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Fibroblast Growth Factor Prototype Release and Fibroblast Growth Factor Receptor Signaling
Thrombosis and Haemostasis, 1999A Brief Introduction to the Fibroblast Growth Factor Gene Family The fibroblast growth factor (FGF) family of genes presently comprise 18 members, including the two prototypes, FGF-1 (acidic) and FGF-2 (basic). Although the FGF prototypes are well described as mediators of a variety of diverse biological responses, such as mesoderm induction ...
R, Friesel, T, Maciag
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Differentiation
Fibroblast growth factor 22 (FGF22) is a member of the FGF7 subfamily that functions as a paracrine factor and was identified in the human placenta in 2001. The FGF22 gene is located on human chromosome 19p13.3, mouse chromosome 10, and zebrafish chromosome 22 and is closely linked to the BSG, HCN2, and POLRMT genes. The gene is composed of three exons,
Rise, Furuta, Ayumi, Miyake
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Fibroblast growth factor 22 (FGF22) is a member of the FGF7 subfamily that functions as a paracrine factor and was identified in the human placenta in 2001. The FGF22 gene is located on human chromosome 19p13.3, mouse chromosome 10, and zebrafish chromosome 22 and is closely linked to the BSG, HCN2, and POLRMT genes. The gene is composed of three exons,
Rise, Furuta, Ayumi, Miyake
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Differentiation
Fibroblast growth factor 21 (FGF21) belongs to the FGF19 subfamily and acts systemically, playing a key role in inter-organ crosstalk. Ranging from metabolism, reproduction, and immunity, FGF21 is a pleiotropic hormone which contributes to various physiological processes.
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Fibroblast growth factor 21 (FGF21) belongs to the FGF19 subfamily and acts systemically, playing a key role in inter-organ crosstalk. Ranging from metabolism, reproduction, and immunity, FGF21 is a pleiotropic hormone which contributes to various physiological processes.
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Fibroblast growth factor signalling in osteoarthritis and cartilage repair
Nature Reviews Rheumatology, 2020Yang-Li Xie +3 more
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Fibroblast growth factor signalling: from development to cancer
Nature Reviews. Cancer, 2010N. Turner, R. Grose
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Thrombin inactivates acidic fibroblast growth factor but not basic fibroblast growth factor
Biochemistry, 1988Incubation of bovine brain derived acidic fibroblast growth factor (aFGF) with bovine or human thrombin, 0.5 NIH unit/mL, for 24 h at 37 degrees C results in cleavage of the mitogen, generating a 14-kilodalton fragment which has significantly reduced affinity for immobilized heparin as compared to aFGF, and is at least 50-fold less potent at ...
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Cellular signaling by fibroblast growth factor receptors.
Cytokine & growth factor reviews, 2005Veraragavan P. Eswarakumar +2 more
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Metabolic Messengers: fibroblast growth factor 15/19
Nature Metabolism, 2019R. Gadaleta, A. Moschetta
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