Results 51 to 60 of about 24,629 (256)

Mechanical Stability and Fibrinolytic Resistance of Clots Containing Fibrin, DNA, and Histones [PDF]

, 2013
Neutrophil extracellular traps are networks of DNA and associated proteins produced by nucleosome release from activated neutrophils in response to infection stimuli and have recently been identified as key mediators between innate immunity, inflammation,
Ammollo, Aziz, Borissoff, Brill, Brinkmann, Clark, Esmon, Esmon, Fuchs, Fuchs, Gladysheva, Gleber, Guthold, Komissarov, Komorowicz, Longstaff, Longstaff, Massberg, Nikolova, Rocha, Ruf, Ryan, Rábai, Rácz, Saha, Sands, Scrutton, Semeraro, Silva, Smeeth, Walker, Weisel, Weisel, Wohner, Xu, Yang, Yeromonahos   +36 more
core   +1 more source

ROS‐induced modifications of fibrin clots connect immune responses to atherothrombosis in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Cardiovascular events are major determinants of morbidity and mortality in systemic lupus erythematosus (SLE), particularly in patients with renal involvement. While oxidative stress has been implicated in driving vascular and renal damage in SLE, the specific mechanisms remain unclear.
Matteo Becatti, Giacomo Emmi, Alessandra Bettiol, Amanda Mannucci, Flavia Rita Argento, Eleonora Fini, Serena Borghi, Francesca Nencini, Maria Nicastro, Irene Mattioli, Elena Silvestri, Augusto Vaglio, Domenico Prisco, Claudia Fiorillo   +13 more
wiley   +1 more source

Percutaneous management of complicated parapneumonic effusion and empyema after surgical tube thoracostomy failure in children: a retrospective study

Diagnostic and Interventional Radiology, 2021
PurposeWe aimed to evaluate the results of percutaneous management of complicated parapneumonic effusions (PPE) and empyema after surgical tube thoracostomy failure in children.MethodsA total of 84 children treated percutaneously after surgical tube ...
Turkmen Turan Ciftci, Devrim Akinci, Emre Unal, Gonul Tanır, Hakan Artas, Okan Akhan   +5 more
doaj   +1 more source

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

Barrier Immunity, EarlyView.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia, Mathias Hochgerner, Qingzhen Wei, Xian'ge Zhong, Jiucun Wang   +4 more
wiley   +1 more source

Purification and Characterisation of a Fibrinolytic Enzyme from Rhizopus micro sporus var. tuberosus

Food Technology and Biotechnology, 2015
Extracellular fibrinolytic enzyme from Rhizopus microsporus var. tuberosus was purified and characterised. The microorganism was isolated in a distillery from daqu, a fermentative agent used in the production of Chinese liquor and vinegar at diff erent ...
Shuli Zhang, Yingdong Wang, Nan Zhang, Zhe Sun, Yan Shi, Xingnan Cao, Haikuan Wang   +6 more
doaj   +1 more source

In vivo performance of antibiotic embedded electrospun PCL membranes for prevention of abdominal adhesions [PDF]

, 2007
The aim of this study was to prepare nonwoven materials from poly(-caprolactone) (PCL) and their antibiotic containing forms by electrospinning, so as to prevent postsurgery induced abdominal adhesions in rats. -Caprolactone was first polymerized by ring-
Bolgen , Nimet, Bölgen , Nimet, Korkusuz, P., Menceloglu, Yusuf Z., Menceloğlu, Yusuf Z., Piskin, Erhan, Pişkin, Erhan, Vargel, İ., Vargel, I.   +8 more
core   +1 more source

Effects of immune checkpoint inhibitors on the pulmonary circulation in lung cancer patients

International Journal of Cancer, EarlyView.
What's New? Immune checkpoint inhibitors (ICIs) are effective against various cancers, but as more patients receive these therapies, more immune‐related adverse events (irAEs) emerge. Recent studies have suggested that ICIs are associated with an increase in pulmonary artery diameter and the ratio between pulmonary artery diameter and aortic diameter ...
Yao Xu, Qiuhong Zhang, Jie Gao, Shiyuan Yao, Chan Tian, Tuo He, Ming Zhang, Hu Shan, Jie Shi, Bo Yuan, Lei Wang, Xia Yang   +11 more
wiley   +1 more source

Effect of the administration of recombinant hirudin and/or tissue-plasminogen activator (t-PA) on endotoxin-induced disseminated intravascular coagulation model in rabbits [PDF]

, 1999
We evaluated the effect of r-hirudin and/or tissue-plasminogen activator (t-PA) in a model of DIC in rabbits induced by i.v. infusion of 100 micrograms/kg/h/6 h endotoxin. Rabbits were treated with saline (endotoxin control group), r-hirudin at 0.3 mg/kg/
Hermida, J. (José), Montes, R. (Ramón), Muñoz, M.C. (María Carmen), Orbe, J. (Josune), Paramo, J.A. (José Antonio), Rocha, E. (Eduardo)   +5 more
core   +1 more source

Safety and efficacy of enoxaparin versus unfractionated heparins in conservatively managed patients with acute coronary syndrome: a systematic review

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Aim Guidelines recommend initial anticoagulant management of acute coronary syndrome (ACS) with low molecular weight heparin (LMWH) such as enoxaparin or unfractionated heparin (UFH). Systematic reviews evaluate early trials in the context of multiple other medications or during percutaneous coronary intervention (PCI) only.
Krishna Doshi, Mark Jones, Laetitia Hattingh   +2 more
wiley   +1 more source

Plasminogen activators in acute management of thrombosis

Российский кардиологический журнал, 2013
The paper focuses on the problem of intravascular thrombosis and the methods of its treatment. The data on haemostasis pathophysiology, which underlie the occurrence of acute ischemic events in humans, are presented, together with the data on the action ...
E. O. Taratukhin
doaj   +1 more source