Results 21 to 30 of about 536,398 (346)

Lipocalin 2 stimulates bone fibroblast growth factor 23 production in chronic kidney disease

open access: yesBone Research, 2021
Bone-produced fibroblast growth factor 23 (FGF23) increases in response to inflammation and iron deficiency and contributes to cardiovascular mortality in chronic kidney disease (CKD). Neutrophil gelatinase-associated lipocalin (NGAL or lipocalin 2; LCN2
Guillaume Courbon   +10 more
semanticscholar   +1 more source

The Measurement and Interpretation of Fibroblast Growth Factor 23 (FGF23) Concentrations

open access: yesCalcified Tissue International, 2022
Two decades after the discovery of the hormone FGF23, we know more about phosphate homeostasis as it turned out that FGF23 is the central hormone that regulates this.
A. Heijboer, E. Cavalier
semanticscholar   +1 more source

Tumor-induced osteomalacia: Easing the diagnosis with fibroblast growth factor 23

open access: yesAPIK Journal of Internal Medicine, 2022
Tumor-induced osteomalacia (TIO), is a rare paraneoplastic syndrome resulting in bone pain, muscle weakness, and recurrent fractures. Hypophosphatemia, hyperphosphaturia, low 1, 25 dihydroxyVitamin D, and normal serum calcium are noted.
Mala Dharmalingam, Lohit Kumbar
doaj   +1 more source

Effects of Single Vitamin D Injection (200,000 Units) on Serum Fibroblast Growth Factor 23 and Sclerostin Levels in Subjects with Vitamin D Deficiency [PDF]

open access: yesEndocrinology and Metabolism, 2017
BackgroundVitamin D deficiency remains common in all age groups and affects skeletal and non-skeletal health. Fibroblast growth factor 23 is a bone-derived hormone that regulates phosphate and 1,25-dihydroxyvitamin D homeostasis as a counter regulatory ...
Dongdong Zhang   +5 more
doaj   +1 more source

Hypophosphataemia, fibroblast growth factor 23 and third-generation intravenous iron compounds: a narrative review

open access: yesDrugs in Context, 2021
Third-generation intravenous (i.v.) iron preparations are safe and efficacious and are increasingly used in the treatment of iron-deficiency anaemia.
X. Kassianides, S. Bhandari
semanticscholar   +1 more source

How Fibroblast Growth Factor 23 Works [PDF]

open access: yesJournal of the American Society of Nephrology, 2007
There is a discontinuum of hereditary and acquired disorders of phosphate homeostasis that are caused by either high or low circulating levels of the novel phosphaturic hormone fibroblastic growth factor 23 (FGF23). Disorders that are caused by high circulating levels of FGF23 are characterized by hypophosphatemia, decreased production of 1,25 ...
Shiguang, Liu, L Darryl, Quarles
openaire   +2 more sources

Fibroblast Growth Factor 23 [PDF]

open access: yesJournal of the American Society of Nephrology, 2005
Although phosphate is important in skeletal mineralization, energy metabolism, and multiple enzymatic processes, little has been understood about the regulation of phosphate in health and disease until recently.
Erik A, Imel, Michael J, Econs
openaire   +2 more sources

Evocalcet with vitamin D receptor activator treatment for secondary hyperparathyroidism

open access: yesPLoS ONE, 2022
This ad hoc analysis of a previously conducted phase 3 head-to-head comparison study of evocalcet and cinacalcet in secondary hyperparathyroidism patients undergoing maintenance hemodialysis evaluated the efficacy and safety of combined once-daily oral ...
Takashi Shigematsu   +5 more
doaj   +2 more sources

Excessive fibroblast growth factor 23 promotes renal fibrosis in mice with type 2 cardiorenal syndrome

open access: yesAging, 2021
Cardiorenal syndrome (CRS) has a high mortality, but its pathogenesis remains elusive. Fibroblast growth factor 23 (FGF23) is increased in both renal dysfunction and cardiac dysfunction, and FGF receptor 4 (FGFR4) has been identified as a receptor for ...
Huixin Hao   +14 more
semanticscholar   +1 more source

Neurofibromatosis type 1 associated with hypophosphatemic osteomalacia due to hypersecretion of fibroblast growth factor 23: a case report

open access: yesJournal of Medical Case Reports, 2020
Background Neurofibromatosis type 1 is characterized by multiple café au lait spots and cutaneous and plexiform neurofibromas, and is one of the most common autosomal dominant hereditary disorders caused by mutations of the neurofibromatosis type 1 tumor
Takahiko Obo   +4 more
doaj   +1 more source

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