Results 141 to 150 of about 80,628 (257)

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

open access: yesPeriodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer   +4 more
wiley   +1 more source

Freeze‐dried plasma: Hemostasis and biophysical analyses for damage control resuscitation

open access: yesTransfusion, EarlyView.
Abstract Background Effective hemorrhage protocols prioritize immediate hemostatic resuscitation to manage hemorrhagic shock. Prehospital resuscitation using blood products, such as whole blood or alternatively dried plasma in its absence, has the potential to improve outcomes in hemorrhagic shock patients.
Aron A. Shoara   +16 more
wiley   +1 more source

Tranexamic acid is associated with post‐injury mortality in a resource‐limited trauma system: Findings from the epidemiology and outcomes of prolonged trauma care cohort study

open access: yesTransfusion, EarlyView.
Abstract Background Injury‐related deaths claim millions of lives annually, with severe hemorrhage a leading cause. This study assesses tranexamic acid (TXA) administered within 3 h post‐injury on mortality in trauma patients. Study Design And Methods We conducted secondary database analysis of EpiC, a multicenter, prospective cohort of trauma patients
Adane F. Wogu   +21 more
wiley   +1 more source

Sex‐based disparities in low‐titer O whole blood utilization and mortality among severely injured trauma patients

open access: yesTransfusion, EarlyView.
Abstract Background Low‐titer O whole blood (LTOWB) is commonly used in the United States for severe bleeding. Our objective was to examine disparities in LTOWB utilization and its association with survival. Study Design and Methods This retrospective analysis included patients receiving at least 1 L of red blood cells (RBC) or LTOWB in the first 4 h ...
Skye Clayton   +5 more
wiley   +1 more source

Effects of intracameral tissue plasminogen activator injection on posterior capsular opacification, fibrin formation, and intraocular pressure in dogs after phacoemulsification

open access: yesVeterinary Ophthalmology, EarlyView.
Abstract Objective To evaluate whether intracameral tissue plasminogen activator (tPA) injection is effective in regulating posterior capsular opacification (PCO), fibrin formation and intraocular pressure (IOP) after cataract surgery. Animal Studied Prospective study involving 30 eyes of 21 dogs that underwent phacoemulsification.
Kyulee Kim   +2 more
wiley   +1 more source

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