Results 21 to 30 of about 11,226 (256)

Phytophthora have distinct endogenous small RNA populations that include short interfering and microRNAs. [PDF]

PLoS ONE, 2013
In eukaryotes, RNA silencing pathways utilize 20-30-nucleotide small RNAs to regulate gene expression, specify and maintain chromatin structure, and repress viruses and mobile genetic elements.
Noah Fahlgren, Stephanie R Bollmann, Kristin D Kasschau, Josh T Cuperus, Caroline M Press, Christopher M Sullivan, Elisabeth J Chapman, J Steen Hoyer, Kerrigan B Gilbert, Niklaus J Grünwald, James C Carrington   +10 more
doaj   +1 more source

Pathophysiology of matrix metalloproteinases in breast cancer progression

Journal of Clinical and Scientific Research, 2019
Matrix metalloproteinases (MMPs) are secretary or membrane type proteolytic enzymes that act on extracellular matrix protein components such as collagens, gelatins, elastins, laminins, fibronectins, and integrins. MMPs are synthesized as zymogens and are
Sudheer Kumar Katari, Chiranjeevi Pasala, Ravina Madhulitha Nalamolu, Umakanth Naik Vankadoth, Sharon Priya Alexander, Siva Ranjani Pakala, Aparna R Bitla, Amineni Umamaheswari   +7 more
doaj   +1 more source

Characterization of a virulence-modifying protein of Leptospira interrogans identified by shotgun phage display

Frontiers in Microbiology, 2022
Pathogenic species of Leptospira are etiologic agents of leptospirosis, an emerging zoonotic disease of worldwide extent and endemic in tropical regions.
Fabiana Lauretti-Ferreira, Fabiana Lauretti-Ferreira, André Azevedo Reis Teixeira, Ricardo José Giordano, Josefa Bezerra da Silva, Patricia Antonia Estima Abreu, Angela Silva Barbosa, Milena Apetito Akamatsu, Paulo Lee Ho, Paulo Lee Ho   +9 more
doaj   +1 more source

Neural crest cell-autonomous roles of fibronectin in cardiovascular development. [PDF]

, 2015
The chemical and mechanical properties of extracellular matrices (ECMs) modulate diverse aspects of cellular fates; however, how regional heterogeneity in ECM composition regulates developmental programs is not well understood.
Astrof, Sophie, Wang, Xia
core   +2 more sources

Acellularization-Induced Changes in Tensile Properties Are Organ Specific - An In-Vitro Mechanical and Structural Analysis of Porcine Soft Tissues. [PDF]

PLoS ONE, 2016
INTRODUCTION:Though xenogeneic acellular scaffolds are frequently used for surgical reconstruction, knowledge of their mechanical properties is lacking. This study compared the mechanical, histological and ultrastructural properties of various native and
Stefan Schleifenbaum, Torsten Prietzel, Gabriela Aust, Andreas Boldt, Sebastian Fritsch, Isabel Keil, Holger Koch, Robert Möbius, Holger A Scheidt, Martin F X Wagner, Niels Hammer   +10 more
doaj   +1 more source

Microenvironment commits breast tumor ECs to dedifferentiation by micro-RNA-200-b-3p regulation and extracellular matrix remodeling

Frontiers in Cell and Developmental Biology, 2023
Introduction: Hypoxia shapes the tumor microenvironment, modulates distinct cell population activities, and activates pathological angiogenesis in cancer, where endothelial cells (ECs) are the most important players.
Kinga Wilkus-Adamczyk, Kinga Wilkus-Adamczyk, Klaudia Brodaczewska, Aleksandra Majewska, Aleksandra Majewska, Claudine Kieda, Claudine Kieda   +6 more
doaj   +1 more source

A Major Fraction of Fibronectin Present in the Extracellular Matrix of Tissues Is Plasma-derived [PDF]

, 2007
The origin of the fibronectin (FN) found in the extracellular matrix of tissues has not been defined experimentally. Previous studies suggest that there is contribution from both local tissue production and transfer from plasma, but the extent of this ...
Baralle, FE, Chauhan, AK, Iaconcig, A, Moretti, FA, Muro, AF, Porro, F   +5 more
core   +1 more source

Association of plasma fibronectin level with left atrial electrical and structural remodelling in lone paroxysmal atrial fibrillation: a cross-sectional study

Türk Kardiyoloji Derneği Arşivi, 2015
Objective: Atrial fibrosis is one of the main components of atrial fibrillation (AF) pathophysiology and culminates in structural, electrical and contractile remodelling. Fibronectin is one of the well-known mediators of fibrogenesis.
Uğur Canpolat, Ali Oto, Hikmet Yorgun, Hamza Sunman, Levent Şahiner, Ergün Barış Kaya, Necla Özer, Kudret Aytemir   +7 more
doaj   +1 more source

Endothelium-derived fibronectin regulates neonatal vascular morphogenesis in an autocrine fashion [PDF]

, 2017
Fibronectin containing alternatively spliced EIIIA and EIIIB domains is largely absent from mature quiescent vessels in adults, but is highly expressed around blood vessels during developmental and pathological angiogenesis.
Badu-Nkansah, Kwabena, Hynes, Richard O., Turner, Christopher   +2 more
core   +2 more sources

Immunohistochemical localization of fibronectin as a tool for the age determination of human skin wounds [PDF]

, 1992
We analyzed the distribution of fibronectin in routinely embedded tissue specimens from 53 skin wounds and 6 postmortem wounds. In postmortem wounds a faint but focal positive staining was exclusively found at the margin of the specimens which dit not ...
A Nerlich, A Vaheri, A. Nerlich, AE Postlethwaite, DF Mosher, E Boehm, E Linder, E Ruoslahti, E Ruoslahti, EA Jaffee, F Grinnell, F Grinnell, F Jilek, H Hormann, H Hormann, I. Wiest, J Raekallio, J Raekallio, J Viljanto, J. Tübel, J. Wilskel, K Alitalo, KM Yamada, LA Repesh, M Kurkinen, M Oehmichen, M Oehmichen, MW Mosesson, P Betz, P Davison, P. Betz, R Jarecki, R. Penning, RAF Clark, RAF Clark, S Berg, S Berg, S Berg, S Stenman, SM Hsu, St Niewiarowski, V Schneider, W Eisenmenger, W. Eisenmenger   +43 more
core   +1 more source