Results 261 to 270 of about 1,957,077 (351)

Integrative transcriptomic analysis reveals interferon-associated macrophage states and fibroblast activation in hypertrophic cardiomyopathy

Bo Li, Jiarui Wang, Jian Shen
openalex   +1 more source

Kidney fibrosis is mediated by GARP-restricted TGF-β activation in fibroblasts [PDF]

Yu Chen, Weiwei Xu, Jieli Yu, Pei Deng, Nianping Liu, Yinyin Li, Hui Zhou, Hong Zhou, Jianchuan Wang, Bo Zhao, Florian Winau, Fan Fan Hou, Yu Hu   +12 more
openalex   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Tuning the Structural Properties of a Single-Domain Antibody Scaffold for Improved Fibroblast Activation Protein Targeting. [PDF]

Mol Pharm
Gallant JP, Ott KL, Kwon O, Adeniyi A, Barrett KE, Rosenkrans ZT, Mixdorf JC, Aluicio-Sarduy E, Engle JW, Hernandez R, Bednarz BP, LeBeau AM.   +11 more
europepmc   +1 more source

Hyaluronan Synthase Isoforms Direct Distinct Patterns of Fibroblast Activation Linked to Fibrosis Progression Versus Resolution Following Renal Ischaemia

Irina V. Grigorieva, Adam C. Midgley, Charlotte Brown, Gilda Pino‐Chavez, Barbara Szomolay, Aled Williams, Rachel DePaul, Richard James Stanton, John M. Hancock, Timothy Bowen, Deva D. Chan, Anna Plaas, Rafael Chavez, Robert Steadman, Usman Khalid, Soma Meran   +15 more
openalex   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Correction: Embryo-derive TNF promotes decidualization via fibroblast activation.

Elife
Chen ST, Shi WW, Lin YQ, Yang ZS, Wang Y, Li MY, Li Y, Liu AX, Hu Y, Yang ZM.   +9 more
europepmc   +1 more source

STK25 inhibits cancer-associated fibroblast activation to overcome cetuximab resistance in colorectal cancer. [PDF]

Clin Transl Med
Hou Y, Chen J, Hao H, Song T, Song L, Xing P, Weng K, Ran Y, Yang X, Qiao X, Chen J, Yao R, Yang H, Chen L, Di J, Xu K, Su X, Jiang B.   +17 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source