Results 11 to 20 of about 78,520,259 (248)

Vagal-α7nAChR signaling promotes lung stem cells regeneration via fibroblast growth factor 10 during lung injury repair [PDF]

Stem Cell Research & Therapy, 2020
Background Proliferation and transdifferentiation of lung stem cells (LSCs) could promote lung injury repair. The distal airways of the lung are innervated by the vagus nerve.
Xiaoyan Chen, Caiqi Zhao, Cuiping Zhang, Qingmei Li, Jie Chen, Lianping Cheng, Jian Zhou, Xiao Su, Yuanlin Song   +8 more
doaj   +2 more sources

Role of Fibroblast Growth Factor 10 in Mesenchymal Cell Differentiation During Lung Development and Disease [PDF]

Frontiers in Genetics, 2018
During organogenesis and pathogenesis, fibroblast growth factor 10 (Fgf10) regulates mesenchymal cell differentiation in the lung. Different cell types reside in the developing lung mesenchyme. Lineage tracing in vivo was used to characterize these cells
Jin Wu, Xuran Chu, Xuran Chu, Chengshui Chen, Saverio Bellusci, Saverio Bellusci, Saverio Bellusci   +6 more
doaj   +2 more sources

RNA-Seq explores the functional role of the fibroblast growth factor 10 gene in bovine adipocytes differentiation [PDF]

Animal Bioscience
Objective The present study was executed to explore the molecular mechanism of fibroblast growth factor 10 (FGF10) gene in bovine adipogenesis. Methods The bovine FGF10 gene was overexpressed through Ad-FGF10 or inhibited through siFGF10 and their ...
Nurgulsim Kaster, Rajwali Khan, Ijaz Ahmad, Kazhgaliyev Nurlybay Zhigerbayevich, Imbay Seisembay, Akhmetbekov Nurbolat, Shaikenova Kymbat Hamitovna, Omarova Karlygash Mirambekovna, Makhanbetova Aizhan Bekbolatovna, Tlegen Garipovich Amangaliyev, Ateikhan Bolatbek, Titanov Zhanat Yeginbaevich, Shakoor Ahmad, Zan Linsen, Begenova Ainagul Baibolsynovna   +14 more
doaj   +2 more sources

Cross-Talk Between Inflammation and Fibroblast Growth Factor 10 During Organogenesis and Pathogenesis: Lessons Learnt From the Lung and Other Organs [PDF]

Frontiers in Cell and Developmental Biology, 2021
The adult human lung is constantly exposed to irritants like particulate matter, toxic chemical compounds, and biological agents (bacteria and viruses) present in the external environment.
Manuela Marega, Manuela Marega, Chengshui Chen, Saverio Bellusci, Saverio Bellusci   +4 more
doaj   +2 more sources

Roll with the punches: Fibroblast growth factor 10 alleviates pyroptosis of alveolar epithelial cells in different immune niches [PDF]

Clinical and Translational Medicine
Background Acute respiratory distress syndrome (ARDS) is a life‐threatening condition characterized by high mortality with no specific treatments. Fibroblast growth factor 10 (FGF10) is recognized for its tissue repair and anti‐inflammatory roles in ...
Tianchang Wei, Xiaoyan Chen, Jian Xu, Weiqi Mao, Zhenlin Yang, Yuhan Wang, Yufan Li, Wenting Jin, Cuicui Chen, Cuiping Zhang, Yuanlin Song   +10 more
doaj   +2 more sources

Expression and Clinical Significance of Novel Long Noncoding RNA Fibroblast Growth Factor 10AS and FGF10 in Colorectal Cancer [PDF]

Cell Journal, 2021
Objective: Colorectal cancer (CRC) imposes great health burdens worldwide. Growth factors contribute to cell growth, differentiation, angiogenesis and, most importantly, tumour formation in many types of cancers.
Leili Rejali, Seyed Yoosef Seyedna, Hamid Asadzadeh Aghdaei, Ehsan Nazemalhosseini Mojarad, Mehrdad Hashemi   +4 more
doaj   +1 more source

Distinct effects of Fgf7 and Fgf10 on the terminal differentiation of murine bladder urothelium revealed using an organoid culture system

BMC Urology, 2023
Background Dysregulation of the terminal differentiation of bladder urothelium is associated with the pathogenesis of urinary tract disorders. Fibroblast growth factor (Fgf)7 and Fgf10 stimulate urothelial proliferation; however, their roles in cellular ...
Kazuto Suda, Yuka Matsumoto, Takanori Ochi, Hiroyuki Koga, Nobutaka Hattori, Atsuyuki Yamataka, Tetsuya Nakamura   +6 more
doaj   +1 more source

Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis. [PDF]

PLoS ONE, 2012
The signaling pathways that are essential for gastric organogenesis have been studied in some detail; however, those that regulate the maintenance of the gastric epithelium during adult homeostasis remain unclear.
Allison L Speer, Denise Al Alam, Frederic G Sala, Henri R Ford, Saverio Bellusci, Tracy C Grikscheit   +5 more
doaj   +1 more source

Myocardial protection by heparin-based coacervate of FGF10

Bioactive Materials, 2021
Heart disease is still the leading killer all around the world, and its incidence is expected to increase over the next decade. Previous reports have already shown the role of fibroblast growth factor10 (FGF10) in alleviating heart diseases.
Zhouguang Wang, Yan Huang, Yan He, Sinan Khor, Xingxing Zhong, Jian Xiao, Qingsong Ye, Xiaokun Li   +7 more
doaj   +1 more source

Mutations in fibroblast growth factor (FGF8) and FGF10 identified in patients with conotruncal defects

Journal of Translational Medicine, 2020
Background Conotruncal defects (CTDs) are a type of heterogeneous congenital heart diseases (CHDs), but little is known about their etiology. Increasing evidence has demonstrated that fibroblast growth factor (FGF) 8 and FGF10 may be involved in the ...
Kun Sun, Shuang Zhou, Qingjie Wang, Zhuo Meng, Jiayu Peng, Yue Zhou, Wenting Song, Jian Wang, Sun Chen   +8 more
doaj   +1 more source