Results 221 to 230 of about 3,220,825 (277)
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Fibrinolytic Agents

2006
The fibrinolytic system plays a vital role in maintaining vital organ homeostasis. Fibrinolysis, defined as the dissolution of fibrin (the major scaffold for intravascular thrombus), is the process that regulates thrombus growth after hemostasis has been achieved, thus preserving tissue perfusion.
Richard C. Becker, Frederick A. Spencer
openaire   +1 more source

A study of the fibrin plate assay of fibrinolytic agents. Optimal conditions, reproducibility and precision.

Haemostasis, 1983
The reproducibility, precision and required conditions of the fibrin plate method for determination of fibrinolytic agents are described in detail. Under optimal conditions the assay is a sensitive and precise method for the quantitative determination of
J. Jespersen, T. Astrup
semanticscholar   +1 more source

Acyl-Enzymes As Fibrinolytic Agents [PDF]

open access: possibleThrombosis and Haemostasis, 1981
Plasminogen activators or plasmins specifically and reversibly acylated at the active centre have been used as delivery systems for fibrinolytic agents in vivo. Potential advantages of this approach, including enhanced efficacy, reduced toxicity and better control of lysis are discussed.
openaire   +1 more source

Intrapleural fibrinolytic agents for empyema and complicated parapneumonic effusions: a meta-analysis.

Chest, 2006
BACKGROUND Randomized controlled trials have shown conflicting findings about the role of intrapleural fibrinolytic therapy for the treatment of empyema and complicated parapneumonic effusions in adult patients.
Y. Tokuda   +3 more
semanticscholar   +1 more source

Pharmacology of fibrinolytic agents

Progress in Cardiovascular Diseases, 1979
T HE appreciation of the high morbidity and mortality from thromboembolic occlusive vascular disease has given the impetus to a continuing search for drugs that might be of clinical value in its prevention and treatment. Anticoagulant therapy with heparin or the oral anticoagulants is primarily prophylactic, and while these drugs can prevent the ...
openaire   +3 more sources

Comparison of Caseinolytic and Fibrinolytic Assays for Plasmin (Fibrinolysin) in “Fibrinolytic Agents”

Thrombosis and Haemostasis, 1966
Summary1. Caseinolytic and fibrinolytic systems for assay of plasmin in fibrinolytic agents are described which are based upon the determinations of AE/min during the linear portion of the casein-plasmin and fibrin-plasmin reaction curves respectively. A " caseinolytic-rate " unit and “fibrinolytic-rate " unit of ÄE/min × 103 during the linear portion ...
Mary Belle Frey, K. M Moser
openaire   +3 more sources

Tenecteplase: A promising new fibrinolytic agent

Dimensions of Critical Care Nursing, 2001
Acute coronary syndrome can mean anything from unstable angina to acute myocardial infarction (MI) with ST-segment elevation. Tenecteplase, a new fibrinolytic agent used to treat ST-segment elevation acute MI, has some advantages over other fibrinolytic agents. This article describes tenecteplase's actions, indications, contraindications, and use.
Sabadie-Garretson W, De Jong Mj
openaire   +3 more sources

Antibody-Directed Urokinase: A Specific Fibrinolytic Agent [PDF]

open access: possibleScience, 1985
A specific fibrinolytic agent was synthesized by covalently coupling urokinase to a monoclonal antibody that was fibrin-specific and did not cross-react with fibrinogen. The antibody was raised against a synthetic peptide representing the seven amino-terminal residues of the beta chain of human fibrin.
Kwan Y. Hui   +3 more
openaire   +2 more sources

Thrombelastographic patterns produced by fibrinolytic agents incorporated in fibrin.

American Journal of Physiology, 1965
Lysis of clots produced from bovine fibrinogen and bovine thrombin in the presence of fibrinolytic agents was followed by thrombelastography in order to obtain information about the mechanism of clot lysis in a standardized, purified system, which ...
T. Astrup, K. Egeblad
semanticscholar   +1 more source

Tenecteplase: A fibrinolytic agent

British Journal of Cardiac Nursing, 2006
Thrombolysis is an established therapy for acute myocardial infarction in the UK. ST-elevation myocardial infarction almost always occurs owing to coronary atherosclerosis and coronary thrombosis which develops because of plaque disruption. Fibrinolytic agents act to dissolve the clot.
openaire   +2 more sources

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