Introduction It has been observed that intravenous iron administration may suppress endogenous production of erythropoietin (EPO). We postulate that this effect may be mediated by increased FGF-23 secretion.Aim of the study To evaluate the short-term ...
Katarzyna Muras-Szwedziak +2 more
doaj +1 more source
Predictors of intact and C-terminal fibroblast growth factor 23 in Gambian children [PDF]
Elevated C-terminal fibroblast growth factor 23 (C-FGF23) concentrations have been reported in Gambian children with and without putative Ca-deficiency rickets.
Assar, Shima +4 more
core +1 more source
Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications. [PDF]
Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival.
Helsten, Teresa +2 more
core +2 more sources
Osteocytes and the pathogenesis of hypophosphatemic rickets
Since phosphorus is a component of hydroxyapatite, its prolonged deprivation affects bone mineralization. Fibroblast growth factor 23 (FGF23) is essential for maintaining phosphate homeostasis and is mainly produced by osteocytes.
Miwa Yamazaki, Toshimi Michigami
doaj +1 more source
OR13-3 Effects of Iron Isomaltoside versus Ferric Carboxymaltose on Hormonal Control of Phosphate Homeostasis: The PHOSPHARE-IDA04/05 Randomized Controlled Trials [PDF]
Iron isomaltoside (IIM) and ferric carboxymaltose (FCM) are newer intravenous iron preparations that can be administered in high-doses to rapidly correct iron deficiency anemia (IDA).
Achebe, Maureen +9 more
core +1 more source
Fibroblast Growth Factor-23 and Outcomes [PDF]
Even after taking into account comorbidities, such as a diabetes and hypertension, that often accompany CKD, patients are plagued by a high risk of early mortality, particularly because of cardiovascular disease (CVD).[1][1] Focus on traditional risk factors from the general population, such ...
Ishir, Bhan, Ravi, Thadhani
openaire +2 more sources
PKC regulates the production of fibroblast growth factor 23 (FGF23).
Serine/threonine protein kinase C (PKC) is activated by diacylglycerol that is released from membrane lipids by phospholipase C in response to activation of G protein-coupled receptors or receptor tyrosine kinases.
Ludmilla Bär +2 more
doaj +1 more source
Intravenous phosphate loading increases fibroblast growth factor 23 in uremic rats. [PDF]
Oral phosphate loading and calcitriol stimulate Fibroblast growth factor 23 (FGF23) secretion, but the mechanisms underlying the stimulation of FGF23 remain to be studied.
Noriko Arai-Nunota +10 more
doaj +1 more source
Association of Fibroblast Growth Factor 23 and Calcium in Chronic Kidney Disease Patients
Chronic kidney disease (CKD) is a growing international health concern with elevating mortality rate in the world today and it is generally a progressive and irreversible issue.
Ghaith Hamza Kamil +2 more
doaj +1 more source
A two-compartment mechanochemical model of the roles of\ud transforming growth factor β and tissue tension in dermal wound healing [PDF]
The repair of dermal tissue is a complex process of interconnected phenomena, where cellular, chemical and mechanical aspects all play a role, both in an autocrine and in a paracrine fashion.
Hall, C. L. +4 more
core +3 more sources

