Results 101 to 110 of about 547,171 (369)
Direct regulation of fibroblast growth factor 23 by energy intake through mTOR
Scientific Reports, 2020 To test the hypothesis that fibroblast growth factor 23 (FGF23) is directly regulated by energy intake, in vivo and in vitro experiments were conducted.
A. Vidal +7 more
semanticscholar +1 more source
Pathogenesis of FGF23-Related Hypophosphatemic Diseases Including X-linked Hypophosphatemia
Endocrines, 2022 Since phosphate is indispensable for skeletal mineralization, chronic hypophosphatemia causes rickets and osteomalacia. Fibroblast growth factor 23 (FGF23), which is mainly produced by osteocytes in bone, functions as the central regulator of phosphate ...
Tatsuro Nakanishi, Toshimi Michigami
doaj +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Simulations demonstrate a simple network to be sufficient to control branch point selection, smooth muscle and vasculature formation during lung branching morphogenesis [PDF]
G. Celli\`ere, D Menshykau and Dagmar Iber (2012) Biology Open 1,
775-788, 2012 Proper lung functioning requires not only a correct structure of the conducting airway tree, but also the simultaneous development of smooth muscles and vasculature. Lung branching morphogenesis is strongly stereotyped and involves the recursive use of only three modes of branching.
arxiv +1 more source
European Journal of Heart Failure, 2020 Fibroblast growth factor 23 (FGF23) is an intensively studied biomarker at the crossroads of cardiovascular disease, heart failure (HF) and chronic kidney disease.
R. Stöhr +9 more
semanticscholar +1 more source
Secondary Hyperparathyroidism in chronic kidney disease patients; current knowledge [PDF]
, 2006 When renal function diminishes, secondary hyperparathyroidism with develop in response to worsening of kidney function and declined phosphate excretion (1).
Amiri, M., Nasri, H.
core
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
A modeling approach to study the effect of cell polarization on keratinocyte migration [PDF]
PLoS ONE. 2015;10(2):e0117676, 2015 The skin forms an efficient barrier against the environment, and rapid cutaneous wound healing after injury is therefore essential. Healing of the uppermost layer of the skin, the epidermis, involves collective migration of keratinocytes, which requires coordinated polarization of the cells.
arxiv +1 more source
Fibroblast Growth Factor 23 (FGF23) and Disorders of Phosphate Metabolism [PDF]
, 2009 Derangements in serum phosphate level result in rickets/osteomalacia or ectopic calcification indicating that healthy people without these abnormalities maintain serum phosphate within certain ranges.
Fukumoto, Seiji, Saito, Tasuku
core +4 more sources
Fibroblast growth factor 23 and dietary factors in renal disease [PDF]
, 2015 Omega-3 poly-unsaturated fatty acids and mineral metabolism: novel therapy for cardiovascular disease in renal patients? Deregulations in mineral metabolism, particularly related to phosphate and its regulating hormone fibroblast growth factor 23 (FGF23),
da Cunha Baia, Leandro
core +6 more sources