Studies of extracellular fibronectin matrix formation with fluoresceinated fibronectin and fibronectin fragments [PDF]
Fluorescein isothiocyanate conjugated human plasma fibronectin, 70‐kDa collagen‐binding, 60‐kDa central, 60‐kDa heparin‐binding, 180‐kDa heparin, collagen‐binding fibronectin fragments and gelatin were used to study extracellular fibronectin matrix formation.
Chernousov, M.A. +2 more
openaire +3 more sources
Structural and functional studies of intrinsically disordered fibronectin-binding proteins [PDF]
Bacterial fibronectin-binding proteins (FnBPs) mediate adhesion of bacteria to host tissues through binding to the human protein fibronectin (Fn). FnBPs are predicted to contain a series of intrinsically disordered Fn-binding repeats (FnBRs), which ...
Norris, Nicole Catherine
core +6 more sources
Fibronectin protects from excessive liver fibrosis by modulating the availability of and responsiveness of stellate cells to active TGF-β. [PDF]
Fibrotic tissue in the liver is mainly composed of collagen. Fibronectin, which is also present in fibrotic matrices, is required for collagen matrix assembly in vitro. It also modulates the amount of growth factors and their release from the matrix.
Nina Kawelke +5 more
doaj +1 more source
Cells regulate adhesion to the fibrillar extracellular matrix (ECM) of which fibronectin is an essential component. However, most studies characterize cell adhesion to globular fibronectin substrates at time scales long after cells polarize and migrate ...
Seungkuk Ahn +4 more
doaj +1 more source
Candida albicans Adhesion Measured by Optical Nanomotion Detection
Cellular adhesion plays an important role in numerous fundamental physiological and pathological processes. Its measurement is relatively complex, requires sophisticated equipment, and, in most cases, cannot be carried out without breaking the links ...
Maria I. Villalba +5 more
doaj +1 more source
Outer Membrane Protein YadA of Enteropathogenic Yersiniae Mediates Specific Binding to Cellular but Not Plasma Fibronectin [PDF]
The binding of bacteria or bacterial products to host proteins of tissue extracellular matrix may be a mechanism of tissue adherence. We investigated interactions of the plasmid-encoded outer membrane protein YadA, which confers pathogenic functions on ...
Emmerich, F. +7 more
core +1 more source
Fibronectin glomerulopathy [PDF]
Fibronectin glomerulopathy occurs between the second and fifth decades of life in most patients, and it is known to be slowly progressive with mild proteinuria leading to kidney failure. The case of a 78-year-old woman with a rapid course of nephrotic syndrome due to fibronectin glomerulopathy is reported.
Ishimoto, Ikue +5 more
openaire +2 more sources
Fibronectin in human gallbladder bile: cholesterol pronucleating and/or mucin "link" protein? [PDF]
Some biliary proteins (pronucleators) seem to be essential factors for cholesterol crystal formation and crystal growth in bile. A recent study suggests that fibronectin is such a pronucleator in bile.
Ritter, Christoph von +11 more
core +1 more source
Background Means to promote endogenous remyelination in multiple sclerosis (MS) benefit from insights into the role of inhibitory molecules that preclude remyelination.
Arend H. Sikkema +6 more
doaj +1 more source
Immunohistochemical localization of fibronectin as a tool for the age determination of human skin wounds [PDF]
We analyzed the distribution of fibronectin in routinely embedded tissue specimens from 53 skin wounds and 6 postmortem wounds. In postmortem wounds a faint but focal positive staining was exclusively found at the margin of the specimens which dit not ...
Penning, R. +13 more
core +1 more source

