Results 21 to 30 of about 232,776 (304)
Journal of Medical Case Reports, 2020 Background Neurofibromatosis type 1 is characterized by multiple café au lait spots and cutaneous and plexiform neurofibromas, and is one of the most common autosomal dominant hereditary disorders caused by mutations of the neurofibromatosis type 1 tumor
Takahiko Obo +4 more
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Fibroblast Growth Factor-23 (FGF-23) e Sindrome Cardiorenale
Giornale di Clinica Nefrologia e Dialisi, 2015 non disponibile (Cardionephrology)
Luca Di Lullo +6 more
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Serum intact fibroblast growth factor 23 in healthy paediatric population
Open Medicine, 2021 It is believed that fibroblast growth factor 23 (FGF23) can become an early biomarker of chronic kidney disease progression. Data on FGF23 age dependency are inconsistent.
Stanczyk Malgorzata +3 more
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Fibroblast growth factor 23: fueling the fire [PDF]
Kidney International, 2016 In chronic kidney disease, systemic inflammation is common and associated with mortality. The present study demonstrates that fibroblast growth factor 23 (FGF23) contributes to uremic inflammation by increasing hepatic expression and secretion of inflammatory cytokines.
Hanudel, Mark +2 more
openaire +4 more sources
MicroRNA-297a regulates vascular calcification by targeting fibroblast growth factor 23 [PDF]
Iranian Journal of Basic Medical Sciences, 2016 Objective(s): Vascular calcification is one the major characteristics in patients with various types of chronic inflammatory disorders. MiRNAs have been shown to be involved in many normal biological functions as well as diseases; however, their role in ...
Shouhua Zheng +6 more
doaj +1 more source
Multiple faces of fibroblast growth factor-23 [PDF]
Current Opinion in Nephrology and Hypertension, 2016 This review examines the role of fibroblast growth factor-23 (FGF-23) in mineral metabolism, innate immunity and adverse cardiovascular outcomes.FGF-23, produced by osteocytes in bone, activates FGFR/α-Klotho (α-Kl) complexes in the kidney. The resulting bone-kidney axis coordinates renal phosphate reabsorption with bone mineralization, and creates a ...
Xiaobin, Han, L Darryl, Quarles
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Role of Fibroblast Growth Factor 23 (FGF23) and αKlotho in Cancer
Frontiers in Cell and Developmental Biology, 2021 Together with fibroblast growth factors (FGFs) 19 and 21, FGF23 is an endocrine member of the family of FGFs. Mainly secreted by bone cells, FGF23 acts as a hormone on the kidney, stimulating phosphate excretion and suppressing formation of 1,25(OH)2D3 ...
Franz Ewendt +2 more
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Frontiers in Physiology, 2020 Dietary phosphorus oversupply wastes non-renewable natural resources and raises environmental concerns in animal agriculture. We hypothesized that laying hens do not need large safety margins for dietary phosphorus because of the existence of fibroblast ...
Zhouzheng Ren +8 more
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Fibroblast-growth factor 23 promotes terminal differentiation of ATDC5 cells. [PDF]
PLoS ONE, 2017 Fibroblast Growth Factor 23 (FGF23) is well documented as a crucial player in the systemic regulation of phosphate homeostasis. Moreover, loss-of-function experiments have revealed that FGF23 also has a phosphate-independent and local impact on ...
Mathilde Guibert +3 more
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Inflammation regulates fibroblast growth factor 23 production [PDF]
Current Opinion in Nephrology and Hypertension, 2016 Fibroblast growth factor 23 (FGF23) is a hormone secreted by osteocytes and osteoblasts that regulates phosphorus and vitamin D homeostasis. FGF23 levels increase progressively in chronic kidney disease (CKD), and FGF23 excess might be a causal factor of left ventricular hypertrophy, CKD progression and death.
Connor, Francis, Valentin, David
openaire +2 more sources