Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin+17 more
wiley +1 more source
Proliferative Anterior Optic Membranes in Hydrophobic Acrylic Intraocular Lenses
Kamran M Riaz,1 Blake L Williams,2 Steven G Safran,3 Mark J Gallardo4 1Department of Ophthalmology, Dean McGee Eye Institute/University of Oklahoma, Oklahoma City, OK, USA; 2Department of Ophthalmology and Visual Science, University of Chicago Medical ...
Riaz KM+3 more
doaj
Interaction of the 70,000-mol-wt amino-terminal fragment of fibronectin with the matrix-assembly receptor of fibroblasts. [PDF]
Paula J. McKeown‐Longo+1 more
openalex +1 more source
Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface. [PDF]
We investigated the role of the integrins alpha v beta 3 and alpha v beta 5 in mediating vitronectin adhesion of three phenotypically distinct cell types.
Cheresh, DA, Orlando, RA, Wayner, EA
core
Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases
This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu+16 more
wiley +1 more source
Electron microscopy and structural model of human fibronectin receptor. [PDF]
M. V. Nermut+4 more
openalex +1 more source
Biomimetic Dynamics of Nanoscale Groove and Ridge Topography for Stem Cell Regulation
Dynamic nanoscale groove‐ridge structures are engineered by flexibly conjugating RGD‐magnetic nanoparticles to nanogroove templates with variable groove widths at the molecular scale. Magnetic control enables cyclic switching between nanoscale groove and ridge states that modulates ligand accessibility of cellular integrins.
Hyunsik Hong+8 more
wiley +1 more source
Identification of fibronectin receptors on T lymphocytes. [PDF]
Pina M. Cardarelli+1 more
openalex +1 more source
Fibronectin on extracellular vesicles from microvascular endothelial cells is involved in the vesicle uptake into oligodendrocyte precursor cells. [PDF]
学位記番号 ...
Osawa, Sho+2 more
core