Down-regulation of FGF10 in hypospadias prepuce associated with severity
Background: Fibroblast growth factors (FGF) expressed in the genital tubercle, especially FGF8 and FGF10, may be implicated in the morphogenesis of external genitalia. We investigated the expression of FGF8 and FGF10 in hypospadias prepuce to confirm any
Susumu Yamada+8 more
doaj
Platelet-derived-growth-factor-stimulated heterogeneous polyphosphoinositide metabolism and phosphate uptake in C3H fibroblasts [PDF]
Holm Holmsen+4 more
openalex +1 more source
Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee+10 more
wiley +1 more source
Impaired Synergism between Somatomedin C/Insulin-Like Growth Factor I and Dexamethasone in the Growth of Fibroblasts from a Patient with Insulin Resistance [PDF]
Cheryl A. Conover+2 more
openalex +1 more source
Biomimetic glycosaminoglycan analog hydrogels exhibit suitable and robust mechanical properties, as well as hemocompatibility and biocompatibility, making them ideal for the embolization of intracranial aneurysms. Notably, the hydrogel's environment‐selective swelling properties enable complete blockage of the aneurysm cavity while preventing ...
Sarit S. Sivan+8 more
wiley +1 more source
Fibroblast growth factors in control of lipid metabolism: from biological function to clinical application. [PDF]
Struik D, Dommerholt MB, Jonker JW.
europepmc +1 more source
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto+2 more
wiley +1 more source
Reduced growth-factor requirement of keloid-derived fibroblasts may account for tumor growth.
Shirley B. Russell+4 more
openalex +1 more source
SOMATOMEDIN-C (Sm-C/IGF-1) SYNERGISES WITH FIBROBLAST GROWTH FACTOR (FGF) ON SERTOLI CELLS (SC) MULTIPLICATION AND DIFFERENTIATION [PDF]
P Chatelain+3 more
openalex +1 more source