Results 251 to 257 of about 80,628 (257)

Trending Fibrinolytic Dysregulation: Fibrinolysis Shutdown in the Days After Injury Is Associated With Poor Outcome in Severely Injured Children

Annals of Surgery, 2017
Objective: To trend fibrinolysis after injury and determine the influence of traumatic brain injury (TBI) and massive transfusion on fibrinolysis status.
Christine M. Leeper, M. Neal, Christine McKenna, B. Gaines   +3 more
semanticscholar   +1 more source

Model of trauma-induced coagulopathy including hemodilution, fibrinolysis, acidosis, and hypothermia: Impact on blood coagulation and platelet function

Journal of Trauma and Acute Care Surgery, 2017
BACKGROUND Trauma-induced coagulopathy (TIC) is commonly seen among patients with severe injury. The dynamic process of TIC is characterized by variability of the features of the disease. METHODS A model of TIC was created.
B. Shenkman, I. Budnik, Y. Einav, H. Hauschner, Mykhaylo Andrejchin, U. Martinowitz   +5 more
semanticscholar   +1 more source

Fibrinolysis in Trauma: “Myth,” “Reality,” or “Something in Between”

Seminars in Thrombosis and Hemostasis, 2017
The emphasis on fibrinolysis as an important contributor to trauma-induced coagulopathy (TIC) has led to a debate regarding the relative clinical significance of fibrinolysis in the setting of trauma. The debate has centered on two camps.
M. Walsh, Jacob Shreve, S. Thomas, E. Moore, H. Moore, D. Hake, T. Pohlman, Patrick K. Davis, V. Ploplis, Andres S. Piscoya, J. Wegner, John Bryant, Anton Crepinsek, James Lantry, F. Sheppard, F. Castellino   +15 more
semanticscholar   +1 more source

Asthma is associated with enhanced thrombin formation and impaired fibrinolysis

Clinical and Experimental Allergy, 2016
There is evidence that altered blood coagulation and fibrinolysis are involved in the pathogenesis of asthma. Increased thromboembolic risk has been reported in asthmatics.
S. Bazan-Socha, L. Mastalerz, Agnieszka Cybulska, L. Zarȩba, R. Kremers, M. Ząbczyk, G. Pulka, T. Iwaniec, C. Hemker, A. Undas   +9 more
semanticscholar   +1 more source

Featured Articles for CME Credit December 2014 Hyperfibrinolysis, physiologic fibrinolysis, and fibrinolysis shutdown: The spectrum of postinjury fibrinolysis and relevance to antifibrinolytic therapy

, 2014
Impact Statement: Death from hemorrhage remains the leading cause of preventable death from trauma. One in three severely injured patients presents to the hospital with trauma-induced coagulopathy (TIC).
H. Moore, E. Moore, E. Gonzalez, M. Chapman, T. Chin, C. Silliman, A. Banerjee, A. Sauaia, Sarah B. Bryczkowski, Maeve C. Lopreiato, Peter P. Yonclas, James J. Sacca, A. Mosenthal   +12 more
semanticscholar   +1 more source

The role of plasminogen activators in stroke treatment: fibrinolysis and beyond

Lancet Neurology, 2018
Audrey M Thiebaut, M. Gauberti, C. Ali, S. M. D. Lizarrondo, D. Vivien, M. Yepes, Benoit D Roussel   +6 more
semanticscholar   +1 more source

Fibrinolysis in trauma: a review

European Journal of Trauma and Emergency Surgery, 2018
M. Madurska, K. Sachse, Jan O. Jansen, Todd E. Rasmussen, J. Morrison   +4 more
semanticscholar   +1 more source