Results 171 to 180 of about 201,822 (256)

The pentose phosphate pathway contributes to excess lactate production in radiation-induced fibroblast to myofibroblast transdifferentiation. [PDF]

J Biol Chem
Pierre-Louis Odoom J, Camus SV, Sfeir M, Yue Y, Cowart LA, Freeberg MAT, Thatcher TH, Sime PJ.   +7 more
europepmc   +1 more source

Extracellular Vesicle‐Based Therapies for Osteoarthritis—Advances, Challenges and Hopes

Exploration, EarlyView.
Recent advances, challenges and hopes in using extracellular vesicles (EVs) as therapeutics for osteoarthritis. Recent advances include native and engineered EVs and translational developments. Challenges include cell sources and targeted effects of EVs, as well as establishing robust critical quality attributes, while hopes for advancing this field ...
Jiao Jiao Li, Wei Seong Toh
wiley   +1 more source

Silencing of USP22 promotes FGF11 degradation to attenuates renal fibrosis in diabetic kidney disease. [PDF]

Ren Fail
Wang Z, Liu C, Lv J, Sun J, Yu X, Li H.
europepmc   +1 more source

The importance of gene polymorphism in familial inheritance of endometriosis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The study aimed to investigate familial transmission patterns in women with endometriosis by generating a customized single‐nucleotide polymorphism (SNP) array. Methods Patients aged 18–45 who were diagnosed histopathologically with endometriosis were included in the study.
Hale Goksever Celik, Candan Eker, Berivan Guzelbag, Ercan Bastu, Tuba Gunel   +4 more
wiley   +1 more source

Development of a tissue-engineered oral mucosal barrier model using poly (L-lactic acid) electrospun nanofibers. [PDF]

Sci Rep
Sarasati A, Yucel D, Kenar H, Wihadmadyatami H, Ozdemir NS, Anggraeni R, Hasirci V, Ana ID.   +7 more
europepmc   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

Evaluation of ToF-SIMS imaging for semi-quantitative mapping of BODIPY-labeled fibronectin surface gradients.

Analyst
Liu C, Kim TKJ, Wu DH, Atit R, Somoza RA, Senyo SE.   +5 more
europepmc   +1 more source

Plexin A2 Knockdown Enhances Apoptosis in Chemotherapy Treated Melanoma Cells. [PDF]

Oncol Res
Palkina N, Esimbekova A, Lapkina E, Kutsenko V, Zinchenko I, Dereviankin E, Anisimova E, Savchenko A, Ruksha T.   +8 more
europepmc   +1 more source

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

iMetaOmics, EarlyView.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie, Jingyuan Ye, Sheng Wang, Maoyun Liu, Fengsheng Dai, Mingzhen Bai, Yi Wang, Athena Savoji, Yu Wang, Phillip B. Hylemon, Huiping Zhou, Hui Li, Dewei Li   +12 more
wiley   +1 more source

Silymarin attenuates diabetic nephropathy in rats via modulation of the miRNA-223/NLRP3/caspase-1/GSDMD axis and inflammasome-related pyroptotic signaling. [PDF]

Biol Direct
Aboismaiel MG, Amin MN, Eissa LA.
europepmc   +1 more source