Results 61 to 70 of about 514,253 (261)
Transforming growth factor-beta stimulation of lung fibroblast prostaglandin E2 production. [PDF]
, 1989 Transforming growth factor-beta (TGF beta) stimulated the production of total protein, collagen, and fibronectin by normal human lung fibroblasts.
Diaz, Arturo +2 more
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Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications. [PDF]
, 2015 Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival.
Helsten, Teresa +2 more
core +2 more sources
Fibroblast growth factor 19 stimulates water intake
Molecular Metabolism, 2022 Fibroblast growth factor 19 (FGF19) is a hormone with pleiotropic metabolic functions, leading to ongoing development of analogues for treatment of metabolic disorders. On the other hand, FGF19 is overexpressed in a sub-group of hepatocellular carcinoma (
José Ursic-Bedoya +9 more
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Fibroblast growth factor receptor 4 single nucleotide polymorphism Gly388Arg in head and neck carcinomas [PDF]
, 2019 BACKGROUND Head and neck squamous cell carcinoma (HNSCC) is considered to be a progressive disease resulting from alterations in multiple genes regulating cell proliferation and differentiation like receptor tyrosine kinases (RTKs) and members of the ...
Bergmann, C. +5 more
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Computer-assisted stabilization of fibroblast growth factor FGF-18
Computational and Structural Biotechnology Journal, 2023 The fibroblast growth factors (FGF) family holds significant potential for addressing chronic diseases. Specifically, recombinant FGF18 shows promise in treating osteoarthritis by stimulating cartilage formation.
Jan Vilim +8 more
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Journal of Translational Medicine, 2020 Background Conotruncal defects (CTDs) are a type of heterogeneous congenital heart diseases (CHDs), but little is known about their etiology. Increasing evidence has demonstrated that fibroblast growth factor (FGF) 8 and FGF10 may be involved in the ...
Kun Sun +8 more
doaj +1 more source
Growth factors for clinical-scale expansion of human articular chondrocytes : Relevance for automated bioreactor systems [PDF]
, 2007 The expansion of chondrocytes in automated bioreactors for clinical use requires that a relevant number of cells be generated, starting from variable initial seeding densities in one passage and using autologous serum.
Andrea Barbero +12 more
core +1 more source
The Fibroblast Growth Factor signaling pathway [PDF]
WIREs Developmental Biology, 2015 The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF receptors (FGFRs). Interaction of FGF ligands with their signaling receptors is regulated by protein or proteoglycan cofactors and by extracellular binding proteins.
David M. Ornitz, Nobuyuki Itoh
openaire +3 more sources
The Role of Fibroblast Growth Factors in Tumor Growth [PDF]
Current Cancer Drug Targets, 2009 Biological processes that drive cell growth are exciting targets for cancer therapy. The fibroblast growth factor (FGF) signaling network plays a ubiquitous role in normal cell growth, survival, differentiation, and angiogenesis, but has also been implicated in tumor development.
Robert Friesel, Murray Korc
openaire +3 more sources
Open Access Rheumatology: Research and Reviews, 2009 Hee-Jeong Im,1–4 Andrew D Sharrocks,5 Xia Lin,6 Dongyao Yan,1 Jaesung Kim,1 Andre J van Wijnen,7 Robert A Hipskind81Departments of Biochemistry, 2Internal Medicine, 3Section of Rheumatology, Orthopedic Surgery, 4Rush University Medical Center ...
Hee-Jeong Im +3 more
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