The FASEB Journal, 2016 Cardiovascular disease is the leading cause of death in men and women; in particular, coronary artery disease or ischemic heart disease, leading to myocardial infarction (MI), affects 1.9 million Americans yearly and makes up more than half of all ...
R. Harris +8 more
semanticscholar +2 more sources
Toward FGF2 reduction in cultured meat media: polyphenol salts enhance growth and differentiation of bESC aggregates [PDF]
Frontiers in NutritionRecombinant growth factors, particularly fibroblast growth factor 2 (FGF2), are major cost drivers in the production of cultured meat. In this study, we investigated the potential of polyphenol salts to reduce reliance on FGF2 in media supporting the ...
Gaya Savyon +12 more
doaj +2 more sources
Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts [PDF]
, 2013 The incidence of craniosynostosis is one in every 1,800-2500 births. The gene-environment model proposes that if a genetic predisposition is coupled with environmental exposures, the effects can be multiplicative resulting in severely abnormal phenotypes.
A Mansukhani +58 more
core +18 more sources
Scientific Reports, 2021 Growth factor-eluting polymer systems have been widely reported to improve cell and tissue outcomes; however, measurements of actual growth factor concentration in cell culture conditions are limited.
Ivan Ding, Amy M. Peterson
doaj +1 more source
FGF2 (fibroblast growth factor 2 (basic)) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on FGF2 (fibroblast growth factor 2 (basic)), with data on DNA, on the protein encoded, and where the gene is implicated.
MacFarlane, LA, Murphy, P
openaire +2 more sources
Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway [PDF]
, 2007 BACKGROUND: Prostaglandin E(2) (PGE(2)) has been shown to modulate angiogenesis and tumour progression via the E-series prostanoid-2 (EP2) receptor. Endometrial adenocarcinomas may be exposed to endogenous PGE(2) and exogenous PGE(2), present at high ...
A.R. Williams +48 more
core +5 more sources
npj Precision Oncology, 2023 Cancer cell resistance arises when tyrosine kinase inhibitor (TKI)-targeted therapies induce a drug-tolerant persister (DTP) state with growth via genetic aberrations, making DTP cells potential therapeutic targets.
Koh Furugaki +6 more
doaj +1 more source
Enhancing the Efficacy of Stem Cell Therapy with Glycosaminoglycans
Stem Cell Reports, 2020 Summary: Human mesenchymal stem cell (hMSC) therapy offers significant potential for osteochondral regeneration. Such applications require their ex vivo expansion in media frequently supplemented with fibroblast growth factor 2 (FGF2). Particular heparan
Ling Ling +14 more
doaj +1 more source
Multiple Therapeutic Applications of RBM-007, an Anti-FGF2 Aptamer
Cells, 2021 Vascular endothelial growth factor (VEGF) plays a pivotal role in angiogenesis, but is not the only player with an angiogenic function. Fibroblast growth factor-2 (FGF2), which was discovered before VEGF, is also an angiogenic growth factor.
Yoshikazu Nakamura
doaj +1 more source
The Use of Human Serum Samples to Study Malignant Transformation: A Pilot Study
Cells, 2021 Obesity and excess adiposity account for approximately 20% of all cancer cases; however, biomarkers of risk remain to be elucidated. While fibroblast growth factor-2 (FGF2) is emerging as an attractive candidate biomarker for visceral adipose tissue mass,
Andreana N. Holowatyj +7 more
doaj +1 more source