Results 71 to 80 of about 1,606,538 (419)

Fibroblast Growth Factor 2 Augments Transforming Growth Factor Beta 1 Induced Epithelial-mesenchymal Transition in Lung Cell Culture Model

Iranian Journal of Allergy, Asthma and Immunology, 2020
Impaired lung epithelial cell regeneration following injury may contribute to the development of pulmonary fibrosis. Epithelial-mesenchymal transition (EMT) is a critical event in embryonic development, wound healing following injury, and even cancer ...
Lamis M.F. El-Baz, Nahla M. Shoukry, Hani S. Hafez, Robert D. Guzy, Mohamed Labib Salem   +4 more
doaj   +1 more source

Fibroblast mediated dynamics in diffusively uncoupled myocytes -- a simulation study using 2-cell motifs [PDF]

arXiv, 2023
In healthy hearts myocytes are typically coupled to nearest neighbours through gap junctions. Under pathological conditions such as fibrosis, or in scar tissue, or across ablation lines myocytes can uncouple from their neighbours. Electrical conduction may still occur via fibroblasts that not only couple proximal myocytes but can also couple otherwise ...
arxiv  

Simulations demonstrate a simple network to be sufficient to control branch point selection, smooth muscle and vasculature formation during lung branching morphogenesis [PDF]

G. Celli\`ere, D Menshykau and Dagmar Iber (2012) Biology Open 1, 775-788, 2012
Proper lung functioning requires not only a correct structure of the conducting airway tree, but also the simultaneous development of smooth muscles and vasculature. Lung branching morphogenesis is strongly stereotyped and involves the recursive use of only three modes of branching.
arxiv   +1 more source

Molecular cloning and expression of novel fibroblast growth factor-2 conjugated with immunodominant domains of pseudomonas exotoxin [PDF]

, 2015
Angiogenesis is very important in cancer growth and metastasis. Basic fibroblast growth factor (bFGF) as one of the most important angiogenesis factors is an attractive target for cancer vaccine.
Farazmandfar, T., Haghighatfard, H., Hakemi, M.G., Jadidi-Niaragh, F., Samaei, N.M., Yamchi, A., Yazdani, Y.   +6 more
core   +1 more source

Thrombin‐mediated impairment of fibroblast growth factor‐2 activity [PDF]

The FEBS Journal, 2009
Thrombin generation increases in several pathological conditions, including cancer, thromboembolism, diabetes and myeloproliferative syndromes. During tumor development, thrombin levels increase along with several other molecules, including cytokines and angiogenic factors.
Totta P, De Cristofaro R, GIAMPIETRI, Claudia, Aguzzi MS, Faraone D, Capogrossi MC, Facchiano A.   +6 more
openaire   +6 more sources

Combined therapy of platelet-rich plasma and basic fibroblast growth factor using gelatin-hydrogel sheet for rotator cuff healing in rat models

Journal of Orthopaedic Surgery and Research, 2021
Introduction Excellent outcomes of arthroscopic rotator cuff repair for small and medium tears have been recently reported. However, re-tears after surgery have been a common complication after surgical repair of large and massive rotator cuff tears and ...
Takeshi Kataoka, Yutaka Mifune, Atsuyuki Inui, Hanako Nishimoto, Takashi Kurosawa, Kohei Yamaura, Shintaro Mukohara, Takehiko Matsushita, Takahiro Niikura, Yasuhiko Tabata, Ryosuke Kuroda   +10 more
doaj   +1 more source

Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway [PDF]

, 2007
BACKGROUND: Prostaglandin E(2) (PGE(2)) has been shown to modulate angiogenesis and tumour progression via the E-series prostanoid-2 (EP2) receptor. Endometrial adenocarcinomas may be exposed to endogenous PGE(2) and exogenous PGE(2), present at high ...
A.R. Williams, Abramovitz, Benard, Bendvold, Billottet, Buchanan, Davidson, Ferrandina, Giavazzi, Gupta, H.N. Jabbour, Hwang, Jaaro, Jabbour, Jabbour, Jabbour, Jeremias, K.J. Sales, Kitamura, Lumsden, Luttrell, Milling, Narumiya, Pai, Pecorelli, Perchick, Pierce, Presta, R.A. Anderson, Regan, Robertson, S. Battersby, S. Gardner, Sales, Sales, Sales, Sales, Sales, Seger, Smalley, Smith, Taylor, Templeton, Tjandrawinata, Tong, Tsujii, Vane, Woodward, Yoshida   +48 more
core   +1 more source

FGFR2 (fibroblast growth factor receptor 2) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on FGFR2 (fibroblast growth factor receptor 2), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +3 more sources

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2.

Proceedings of the National Academy of Sciences of the United States of America, 1998
Basic fibroblast growth factor (FGF2) is a wide-spectrum mitogenic, angiogenic, and neurotrophic factor that is expressed at low levels in many tissues and cell types and reaches high concentrations in brain and pituitary.
S. Ortega, M. Ittmann, S. Tsang, M. Ehrlich, C. Basilico   +4 more
semanticscholar   +1 more source