Results 11 to 20 of about 356,203 (328)

Fibroblast growth factor receptor 3 alterations and response to immune checkpoint inhibition in metastatic urothelial cancer: a real world experience. [PDF]

Br J Cancer, 2021
Rose TL, Weir WH, Mayhew GM, Shibata Y, Eulitt P, Uronis JM, Zhou M, Nielsen M, Smith AB, Woods M, Hayward MC, Salazar AH, Milowsky MI, Wobker SE, McGinty K, Millburn MV, Eisner JR, Kim WY.   +17 more
europepmc   +3 more sources

Large, Nested Variant of Urothelial Carcinoma Is Enriched with Activating Mutations in Fibroblast Growth Factor Receptor-3 among Other Targetable Mutations. [PDF]

Cancers (Basel), 2023
Gamallat Y, Afsharpad M, El Hallani S, Maher CA, Alimohamed N, Hyndman E, Bismar TA.   +6 more
europepmc   +3 more sources

Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody

Disease Models & Mechanisms, 2016
Activating mutations in fibroblast growth factor receptor 3 (FGFR3) have been identified in multiple types of human cancer and in congenital birth defects.
Yongjun Yin, Xiaodi Ren, Craig Smith, Qianxu Guo, Maria Malabunga, Ilhem Guernah, Yiwei Zhang, Juqun Shen, Haijun Sun, Nabil Chehab, Nick Loizos, Dale L. Ludwig, David M. Ornitz   +12 more
doaj   +2 more sources

Co-expression of fibroblast growth factor receptor 3 with mutant p53, and its association with worse outcome in oropharyngeal squamous cell carcinoma. [PDF]

PLoS One, 2021
Nannapaneni S, Griffith CC, Magliocca KR, Chen W, Lyu X, Chen Z, Wang D, Wang X, Shin DM, Chen ZG, Saba NF.   +10 more
europepmc   +3 more sources

Fibroblast Growth Factor Receptor 3 Alteration Status is Associated with Differential Sensitivity to Platinum-based Chemotherapy in Locally Advanced and Metastatic Urothelial Carcinoma. [PDF]

Eur Urol, 2020
Teo MY, Mota JM, Whiting KA, Li HA, Funt SA, Lee CH, Solit DB, Al-Ahmadie H, Milowsky MI, Balar AV, Pietzak E, Dalbagni G, Bochner BH, Ostrovnaya I, Bajorin DF, Rosenberg JE, Iyer G.   +16 more
europepmc   +3 more sources

In situ imaging of quantum dot-AZD4547 conjugates for tracking the dynamic behavior of fibroblast growth factor receptor 3 [PDF]

International Journal of Nanomedicine, 2017
Gyoyeon Hwang,1,2,* Hyeonhye Kim,1,* Hojong Yoon,1 Chiman Song,1 Dong-Kwon Lim,3 Taebo Sim,1,3 Jiyeon Lee1,2 1Chemical Kinomics Research Center, Materials and Life Science Research Division, Korea Institute of Science and Technology, Seoul, 2Bio-Med ...
Hwang G, Kim H, Yoon H, Song C, Lim D, Sim T, Lee J   +6 more
doaj   +2 more sources

Fibroblast growth factor receptor 3-IIIc mediates colorectal cancer growth and migration [PDF]

British Journal of Cancer, 2010
Deregulation of fibroblast growth factor receptor 3 (FGFR3) is involved in several malignancies. Its role in colorectal cancer has not been assessed before.Expression of FGFR3 in human colorectal tumour specimens was analysed using splice variant-specific real-time reverse transcriptase PCR assays.
Gudrun Sonvilla, Sigrid Allerstorfer, Christine Heinzle, Stefan Stättner, J. Karner, M. Klimpfinger, Friedrich Wrba, Hendrik Fischer, Christine Gauglhofer, Sabine Spiegl‐Kreinecker, Bettina Grasl‐Kraupp, Klaus Holzmann, Michael Grusch, Walter Berger, Brigitte Marian   +14 more
openalex   +3 more sources

Activation of the Fibroblast Growth Factor Receptor 3 in Bladder Cancer [PDF]

, 2007
The identification of frequent FGFR3 mutations in superficial bladder cancer suggests that mutation of the FGFR3 gene is a key genetic event in the development of noninvasive bladder tumors. Furthermore, FGFR3 mutations were associated with a good
Oers, J.M.M. (Johanna) van
core   +3 more sources

Evocalcet with vitamin D receptor activator treatment for secondary hyperparathyroidism.

PLoS ONE, 2022
This ad hoc analysis of a previously conducted phase 3 head-to-head comparison study of evocalcet and cinacalcet in secondary hyperparathyroidism patients undergoing maintenance hemodialysis evaluated the efficacy and safety of combined once-daily oral ...
Takashi Shigematsu, Shinji Asada, Yuichi Endo, Takehisa Kawata, Masafumi Fukagawa, Tadao Akizawa   +5 more
doaj   +2 more sources

Novel Fibroblast Growth Factor Receptor 3-Fatty Acid Synthase Gene Fusion in Recurrent Epithelioid Glioblastoma Linked to Aggressive Clinical Progression. [PDF]

Curr Oncol
Diaz MA, Vázquez-Gómez F, Garrido I, Arias F, Suarez J, Buño I, Lassaletta Á.   +6 more
europepmc   +3 more sources