Results 81 to 90 of about 354,159 (381)

Vitronectin as a micromanager of cell response in material-driven fibronectin nanonetworks [PDF]

, 2017
Surface functionalization strategies of synthetic materials for regenerative medicine applications comprise the development of microenvironments that recapitulate the physical and biochemical cues of physiological extracellular matrices. In this context,
Altankov, Arima, Ballester-Beltran, Barrias, Barrère, Bathawab, Bornstein, Cantini, Chaturvedi, Crowder, Erickson, Erickson, Fabrizius-Homan, Felding-Habermann, Felgueiras, García, Gonzalez-Garcia, Guan, Guerra, Gugutkov, Gugutkov, Hinderer, Izumi, Kalaskar, Kamikubo, Keselowsky, Leahy, Leavesley, Llopis-Hernandez, Llopis-Hernández, Madsen, Malmstrom, Mao, Martino, Martino, Minor, Missirlis, Molnar, Nelea, Noh, Pankov, Pankov, Pearlstein, Podor, Pompe, Pompe, Preissner, Rico, Rico, Sabater, Salmeron-Sanchez, Salmeron-Sanchez, Schwarzbauer, Selinummi, Steele, Stockmann, Toromanov, Underwood, Vanterpool, Vaz, Vyner, Wilson, Wu, Xu, Yap, Zanetti, Zhang   +66 more
core   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Inflamed fibronectin: an altered fibronectin enhances neutrophil adhesion [PDF]

Blood, 1983
Recent investigations have emphasized the role of activated granulocytes in mediating vascular endothelial injury in the pathogenesis of shock lung. In vitro studies have indicated that tight adherence of the neutrophil to the endothelium is crucial for the development of cellular injury.
James B. McCarthy, Gregory M. Vercellotti, Leo T. Furcht, Harry S. Jacob, Charles F. Moldow   +4 more
openaire   +4 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

PRESENCE OF PLASMA AND CELLULAR FIBRONECTIN IN UTERINE SECRETIONS OF PIGS DURING EARLY PREGNANCY [PDF]

Journal of Central European Agriculture, 2007
The fibronectin is an extracellular matrix protein, which play a significant role in cell proliferation, differentiation and migration in several physiological and pathological processes.
PAVEL RASHEV
doaj  

Analysis of tissue transglutaminase function in the migration of swiss 3T3 fibroblasts - the active-state conformation of the enzyme does not affect cell motility but is important for its secretion [PDF]

, 2002
Increasing evidence suggests that tissue transglutaminase (tTGase; type II) is externalized from cells, where it may play a key role in cell attachment and spreading and in the stabilization of the extracellular matrix (ECM) through protein cross-linking.
Achyuthan, Aeschlimann, Aeschlimann, Akimov, Akiyama, Ball, Barsigian, Bowness, Bowness, Brown, Cai, Cariello, Di Venere, Fogerty, Folk, Freund, Gaudry, Gaudry, Gentile, Gossen, Griffin, Haroon, Isobe, Jackson, Jeong, Johnson, Johnson, Johnson, Jones, Laemmli, Lee, Lorand, Lowry, Martinez, Mian, Miyakawa, Palecek, Piotrowicz, Smethurst, Stewart, Tarantini, Upchurch, Verderio, Verderio, Weiss   +44 more
core   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

Matrix metalloproteinase 14 is required for fibrous tissue expansion

eLife, 2015
Type I collagen-containing fibrils are major structural components of the extracellular matrix of vertebrate tissues, especially tendon, but how they are formed is not fully understood.
Susan H Taylor, Ching-Yan Chloé Yeung, Nicholas S Kalson, Yinhui Lu, Paola Zigrino, Tobias Starborg, Stacey Warwood, David F Holmes, Elizabeth G Canty-Laird, Cornelia Mauch, Karl E Kadler   +10 more
doaj   +1 more source

Evidence that an RGD-dependent receptor mediates the binding of oligodendrocytes to a novel ligand in a glial-derived matrix. [PDF]

, 1988
A simple adhesion assay was used to measure the interaction between rat oligodendrocytes and various substrata, including a matrix secreted by glial cells. Oligodendrocytes bound to surfaces coated with fibronectin, vitronectin and a protein component of
Cardwell, MC, Rome, LH
core  

A crucial sequence for transglutaminase type 2 extracellular trafficking in renal tubular epithelial cells lies in its N-terminal {beta}-sandwich domain [PDF]

, 2011
Transglutaminase type 2 (TG2) catalyzes the formation of an -( -glutamyl)-lysine isopeptide bond between adjacent peptides or proteins including those of the extracellular matrix (ECM).
Chou, CY, Huang, L, Johnson, TS, Streets, AJ, Verderio, E, Watson, PF   +5 more
core   +1 more source