Results 151 to 160 of about 553,087 (356)

Fibroblast growth factor signaling in macrophage polarization: impact on health and diseases

Frontiers in Immunology
Fibroblast growth factors (FGFs) are a versatile family of peptide growth factors that are involved in various biological functions, including cell growth and differentiation, embryonic development, angiogenesis, and metabolism. Abnormal FGF/FGF receptor
Luyao Shen, Yongsheng Li, Yongsheng Li, Huakan Zhao   +3 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Urine fibroblast growth factor 23 levels in hypertensive children and adolescents [PDF]

, 2015
M Zając, Agnieszka Rybi–Szumińska, Anna Wasilewska   +2 more
openalex   +1 more source

Fibroblast Growth Factor 21 Predicts Short-Term Prognosis in Patients With Acute Heart Failure: A Prospective Cohort Study

, 2022
Guihai Wu, Shenglin Wu, Jingyi Yan, Shanshan Gao, Jinxiu Zhu, Minghui Yue, Zexin Li, Xuerui Tan   +7 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Correction to: Fibroblast growth factor receptor 3 alterations and response to immune checkpoint inhibition in metastatic urothelial cancer: a real world experience [PDF]

, 2022
Tracy L. Rose, William H. Weir, Gregory M. Mayhew, Yoichiro Shibata, Patrick Eulitt, Joshua M. Uronis, Mi Zhou, Matthew E. Nielsen, Angela B. Smith, Michael Woods, Michele C. Hayward, Ashley H. Salazar, Matthew I. Milowsky, Sara E. Wobker, Katrina McGinty, Michael V. Millburn, Joel R. Eisner, William Y. Kim   +17 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Assessment of serum and salivary malondialdehyde in patients with oral lichen planus

Journal of Baghdad College of Dentistry, 2014
Background: The aim of this study was to evaluate the expression of fibroblast growth factor-2 and Heparanase in salivary pleomorphic adenoma, and to correlate the two studied markers with each other and with clinicopathological parameters including: age,
Aws W Abbas, Taghreed F Zaidan, Abduladheem Y Al-Barrak   +2 more
doaj  

FGFs/FGFRs and neuroinflammatory diseases: mechanism, drug therapies and delivery systems

Journal of Advanced Research
Background: Fibroblast Growth Factors and Fibroblast Growth Factor Receptors (FGFs/FGFRs) constitute a complex and diverse signaling system crucial in various biological processes, such as cell proliferation, differentiation, migration, and survival ...
Juan Wang, Lijuan Xing, Yang Song, Yue Yang, Yinzhuo Zhang, Haoxiang Ma, Benyu Su, Luoxuan Su, Chao Ma, Mingyan Liu, Ke Du   +10 more
doaj   +1 more source

The influence of transforming growth factor β, epidermal growth factor and insulin on DNA biosynthesis in mouse fibroblasts of swiss-3T3 line grown in monolayer cultures with low and high cell density [PDF]

, 1992
Rostyslav Stoika, S. I. Sushelnitsky, S I Kusen   +2 more
openalex   +1 more source