Results 101 to 110 of about 74,102 (246)

Regulatory effect of FGF2 on the expression of R-spondin 1 in mouse intestinal stromal cells

Shanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To preliminarily investigate the regulatory effect and underlying mechanism of fibroblast growth factor 2 (FGF2) on R-spondin 1 (Rspo1) expression in CD34+CD81+ stromal cells from the mouse colon.Methods·Colonic CD45-CD326-CD31-GP38+CD81+Rspo1 ...
LI Jingcong, ZHAO Han, LIN Qiaowen, SUN Hongxiang, SU Bing, WU Ningbo   +5 more
doaj   +1 more source

Inhibitive Effects of FGF2/FGFR1 Pathway on Astrocyte-Mediated Inflammation in vivo and in vitro After Infrasound Exposure

Frontiers in Neuroscience, 2018
Infrasound, a kind of ambient noise, can cause severe disorders to various human organs, specially to central nervous system (CNS). Our previous studies have shown that infrasound-induced CNS injury was closely related with astrocytes activation and ...
Ya-Jun Shi, Ya-Jun Shi, Ming Shi, Li-Jun Xiao, Li Li, Lin-Hui Zou, Chao-Yang Li, Qin-Jun Zhang, Lin-Fu Zhou, Xin-Chao Ji, Huan Huang, Ye Xi, Ling Liu, Hong-Ya Zhang, Gang Zhao, Lei Ma   +15 more
doaj   +1 more source

Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival [PDF]

, 2006
There are two types of neural stem cells (NSCs). Primitive NSCs [leukemia inhibitory factor (LIF) dependent but exogenous fibroblast growth factor (FGF) 2 independent] can be derived from mouse embryonic stem (ES) cells in vitro and from embryonic day 5 ...
Chaddah, R, Ema, M, Haigh, Jody, Hitoshi, S, Nagy, A, Rossant, J, van der Kooy, D, Wada, T   +7 more
core   +3 more sources

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

Developmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore, Anjali Balakrishnan, Yacine Touahri, Dawn Zinyk, Humna Noman, Satoshi Okawa, Jeff Biernaskie, Carol Schuurmans   +7 more
wiley   +1 more source

Microarray analysis of cultured human brain aggregates following cortisol exposure: Implications for cellular functions relevant to mood disorders

Neurobiology of Disease, 2006
Increased cortisol levels in humans are often observed in patients suffering from mood disorders. In this study human fetal brain aggregates were exposed to cortisol at 500 nM for 3 weeks, as an in-vitro model of chronic cortisol exposure.
S. Salaria, G. Chana, F. Caldara, E. Feltrin, M. Altieri, F. Faggioni, E. Domenici, E. Merlo-Pich, I.P. Everall   +8 more
doaj   +1 more source

FGF2 Stimulates COUP-TFII Expression via the MEK1/2 Pathway to Inhibit Osteoblast Differentiation in C3H10T1/2 Cells. [PDF]

PLoS ONE, 2016
Chicken ovalbumin upstream promoter transcription factor II (COUP-TFII) is an orphan nuclear receptor that regulates many key biological processes, including organ development and cell fate determination.
Mi Nam Lee, Jung-Woo Kim, Sin-Hye Oh, Byung-Chul Jeong, Yun-Chan Hwang, Jeong-Tae Koh   +5 more
doaj   +1 more source

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

ChitoSilkBioPatch: A bio‐inspired wound dressing scaffold for antibiotic‐free diabetic wound management

VIEW, EarlyView.
We present ChitoSilkBioPatch, a maleimide‐functionalized chitosan/dACM hydrogel integrated with a stretchable nanopatterned silk mesh to provide intrinsic, antibiotic‐free antibacterial activity and bioactive wound support. The scaffold eliminates S. aureus and P.
Dorsa Dehghan‐Baniani, Babak Mehrjou, Yucong Li, Zhaowei Jiang, Xiaomin Lu, Yin Xiao, Huanxiong Chen, Tsz Lam Yiu, Chi Chiu Wang, Hongkai Wu, Gang Li, Paul K. Chu, Wayne Yuk Wai Lee   +12 more
wiley   +1 more source

Engineered autocrine signaling eliminates muscle cell FGF2 requirements for cultured meat production

Cell Reports Sustainability
Summary: Cultivated meat (also known as cultured meat) is a promising technology that faces substantial cost barriers, which are currently driven by the price of media components.
Andrew J. Stout, Xiaoli Zhang, Sophia M. Letcher, Miriam L. Rittenberg, Michelle Shub, Kristin M. Chai, Maya Kaul, David L. Kaplan   +7 more
doaj   +1 more source