Results 121 to 130 of about 8,552 (153)

The FGF23/α-Klotho Axis in Postmenopausal Osteoporosis: Associations with Bone Mineral Density and Diagnostic Discrimination. [PDF]

J Clin Med
Karalok MH, Misirlioglu NF, Akin OD, Uzun H.   +3 more
europepmc   +1 more source

Phosphate: An Anion Controlling Metabolic Functions. [PDF]

Nutrients
Tarantino U, Greggi C, Gasperini B, Scimeca M, Iundusi R, Gasbarra E, Brandi ML.   +6 more
europepmc   +1 more source

Klotho revisited: tubular heterogeneity reshapes mineral metabolism, aging, and CKD. [PDF]

Pflugers Arch
Pathare G.
europepmc   +1 more source

Fibroblast Growth Factor 23 (FGF23) and Klotho Protein in Beta-Thalassemia

Hormone and Metabolic Research, 2020
AbstractDerangements in phosphate and calcium homeostasis are common in patients with beta-thalassemia. Fibroblast growth factor 23 (FGF23) is among the main hormones regulating phosphate levels, while several studies underline an interplay between iron (Fe) and FGF23.
Athanasios G Papavassiliou, Antonis Galanos   +1 more
exaly   +4 more sources

Serum Fibroblast Growth Factor 23 (FGF23) in Patients with Rheumatoid Arthritis

Internal Medicine, 2016
Objective Rheumatoid arthritis (RA) is a chronic inflammatory disease accompanied by periarticular and systemic osteoporosis. Fibroblast growth factor 23 (FGF23), which is mainly produced by osteocytes, circulates to the kidneys and regulates bone metabolism.
Ichiei Narita, Hiroe Sato, Asami Abe
exaly   +4 more sources

Erythropoietin stimulates fibroblast growth factor 23 (FGF23) in mice and men [PDF]

Pflugers Archiv European Journal of Physiology, 2018
Fibroblast growth factor 23 (FGF23) is a major endocrine regulator of phosphate and 1,25 (OH)2 vitamin D3 metabolism and is mainly produced by osteocytes. Its production is upregulated by a variety of factors including 1,25 (OH)2 vitamin D3, high dietary phosphate intake, and parathyroid hormone (PTH).
Roland H Wenger, Pedro H Imenez Silva, Carsten A. Wagner   +2 more
exaly   +4 more sources

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Vitamin A regulates fibroblast growth factor 23 (FGF23)

Nutrition, 2020
Renal phosphate and vitamin D metabolism are regulated by proteohormone fibroblast growth factor 23 (FGF23), which is secreted by bone cells. FGF23 inhibits phosphate reabsorption and the production of calcitriol, active vitamin D (1,25(OH)2D3). FGF23 generated by other cells exerts further paracrine effects in the liver, heart, and immune system.
Steffen Rausch, Michelle Barholz, Michael Föller, Martina Feger   +3 more
openaire   +2 more sources

Fibroblast Growth Factor 23 (FGF23) and the kidney

The International Journal of Artificial Organs, 2009
Phosphate homeostasis in humans is a complex phenomenon involving the interplay of several different organs and circulating hormones. Among the latter, parathyroid hormone (PTH), and vitamin D 3 (Vit D 3 ) were thought to be the main regulators of serum
George, Tsagalis, Erasmia, Psimenou, Efstathios, Manios, Antonios, Laggouranis   +3 more
openaire   +2 more sources

Fibroblast growth factor 23 (FGF23) and mortality: The Ludwigshafen Risk and Cardiovascular Health Study

Atherosclerosis, 2014
Fibroblast growth factor 23 (FGF23) is an important regulatory hormone in phosphate and vitamin D metabolism. Here, we investigated the associations of FGF23 with traditional cardiovascular risk factors and with bone metabolism parameters as well as the impact of FGF23 upon long-term mortality in a large cohort of patients referred for coronary ...
Nikolaus Marx, Tatjana Stojakovic, Stefan Pilz   +2 more
exaly   +4 more sources

Calcineurin inhibitors regulate fibroblast growth factor 23 (FGF23) synthesis

Naunyn-Schmiedeberg's Archives of Pharmacology, 2017
Fibroblast growth factor 23 (FGF23) inhibits renal phosphate reabsorption and calcitriol formation, effects depending on Klotho as a co-receptor for FGF23. In addition, FGF23/Klotho strongly influences aging and the onset of age-associated diseases. The synthesis of FGF23 by bone cells is induced by store-operated Ca2+ entry (SOCE) through Orai1 in ...
Ludmilla Bär, Claudia Großmann, Michael Gekle, Michael Föller   +3 more
openaire   +2 more sources