Results 211 to 220 of about 74,102 (246)

Engineering Fibroblast Growth Factor-2 (FGF2) Production in Cyanobacteria. [PDF]

open access: possibleACS Synthetic Biology
The Fibroblast Growth Factor 2 (FGF2) is an important signaling protein that serves to activate a variety of biological processes in animal and human cells. The FGF2 comprises an uncommon β-barrel structure composed of β-pleated sheets and loops only. It
B. K. Majhi, A. Melis
semanticscholar   +2 more sources
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Systemic administration of fibroblast growth factor-2 (FGF2) reduces BACE1 expression and amyloid pathology in APP23 mice.

Neurobiology of Aging, 2015
There is an emerging evidence that growth factors may have a potential beneficial use in the treatment of Alzheimer's disease (AD) because of their neuroprotective properties and effects on neuronal proliferation. Basic fibroblast growth factor or fibroblast growth factor-2 (FGF2) is an anti-inflammatory, angiogenic, and neurotrophic factor that is ...
Loukia Katsouri   +5 more
semanticscholar   +4 more sources

Fibroblast growth factor 2 (FGF2) and vascular endothelial growth factor A (VEGFA) synergistically promote steroidogenesis and survival of cultured buffalo granulosa cells.

Animal Reproduction Science, 2017
The present study investigated the combined effect of fibroblast growth factor 2 (FGF2) and vascular endothelial growth factor A (VEGF-A) on estradiol (E2) secretion and relative abundance of mRNA for aromatase enzyme (CYP19A1), proliferating cell nuclear antigen (PCNA) and BCL-2 associated X protein (BAX) in cultured buffalo granulosa cells (GCs ...
S. R. Mishra   +8 more
semanticscholar   +3 more sources

Site-specific conjugation of fibroblast growth factor 2 (FGF2) based on incorporation of alkyne-reactive unnatural amino acid.

Bioorganic & Medicinal Chemistry, 2017
Recent advances in site-specific protein modification include the increasingly popular incorporation of unnatural amino acid(s) using amber codon, a method developed by Schultz and coworkers. In this study, we employ this technique to introduce propargyllysine (PrK) in human fibroblast growth factor 2 (FGF2). Owing to an alkyne moiety in its side chain,
K. Swiderska   +4 more
semanticscholar   +3 more sources

Analysis of fibroblast growth factor 2 (FGF2) gene transcription and protein distribution in the bovine testis

Growth Factors, 2005
Several fibroblast growth factors (FGFs) are implicated in proliferation and differentiation of both somatic and germ cells during testicular development, as well as in spermatogenesis of adult testis. The expression of FGF2 was studied in the adult bovine testis using quantitative RT-PCR, RNA in situ hybridization, and immunohistochemistry ...
A. Abd-Elmaksoud   +4 more
semanticscholar   +3 more sources

Fibroblast growth factor 2.

Differentiation; research in biological diversity, 2023
Fibroblast Growth Factor 2 (FGF2), also known as basic fibroblast growth factor, is a potent stimulator of growth and differentiation in multiple tissues.
Audrey Nickle   +2 more
semanticscholar   +1 more source

ASSOCIATION OF FIBROBLAST GROWTH FACTOR 2 (FGF2) WITH HIPPOCAMPAL VOLUME IN DUTCH SCHIZOPHRENIA PATIENTS

Schizophrenia Research, 2008
s / Schizophrenia Research 102/1–3, Supplement 2 (2008) 1–279 17 Methods: Forty-four patients with first-episode schizophrenia, 50 patients with first-episode affective psychosis, and 50 ageand gender- matched controls were evaluated using MRI. Based on a previous study by Chiavaras and Petrides, the orbitofrontal sulcogyral pattern was visually ...
Steven Bakker   +7 more
openaire   +1 more source

Affibody-mediated controlled release of fibroblast growth factor 2.

Journal of Controlled Release, 2022
Protein therapeutics possess high target affinity and specificity, yet short residence times, which limit their broad utility. To overcome this challenge, we used affinity interactions to modulate protein release from a hydrogel delivery vehicle thereby ...
Chiara Bostock   +5 more
semanticscholar   +1 more source

Cyclic and dimeric fibroblast growth factor 2 variants with high biomedical potential.

International Journal of Biological Macromolecules, 2022
Fibroblast growth factor 2 (FGF2) is a pleiotropic protein engaged in the regulation of key cellular processes in a wide spectrum of cells. FGF2 is an important object of basic research as well as a molecule used in regenerative medicine, in vitro cell ...
M. Krzyścik   +3 more
semanticscholar   +1 more source

Fibroblast growth factor-2, derived from cancer-associated fibroblasts, stimulates growth and progression of human breast cancer cells via FGFR1 signaling.

Molecular Carcinogenesis, 2020
Cancer-associated fibroblasts (CAFs) constitute a major compartment of the tumor microenvironment. In the present study, we investigated the role for CAFs in breast cancer progression and underlying molecular mechanisms.
Jinyoung Suh   +4 more
semanticscholar   +1 more source

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