Results 91 to 100 of about 354,159 (381)
Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro +12 more
wiley +1 more source
Inhibition of fibrous adhesion formation in the temporomandibular joint of tenascin-C knockout mice
European Journal of Histochemistry, 2014 Tenascin-C (TNC) is a large hexameric extracellular matrix glycoprotein that is expressed in developing organs and tumors. It has been reported that TNC is expressed in inflamed synovial membranes and deformed discs of temporomandibular joint (TMJ ...
Y. Shinohara +5 more
doaj +1 more source
Plasma and cellular fibronectin: distinct and independent functions during tissue repair
Fibrogenesis & Tissue Repair, 2011 Fibronectin (FN) is a ubiquitous extracellular matrix (ECM) glycoprotein that plays vital roles during tissue repair. The plasma form of FN circulates in the blood, and upon tissue injury, is incorporated into fibrin clots to exert effects on platelet ...
W. S. To, K. Midwood
semanticscholar +1 more source
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
Advanced Biology, EarlyView.This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim +3 more
wiley +1 more source
Frontiers in Bioengineering and Biotechnology, 2019 Fibronectin plays an essential role in tissue development and regeneration. However, the effects of fibronectin knockout (FN1-KO) on stem cells' proliferation and differentiation remain unknown.
Yiming Wang +8 more
doaj +1 more source
Journal of Cell Biology, 1989 We have investigated the effects of ligation of the fibronectin receptor (FnR) on gene expression in rabbit synovial fibroblasts. Monoclonal antibodies to the FnR that block initial adhesion of fibroblasts to fibronectin induced the expression of genes ...
Z. Werb +4 more
semanticscholar +1 more source
Tissue engineering a fetal membrane [PDF]
, 2011 The aim of this study was to construct an artificial fetal membrane (FM) by combination of human amniotic epithelial stem cells (hAESCs) and a mechanically enhanced collagen scaffold containing encapsulated human amniotic stromal fibroblasts (hASFs ...
Adam M. Squires +11 more
core +1 more source
Advanced Biology, EarlyView.Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang +6 more
wiley +1 more source
Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts
Respiratory Research, 2011 Background Bronchial fibroblasts contribute to airway remodelling, including airway wall fibrosis. Transforming growth factor (TGF)-β1 plays a major role in this process.
Ghavami Saeid +8 more
doaj +1 more source
Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells
Molecular Biology of the Cell, 2014 Aberrant accumulation of collagen IV defines diabetic nephropathy. It is shown here that high glucose increases fibronectin matrix assembly by activating integrin receptors on kidney cells.
Charles G. Miller +3 more
semanticscholar +1 more source