Untensed fibronectin fibers: a novel hallmark of microthrombi [PDF]
BackgroundMyocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) accounts for up to 15% of acute Myocardial Infarction (MI) cases and presents significant diagnostic and therapeutic challenges.
Arnaud Miéville+6 more
doaj +2 more sources
Adsorption of fibronectin derived from serum and from human endothelial cells onto tissue culture polystyrene [PDF]
Human endothelial cells (HEC) suspended in a culture medium containing 20% human serum (CMS) adhere and spread on(to) moderately wettable polymers, such as tissue culture polystyrene (TCPS).
Aken, W.G. van+7 more
core +21 more sources
Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin [PDF]
Functional cross-talk between Tie2 and Integrin signaling pathways is essential to coordinate endothelial cell adhesion and migration in response to the extracellular matrix, yet the mechanisms behind this phenomenon are unclear.
Barton, William A.+3 more
core +18 more sources
Regional fibronectin and collagen fibril co-assembly directs cell proliferation and microtissue morphology. [PDF]
The extracellular matrix protein, fibronectin stimulates cells to self-assemble into three-dimensional multicellular structures by a mechanism that requires the cell-dependent conversion of soluble fibronectin molecules into insoluble fibrils ...
Carlos A Sevilla+2 more
doaj +1 more source
Plasma Fibronectin as a Novel Predictor of Coronary Heart Disease: A Retrospective Study
Although fibronectin has been associated with the pathogenesis of atherosclerosis, little is currently known about the relationship between plasma fibronectin and coronary heart disease (CHD).
Longyun Peng+4 more
doaj +1 more source
The mechanisms contributing to excessive fibronectin in preeclampsia, a pregnancy-related disorder, remain unknown. Herein, we investigated the role of JMJD6, an O2- and Fe2+-dependent enzyme, in mediating placental fibronectin processing and function ...
Sruthi Alahari+18 more
doaj +1 more source
Full-Length Fibronectin Drives Fibroblast Accumulation at the Surface of Collagen Microtissues during Cell-Induced Tissue Morphogenesis. [PDF]
Generating and maintaining gradients of cell density and extracellular matrix (ECM) components is a prerequisite for the development of functionality of healthy tissue. Therefore, gaining insights into the drivers of spatial organization of cells and the
Jasper Foolen+5 more
doaj +1 more source
Fibronectin Deposition Participates in Extracellular Matrix Assembly and Vascular Morphogenesis. [PDF]
The extracellular matrix (ECM) has been demonstrated to facilitate angiogenesis. In particular, fibronectin has been documented to activate endothelial cells, resulting in their transition from a quiescent state to an active state in which the cells ...
Abigail Hielscher+4 more
doaj +1 more source
Fibronectin is an abundant and ubiquitous extracellular matrix component that regulates a wide range of cell functions by directly interacting with cell surface integrin receptors.
Khon Huynh
doaj +1 more source
Fibronectin: structure, functions, clinical significance (review)
Plasma fibronectin is a high molecular weight adhesive glycoprotein. There are two types of fibronectin: plasma (soluble) and cellular derived (insoluble).
S. A. Vasiliev+9 more
doaj +1 more source