Results 211 to 220 of about 247,327 (296)

Reticular Basement Membrane Remodelling Regulates Bronchial Epithelial Attachment, Barrier Integrity and Inflammatory Signalling in Asthma. [PDF]

Adv Respir Med
Hsieh A, Barker-Mulleder J, Yang CX, Fouadi M, Hackett TL.   +4 more
europepmc   +1 more source

Halogenated Tryptophans Improve Integrin αVβ6 Affinity of Cyclic RGD Peptides and Provide Handles for Late‐Stage Derivatization

Chemistry – A European Journal, EarlyView.
Lighting up αVβ6: Halotryptophan engineering converts an RGD scaffold into a modular αVβ6 ligand platform, enabling picomolar affinity and late‐stage functionalization. The resulting probes combine high selectivity with fluorescence for FACS and tumor imaging.
Beate Nachtigall, Caroline Brinkmann, Jana Langosch, Anke Nieß, Norbert Sewald   +4 more
wiley   +1 more source

Novel dermis niche equivalent based on a 3D-structure fabricated by 2-photon polymerization. [PDF]

Biomater Biosyst
Schröder S, Rothe H, Rehbein-Bode E, Heinrich D, Teusch N, Brandes N.   +5 more
europepmc   +1 more source

DNA Nanotechnology Meets Peptide and Protein Self‐Assembly

Chemistry – A European Journal, EarlyView.
Combining DNA nanotechnology with peptide and protein assembly provides complementary platforms for the rational engineering of functional biomaterials. This Perspective discusses the emerging field of self‐assembling DNA‐peptide and DNA‐protein hybrid systems that combine the structural precision and programmability of DNA nanotechnology with the ...
Marcel Hanke, Nanjundan Raghul, Adrian Keller, Veikko Linko, Verónica I. Dodero   +4 more
wiley   +1 more source

Silk Fibroin Peptides Promote Extracellular Matrix Homeostasis in Photoaging via Modulation of the ITGB1/FAK-TGF-β/Smad Signaling Axis. [PDF]

Molecules
He S, Yan Y, Xiong F, Diao W, Jia F, Yan X, Wang J.   +6 more
europepmc   +1 more source

Double Sided Traction Force Microscopy: A Method to Confine Cells for Physiologically Relevant Force Measurements

Cytoskeleton, EarlyView.
ABSTRACT In this paper we describe a technique to make a confined environment of variable stiffness that is suitable for high‐resolution live‐cell imaging. This versatile and adaptable technique enables cell confinement between soft elastic surfaces made from polyacrylamide gels.
Alexia Caillier, Patrick W. Oakes
wiley   +1 more source

A Novel <i>FN1</i> Nucleotide Variant c.3051G>C (p.Trp1017Cys) in a Pediatric Patient with Fibronectin Glomerulopathy: Case Report and Literature Review. [PDF]

J Clin Med
Sun L, Kuang X, Wu Y, Huang W.
europepmc   +1 more source

Talin1 Adhesion Morphology and Colocalization With Tensin3 Are Largely Unaffected by Polyacrylamide Substrate Stiffness

Cytoskeleton, EarlyView.
ABSTRACT Cells sense the stiffness of their extracellular matrix (ECM) and adapt their behavior accordingly. We investigated how ECM stiffness affects the spatial organization of talin1, a key mechanosensitive focal adhesion protein. Using polyacrylamide (PA) hydrogels with tunable stiffnesses (0.2–188 kPa), we analyzed cell morphology, migration ...
Joanna Hajduk, Patrycja Twardawa, Sylwia Bobis‐Wozowicz, Marta Szewczyk, Zenon Rajfur, Zbigniew Baster   +5 more
wiley   +1 more source

Matrix Gla Protein is a novel regulator of TGFβ-dependent fibroblast activation and kidney fibrosis. [PDF]

Mol Biomed
Barrera-Chimal J, López-Ramírez J, Henley N, Gao P, Ma Y, Desjardins-Lecavalier N, Costantino S, Royal V, Agten SM, Borrás T, Pichette V, Yuen DA, Schurgers LJ, Gerarduzzi C.   +13 more
europepmc   +1 more source