Results 141 to 150 of about 47,940 (267)

Obesity‐Related Coagulation Activation in Adolescents and Children: A Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
Obesity is widely recognized as a pro‐thrombotic condition, yet the specific biomarker profile reflecting coagulation activation remains incompletely defined. Obesity is associated with increased coagulation activation, particularly in children, suggesting an early pro‐thrombotic shift.
Julia Buchold, Hans‐Jonas Meyer, Manuel Florian Struck, Shrey Kohli, Akash Mathew, Gyulten Mangova, Alexey Surov, Matthias Blüher, Berend Isermann, Silke Zimmermann   +9 more
wiley   +1 more source

Dyslipidemias and fibrinolysis.

, 2002
BACKGROUND: The relation between fibrinolysis and cardiovascular disease is an open debate. Fibrinolysis is related to endothelial function and presents many molecular links with platelet and coagulation activity.
BRUNI, FULVIO, PALAZZUOLI, ALBERTO, PUCCETTI, LUCA, PASTORELLI, MARCELLO, Bova G, Cercignani M, Auteri A., PASQUI, ANNA LAURA   +7 more
core  

Platelet Levels Associated With Bleeding Risk for Dental Interventions: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objectives To evaluate evidence in relation to postoperative bleeding in humans aged ≥ 16 with preoperative platelet counts < 50,000/μL, compared to those above, undergoing dental interventions. Methods Quantitative synthesis without meta‐analysis was conducted through an electronic search conducted on Ovid MEDLINE and Embase from 1946 to ...
Guang Xu David Lim, Fatima Al Sarraf, Hana Cho, Navdeep Kumar   +3 more
wiley   +1 more source

Neutrophil extracellular traps formation is associated with impaired clot retraction and fibrinolysis in asthma

Frontiers in Immunology
BackgroundAsthma is associated with an elevated risk of venous thromboembolism and pulmonary embolism; its etiology is not completely understood.ObjectiveThis study was designed to investigate whether the formation of neutrophil extracellular traps (NET)
Tomasz Misztal, Maria Magdalena Tomasiak-Łozowska, Aleksandra Poznalska, Wiktoria Ciochanowska, Tomasz Rusak, Marcin Moniuszko   +5 more
doaj   +1 more source

Metformin Use Is Associated With Reduced Inflammation and Pain After Total Knee Arthroplasty in Patients With Type 2 Diabetes

Orthopaedic Surgery, EarlyView.
Long‐term metformin use in T2DM patients undergoing TKA significantly reduced postoperative inflammation and pain. On postoperative day 3, CRP, IL‐6, ESR, D‐dimer levels and VAS scores were markedly lower in the metformin group, suggesting potential perioperative anti‐inflammatory and analgesic benefits.
Zhongyu Luo, Xiaoying Zhong, Chen Zhang, Mingwei Hu, Muyang Yu, Bin Feng, Xisheng Weng   +6 more
wiley   +1 more source

Impaired Whole-Blood Fibrinolysis is a Predictor of Mortality in Intensive Care Patients

TH Open
Background Altered fibrinolysis is considered to play a crucial role in the development of coagulopathy in sepsis. However, routine laboratory tests for fibrinolysis are currently very limited, and the impact of fibrinolytic capacity on ...
Julie S. Brewer, Christine L. Hvas, Anne-Mette Hvas, Julie B. Larsen   +3 more
doaj   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Outcomes according to timely or delayed primary percutaneous coronary intervention or fibrinolysis in a national registry of patients with ST-segment elevation myocardial infarction

Open Heart
Background Time to reperfusion is a predictor of long-term outcomes in ST-segment elevation myocardial infarction (STEMI). Timely primary percutaneous coronary intervention (PCI) is the preferred strategy recommended by guidelines.
Peter Kearney, Richard Armstrong, JJ Coughlan, Andrew Maree, Thomas J Kiernan, James Crowley, Mark Kennedy, Robert A Byrne, Godfrey Aleong, Andrew Street, Jack Laffan, Charles McCreery, Gavin Blake, Aaron Peace, Huixuan Gao   +14 more
doaj   +1 more source

Thrombin-activatable fibrinolysis inhibitor

, 2004
The coagulation system is a potent mechanism that prevents blood loss after vascular injury. It consists of a number of linked enzymatic reactions resulting in thrombin generation. Thrombin converts soluble fibrinogen into a fibrin clot.
Marx, Pauline F.
core   +1 more source

Acute pain transfusion reaction in a patient with thalassemia: In‐depth characterization of short‐ and long‐term phenotypes

Transfusion, EarlyView.
Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa, Sophia Delicou, Ioanna Barla, Konstantina Theocharaki, Aggeliki Kondi, Athanassios D. Velentzas, Nikolaos Simantiris, Elli‐Anna Stylianaki, George Mpekoulis, Efthymia Pavlou, Niki Vassilaki, Ioannis V. Kostopoulos, Aikaterini Xydaki, Efrosyni Nomikou, Ioanna‐Katerina Aggeli, Nikolaos Thomaidis, Evangelos Gikas, Martina Samiotaki, Jerome Zoidakis, Constantina Politis, Marianna H. Antonelou   +20 more
wiley   +1 more source