Results 171 to 180 of about 80,628 (257)

High‐throughput amino acid‐level characterization of the interactions of plasminogen activator inhibitor‐1 with variably divergent proteases

open access: yesProtein Science, Volume 34, Issue 4, April 2025.
Abstract While members of large paralogous protein families share structural features, their functional niches often diverge significantly. Serine protease inhibitors (SERPINs), whose members typically function as covalent inhibitors of serine proteases, are one such family.
Laura M. Haynes   +4 more
wiley   +1 more source

The time course of alpha 2-plasmin inhibitor and plasmin-alpha 2-plasmin inhibitor complex levels in patients with traumatic brain injury. [PDF]

open access: yesActa Neurochir (Wien)
Kanaya T   +9 more
europepmc   +1 more source

Association of Anaesthetists guidelines: the use of blood components and their alternatives

open access: yesAnaesthesia, Volume 80, Issue 4, Page 425-447, April 2025.
Summary Background The administration of blood components and their alternatives can be lifesaving. Anaemia, bleeding and transfusion are all associated with poor peri‐operative outcomes. Considerable changes in the approaches to optimal use of blood components and their alternatives, driven by the findings of large randomised controlled trials and ...
Akshay Shah   +12 more
wiley   +1 more source

The Possible Role of Metformin and Fibroblast Growth Factor‐21 in Multiple Sclerosis Neuropathology: Birds of a Feather Flock Together

open access: yesEuropean Journal of Neuroscience, Volume 61, Issue 7, April 2025.
Predisposing factors of multiple sclerosis and Role of Metformin and Fibroblast Growth Factor‐21: A key predisposing factor for multiple sclerosis (MS) is genetic susceptibility, which is associated with an increased risk of the disease. Environmental factors, such as low vitamin D levels, smoking, and viral infections, also contribute to the ...
Ahmad A. Abulaban   +7 more
wiley   +1 more source

PB2644: NOVEL GLOBAL FIBRINOLYSIS CAPACITY ASSAYS: THE NEXT STEP IN FIBRINOLYSIS SCREENING?

open access: yesHemaSphere, 2023
Anton Evenepoel   +2 more
doaj   +1 more source

RELATIONSHIP OF PLATELETS, BLOOD COAGULATION, AND FIBRINOLYSIS TO HYPERACUTE REJECTION OF RENAL XENOGRAFTS

open access: bronze, 1969
J.C. Rosenberg   +5 more
openalex   +1 more source

Protofibril packing density of individual fibers alters fibrinolysis. [PDF]

open access: yesRes Pract Thromb Haemost
Risman RA   +4 more
europepmc   +1 more source

Identification of an exosite at the neutrophil elastase/alpha‐1‐antitrypsin interface

open access: yesThe FEBS Journal, Volume 292, Issue 8, Page 1887-1903, April 2025.
Molecular dynamics simulations predicted an exosite in the encounter complex between alpha‐1 antitrypsin (AAT) and neutrophil elastase (NE), comprising a patch of acidic residues which interacts with a basic loop on NE. Recombinant AAT variants with mutations of the three acidic residues show reduced association rate compared to wild‐type and confirm ...
Roberto Gangemi   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy