Results 121 to 130 of about 74,102 (246)

Ideal soft tissue graft in periodontal and peri‐implant applications: A scoping review

Periodontology 2000, EarlyView.
Abstract Soft tissue grafts (STG) are used in a wide range of clinical situations including volume augmentation, keratinized tissue increase, and recession coverage around teeth and implants. Each STG, produced from different sources and processed with various techniques, possesses unique material properties and interaction with the host tissues, which
Madeline Yon, Elena Calciolari, Nikos Mardas, Anton Sculean, Nikolaos Donos   +4 more
wiley   +1 more source

Nuclear localization of mouse fibroblast growth factor 2 requires N-terminal and C-terminal sequences [PDF]

, 2018
In vertebrates, different isoforms of fibroblast growth factor 2 (FGF2) exist, which differ by their N-terminal extension. They show different localization and expression levels and exert distinct biological effects. Nevertheless, genetic inactivation of
Beermann, F., Foletti, A., Vuadens, F.
core  

Treating age‐related loss of muscle mass and function: Where should we be focusing?

The Journal of Physiology, EarlyView.
Abstract figure legend Perturbations contributing to the age‐related loss of muscle mass and strength. A, in the spinal cord, self‐reinforcing cycles of oxidative stress, mitochondrial dysfunction and inflammation mediated by cells, including microglia, contribute to motor neuron degeneration.
Daniel J. Ham, Christopher S. Fry, Avnika Ashok Ruparelia, Shyuan T. Ngo, Séverine Lamon   +4 more
wiley   +1 more source

Matrigel plug assay: evaluation of the angiogenic response by reverse transcription-quantitative PCR [PDF]

, 2013
The subcutaneous Matrigel plug assay in mice is a method of choice for the in vivo evaluation of pro- and anti-angiogenic molecules. However, quantification of the angiogenic response in the plug remains a problematic task.
Belleri M., Coltrini D., Di Salle E., Presta M., Ronca R., Testini C.   +5 more
core   +1 more source

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman, Mossammat Rima Akter, Nur Alam   +2 more
wiley   +1 more source

Functional Differences between GDNF-Dependent and FGF2-Dependent Mouse Spermatogonial Stem Cell Self-Renewal

Stem Cell Reports, 2015
Spermatogonial stem cells (SSCs) are required for spermatogenesis. Earlier studies showed that glial cell line-derived neurotrophic factor (GDNF) was indispensable for SSC self-renewal by binding to the GFRA1/RET receptor.
Seiji Takashima, Mito Kanatsu-Shinohara, Takashi Tanaka, Hiroko Morimoto, Kimiko Inoue, Narumi Ogonuki, Mayumi Jijiwa, Masahide Takahashi, Atsuo Ogura, Takashi Shinohara   +9 more
doaj   +1 more source

Decrease in excitatory neurons, astrocytes and proliferating progenitors in the cerebral cortex of mice lacking exon 3 from the Fgf2 gene [PDF]

, 2008
BACKGROUND:The Fgf2 gene is expressed in the brain neuroepithelium during embryonic development and in astroglial cells throughout life. Previous knockout studies suggested that FGF2 plays a role in the proliferation of neural progenitors in the ...
Dana Shin, Flora M Vaccarino, Hongqi Li, Kesi Chen, L. Philip Sanford, Thomas Doetschman, Yasushi Ohkubo   +6 more
core   +2 more sources

Astrocytes as central integrators of neural circuit function: Mechanisms and dysregulation in neuropsychiatric disorders

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
1. Astrocytes are central integrators of neural circuit function through tripartite synapse modulation and neurovascular coupling. 2. Dysregulation of glutamate/GABA homeostasis and neuroinflammation represents shared mechanisms across diverse neuropsychiatric disorders. 3.
Xinyu Liu, Xinyue Zhou, Ruotong Meng, Yanxi Chen, You Chen, Blake Highet, Maurice Curtis, Bernhard Hirt, Shunying Yu, Jin Zhou, Linya You   +10 more
wiley   +1 more source

Fibroblast growth factor signaling in skeletal development and disease [PDF]

, 2015
Fibroblast growth factor (FGF) signaling pathways are essential regulators of vertebrate skeletal development. FGF signaling regulates development of the limb bud and formation of the mesenchymal condensation and has key roles in regulating ...
Marie, Pierre J, Ornitz, David M
core   +2 more sources

Blood Serum From Obese Women Raises ROS Production by Neural Stem Cells

Developmental Neurobiology, Volume 86, Issue 2, April 2026.
ABSTRACT Maternal obesity has been associated with adverse pregnancy outcomes and altered fetal development, but the direct influence of circulating maternal factors on early human neural cells remains poorly understood. Neural stem cells (NSCs) provide a controlled system to examine how metabolic and inflammatory changes may affect early ...
Phelipe Elias da Silva, Natássia Caroline Resende Corrêa, Natália Ferreira Silva, Carlos Ueira‐Vieira, Hebreia Oliveira Almeida‐Souza, Mario Machado Martins, Tiara da Costa Silva, Renata Graciele Zanon   +7 more
wiley   +1 more source