Results 51 to 60 of about 799,312 (331)

Presence and localization of a 30-kDa basic fibroblast growth factor-like protein in rodent testes [PDF]

, 1991
We have used a recently characterized rabbit antiserum against basic fibroblast growth factor (bFGF), which recognizes various forms of bFGF, to examine the presence and localization of bFGF in the testes of adult rats and mice and the 5-day-old rat.
Gratzl, Manfred, Grothe, C., Mayerhofer, Artur, Rudolf, M., Russell, J. T.   +4 more
core   +1 more source

Atractylenolide-I Sensitizes Triple-Negative Breast Cancer Cells to Paclitaxel by Blocking CTGF Expression and Fibroblast Activation

Frontiers in Oncology, 2021
This investigation was conducted to elucidate whether atractylenolide-I (ATL-1), which is the main component of Atractylodes macrocephala Koidz, can sensitize triple-negative breast cancer (TNBC) cells to paclitaxel and investigate the possible mechanism
Meng Wang, Xue-Zhen Li, Ming-Xing Zhang, Qian-Yu Ye, Ying-Xia Chen, Xu Chang   +5 more
doaj   +1 more source

Fibroblast mediated dynamics in diffusively uncoupled myocytes -- a simulation study using 2-cell motifs [PDF]

arXiv, 2023
In healthy hearts myocytes are typically coupled to nearest neighbours through gap junctions. Under pathological conditions such as fibrosis, or in scar tissue, or across ablation lines myocytes can uncouple from their neighbours. Electrical conduction may still occur via fibroblasts that not only couple proximal myocytes but can also couple otherwise ...
arxiv  

Extinction of gene expression in somatic cell hybrids. a reflection of important regulatory mechanisms? [PDF]

, 1993
Extinction in somatic cell hybrids is a multifactorial process that leads to loss of cell-type-specific gene expression. The underlying mechanisms are thought to mirror, at least in part, the repertoire of regulatory mechanisms controlling mammalian cell
Boshart, Michael, Nitsch, Doris, Schütz, Günther   +2 more
core   +1 more source

Seprase: An overview of an important matrix serine protease [PDF]

, 2008
Seprase or Fibroblast Activation Protein (FAP) is an integral membrane serine peptidase, which has been shown to have gelatinase activity. Seprase has a dual function in tumour progression.
Abbott, Abbott, Abbott, Acharya, Adams, Adams, Aertgeerts, Aimes, Alcolado, Aoyama, Ariga, Artym, Bangert, Barrett, Bauvois, Bermpohl, Birney, Bissell, Brendan F. O'Connor, Brown, Busek, Chen, Chen, Chen, Chen, Cheng, Cheng, Christiansen, Collins, Corpet, De Wever, Del Rosso, Dolznig, Dvorak, Edosada, Edosada, Fassnacht, Fidler, Fink, Flentke, Fulop, Garcia-Horsman, Garin-Chesa, Gerner, Ghersi, Ghersi, Ghersi, Gilmore, Goldstein, Goldstein, Goodman, Gorrell, Guex, Hofheinz, Huang, Huber, Huber, Ibrahim, Iwasa, Jin, Kelly, Kelly, Kelly, Kelly, Kloft, Koyama, Lee, Lee, Lee, Lee, Lee, Levy, Levy, Levy, Loeffler, Mathew, Mersmann, Milner, Monsky, Mori, Mueller, Nicholas, Niedermeyer, Niedermeyer, Niedermeyer, Oertel, Okada, Okada, Ollis, Pamela O'Brien, Park, Pineiro-Sanchez, Ramirez-Montagut, Rennex, Rettig, Rettig, Rettig, Rettig, Rosenblum, Samel, Scanlan, Schechter, Scott, Scott, Sieweke, Skubitz, Stremenova, Sun, Tahtis, Tran, Wang, Wang, Welt, Welt, Wesley, Zhang   +115 more
core   +1 more source

Endoplasmic Reticulum Stress Activation in Alport Syndrome Varies Between Genotype and Cell Type

Frontiers in Genetics, 2020
Alport syndrome is a hereditary progressive chronic kidney disease caused by mutations in type IV collagen genes COL4A3/4/5. X-linked Alport syndrome (XLAS) is caused by mutations in the COL4A5 gene and is the most common form of Alport syndrome.
Cong Wang, Shenghui Liang, Shijia Xing, Ke Xu, Huijie Xiao, Haiyue Deng, Xiaoyuan Wang, Liangyi Chen, Jie Ding, Fang Wang   +9 more
doaj   +1 more source

Stromal cells differentially regulate neutrophil and lymphocyte recruitment through the endothelium [PDF]

, 2010
Stromal fibroblasts modify the initial recruitment of leucocytes by endothelial cells (EC), but their effects on subsequent transendothelial migration remain unclear.
Arisaka, Balashov, Bijuklic, Bradfield, Brezinschek, Buckley, Burger, Burman, Butler, Buttrum, Carlos, Chakravorty, Chappell, Cinamon, Cinamon, Colditz, Cooke, Covas, Crisan, Curbishley, Denton, Dore-Duffy, Edwards, Fedyk, Filer, Firestein, Goddard, Hardingham, Holt, Khandoga, Koch, Kunz-Schughart, Lally, Ley, Li, Liu, Luscinskas, Luu, Luu, Martin, McGettrick, McGettrick, McGettrick, Middleton, Mohan, Mul, Nanki, Oberringer, Oppenheimer-Marks, Pablos, Piali, Pietschmann, Proost, Pruenster, Rainger, Rainger, Rajkumar, Ranjbaran, Ransohoff, Salmon, Shamri, Shiwen, Shulman, Sims, Smith, Sorrell, Szczepanek, Taylor, Traktuev, Tull, Ueno, Van Lint, Wang   +72 more
core   +2 more sources

A redox-responsive hyaluronic acid-based hydrogel for chronic wound management [PDF]

, 2021
Polymer-based hydrogels have been widely applied for chronic wound therapeutics, due to their well-acclaimed wound exudate management capability. At the same time, there is still an unmet clinical need for simple wound diagnostic tools to assist clinical decision-making at the point of care and deliver on the vision of patient-personalised wound ...
arxiv   +1 more source

Identification and characterization of an inhibitory fibroblast growth factor receptor 2 (FGFR2) molecule, up-regulated in an Apert Syndrome mouse model [PDF]

, 2011
AS (Apert syndrome) is a congenital disease composed of skeletal, visceral and neural abnormalities, caused by dominant-acting mutations in FGFR2 [FGF (fibroblast growth factor) receptor 2].
Anderson, Beenken, Bochukova, Burgar, Celli, Cohen, De Moerlooze, Duan, Duchesne, Ezzat, Fairbanks, Hajihosseini, Hajihosseini, Hajihosseini, Hajihosseini, Hajihosseini, Hanneken, Ibrahimi, Jang, Jang, Jang, John K. Heath, Jones, Kawano, Klein, Kuro-o, Lee M. Wheldon, Lewis, Maquat, McKeehan, Mendell, Meyers, Miki, Mohammad K. Hajihosseini, Muhlemann, Naila Khodabukus, Naski, Nelson, Oldridge, Peters, Polanska, Ricol, Saito, Sekine, Slaney, Smith, Susannah J. Patey, Takaishi, Tanimoto, Terada, Terence G. Smith, Tsang, Tsukuno, Werner, Wheldon, Wilkie, Yamaguchi, Zhang   +57 more
core   +3 more sources

An acidic fibroblast growth factor protein generated by alternate splicing acts like an antagonist. [PDF]

, 1992
Polymerase chain reaction amplification of cDNA for acidic fibroblast growth factor in several lines of cultured human cells revealed two forms of mRNA.
Goetzl, EJ, Golden, JA, Kha, H, Migchielsen, AA, Turck, CW, Yu, YL   +5 more
core