Results 221 to 230 of about 352,093 (306)

Fibroblast Growth Factor-Derived Peptides: Sources, Functions, and Applications. [PDF]

Bioengineering (Basel)
Cao CK, Shi ZY, Chen CB, Li XK, Su ZJ.
europepmc   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

Advanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min, Nam Than, Yong Cheol Shin, Elif G. Ertugral, Chandrasekhar R. Kothapalli, Olumuyiwa Awoniyi, Hyun Jung Kim   +6 more
wiley   +1 more source

Fibroblast Growth Factor 23 as a Prognostic Biomarker in Post-Myocardial Infarction Outcomes: Influence of Renal Function and Its Modulation by Klotho. [PDF]

J Am Heart Assoc
Vázquez-Sánchez S, Blasco A, Polo-Salguero M, Mourino-Álvarez L, Gil-Fernández M, Corbacho-Alonso N, Navarro-García JA, Mercado-García E, González-Lafuente L, Rodríguez-Sánchez E, González-Moreno D, Pérez-Gómez A, Matutano A, Vázquez J, López JA, Fernández-Velasco M, Barderas MG, Ruiz-Hurtado G.   +17 more
europepmc   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Changes in fibroblast growth factor 21 levels associated with alcohol consumption and smoking cessation. [PDF]

Endocr Connect
Sailer CO, Vogel CF, Monnerat S, Probst L, Christ-Crain M, Winzeler B, Refardt J.   +6 more
europepmc   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source

Circulating Fibroblast Growth Factor 21 (FGF21) as a Prognostic and Diagnostic Biomarker in Hepatocellular Carcinoma. [PDF]

J Hepatocell Carcinoma
Eid JR, Yalciner M, Xiao L, Sun R, Kannan MK, Hassan M, Rashid A, Chamseddine S, Tran Cao HS, Amin HM, Kaseb AO.   +10 more
europepmc   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Fibroblast growth factor signals drive the metastatic behavior in small cell lung cancer. [PDF]

Br J Cancer
Ernhofer B, Solta A, Sinner J, Megyesfalvi Z, Deloria AJ, Boettiger K, Glatt L, Horvath L, Sturtzel C, Wenninger-Weinzierl A, Distel M, Grusch M, Szeitz B, Rezeli M, Aigner C, Dome B, Schelch K.   +16 more
europepmc   +1 more source