semanticscholar   +1 more source

Deferasirox Derivatives as Inhibitors of Kallikrein‐Related Peptidases Associated to Neurodegenerative Diseases

open access: yesChemMedChem, Volume 20, Issue 13, July 1, 2025.
Dysregulated proteolysis mediated by kallikrein‐related peptidases (KLKs) and iron overload are involved in the progression of neurodegenerative diseases. Deferasirox, an clinically‐approved iron chelator, and its newly synthesized derivatives have been identified as inhibitors of major central nervous system KLKs with low cytotoxicity and effective ...
Rilès Boumali   +11 more
wiley   +1 more source

Impaired Whole-Blood Fibrinolysis is a Predictor of Mortality in Intensive Care Patients

open access: yesTH Open
Background Altered fibrinolysis is considered to play a crucial role in the development of coagulopathy in sepsis. However, routine laboratory tests for fibrinolysis are currently very limited, and the impact of fibrinolytic capacity on ...
Julie S. Brewer   +3 more
doaj   +1 more source

Hypomethylation‐Triggered SERPINE1 (Serpin Family E Member 1) Exacerbates Polycystic Ovary Syndrome with Hyperandrogenism Induced by Circadian Disruption

open access: yesMedComm, Volume 6, Issue 7, July 2025.
SERPINE1 shows CpG hypomethylation near its TSS of promoter region when exposed to circadian disruption, and its gene expression triggers hyperandrogenism through the PI3K/AKT pathway. SERPINE1 inhibitor TPX can significantly decrease serum SERPINE1 levels and reduce abnormally high testosterone levels in both continuous darkness‐exposed rats and DHEA ...
Xueying Geng   +8 more
wiley   +1 more source

Different effects of oral and transdermal hormone replacement therapies on Factor IX, APC resistance, t-PA, PAI and C- reactive protein - a cross-sectional population survey [PDF]

open access: yes, 2001
The effects of hormone replacement therapy (HRT) on thrombosis risk, thrombotic variables, and the inflammatory marker C- reactive protein (CRP) may vary by route of administration (oral versus transdermal).
Lowe, G.D.O.   +5 more
core  

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

open access: yesSmall Structures, Volume 6, Issue 7, July 2025.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han   +11 more
wiley   +1 more source

The role of ACTH and glucocorticoids in nonenzymatic fibrinolysis during immobilization stress in animals [PDF]

open access: yes
The role of the altered hormonal status of an organism in the activation of the anticoagulative system during stress is investigated. The 30 minute immobilization stress was shown to raise significantly the nonenzymatic fibrinolytic activity of blood in ...
Kudryashov, B. A.   +3 more
core   +1 more source

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