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Modulation of Chemokine Activity for Enhanced Angiogenesis and Tissue Regeneration in Chronic Wounds. [PDF]

Int J Mol Sci
Adit GN, Srikanth K, Harithpriya K, Ganesan K, Ramkumar KM.   +4 more
europepmc   +1 more source

Spatiotemporal dynamics of mammalian wound healing. [PDF]

Cell Discov
Agramunt J, Kang Y, Rinkevich Y.
europepmc   +1 more source

Fibroblast growth factor receptors and skeletogenesis

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Cellular signaling by fibroblast growth factor receptors.

Cytokine & Growth Factor Reviews, 2005
The 22 members of the fibroblast growth factor (FGF) family of growth factors mediate their cellular responses by binding to and activating the different isoforms encoded by the four receptor tyrosine kinases (RTKs) designated FGFR1, FGFR2, FGFR3 and FGFR4.
V. P. Eswarakumar, I. Lax, J. Schlessinger   +2 more
semanticscholar   +3 more sources

Promiscuity of fibroblast growth factor receptors

BioEssays, 1996
AbstractFibroblast growth factor receptors (FGFRs) have been implicated in many developmental and regenerative events, including axial organisation, mesodermal patterning, keratinocyte organisation and brain development. The consensus view that this reflects a role for one or other of the nine known members of the fibroblast growth factor family in ...
P. Green, F. Walsh, P. Doherty
semanticscholar   +3 more sources

Basic fibroblast growth factor and fibroblast growth factor receptors in adult olfactory epithelium.

Brain Research, 2001
Basic fibroblast growth factor (FGF2) stimulates proliferation of the globose basal cells, the neuronal precursor in the olfactory epithelium. The present study investigates the expression of basic fibroblast growth factor and fibroblast growth factor receptors in the adult olfactory epithelium.
Pi-en Hsu, Fu Yu, F. Féron, J. Pickles, Kyra J. Sneesby, A. Mackay-Sim   +5 more
semanticscholar   +5 more sources

Receptors for fibroblast growth factors

Immunology & Cell Biology, 1995
SummaryThe recent discovery of the involvement of heparan sulfate proteoglycans (HSPG) in the activation of fibroblast growth factor receptors (FGFR) has led to an intensification of study of this field. It appears that the HSPG act as low affinity receptors to which the fibroblast growth factors (FGF) must bind in order to successfully activate the ...
J C, Coutts, J T, Gallagher
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Fibroblast Growth Factor Receptor Inhibitors

Current Pharmaceutical Design, 2012
Fibroblast growth factor receptors (FGFRs) play an important role in embryonic development, angiogenesis, wound healing, cell proliferation and differentiation. The fibroblast growth factor receptor (FGFR) isoforms have been under intense scrutiny for effective anticancer drug candidates.
Suneel B V S, Kumar, Lakshmi, Narasu, Rambabu, Gundla, Raveendra, Dayam, Sarma, J A R P   +4 more
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Fibroblast Growth Factors, Fibroblast Growth Factor Receptors, Diseases, and Drugs

Recent Patents on Cardiovascular Drug Discovery, 2006
Maintenance of endothelial cells (ECs), the building blocks of the vascular tree, is a presumed function of fibroblast growth factors (FGFs). In particular, the two prototypic members of FGF family, namely FGF1 and FGF2, due to their potent mitogenic and pro-migratory activities, have the ability to induce metabolic and phenotypic changes in ECs that ...
Gregory J, Chen, Reza, Forough
openaire   +2 more sources