Results 21 to 30 of about 8,122 (251)

Microenvironment commits breast tumor ECs to dedifferentiation by micro-RNA-200-b-3p regulation and extracellular matrix remodeling

open access: yesFrontiers in Cell and Developmental Biology, 2023
Introduction: Hypoxia shapes the tumor microenvironment, modulates distinct cell population activities, and activates pathological angiogenesis in cancer, where endothelial cells (ECs) are the most important players.
Kinga Wilkus-Adamczyk   +6 more
doaj   +1 more source

Association of plasma fibronectin level with left atrial electrical and structural remodelling in lone paroxysmal atrial fibrillation: a cross-sectional study

open access: yesTürk Kardiyoloji Derneği Arşivi, 2015
Objective: Atrial fibrosis is one of the main components of atrial fibrillation (AF) pathophysiology and culminates in structural, electrical and contractile remodelling. Fibronectin is one of the well-known mediators of fibrogenesis.
Uğur Canpolat   +7 more
doaj   +1 more source

Acellularization-Induced Changes in Tensile Properties Are Organ Specific - An In-Vitro Mechanical and Structural Analysis of Porcine Soft Tissues. [PDF]

open access: yesPLoS ONE, 2016
INTRODUCTION:Though xenogeneic acellular scaffolds are frequently used for surgical reconstruction, knowledge of their mechanical properties is lacking. This study compared the mechanical, histological and ultrastructural properties of various native and
Stefan Schleifenbaum   +10 more
doaj   +1 more source

MD simulations and experiments of plasma proteins adsorption to the biodegradable magnesium alloys to facilitate cell response [PDF]

open access: yesarXiv, 2022
Once the magnesium alloy was implanted in the body, it was immediately covered with plasma proteins. The coated alloy surface promoted the adsorption and growth of osteoblasts. Herein, in vitro biological reactions of the ZK60 and AZ31 magnesium alloys were analyzed with and without plasma proteins incubation.
arxiv  

Studies of extracellular fibronectin matrix formation with fluoresceinated fibronectin and fibronectin fragments

open access: yesFEBS Letters, 1985
Fluorescein isothiocyanate conjugated human plasma fibronectin, 70‐kDa collagen‐binding, 60‐kDa central, 60‐kDa heparin‐binding, 180‐kDa heparin, collagen‐binding fibronectin fragments and gelatin were used to study extracellular fibronectin matrix formation.
M.L. Metsis   +2 more
openaire   +3 more sources

Protein Adsorption to Surface Chemistry and Crystal Structure Modification of Titanium Surfaces [PDF]

open access: yeseJournal of Oral Maxillofacial Research, 2010
Objectives: To observe the early adsorption of extracellular matrix and blood plasma proteins to magnesium-incorporated titanium oxide surfaces, which has shown superior bone response in animal models.Material and Methods: Commercially pure titanium ...
Ryo Jimbo   +4 more
doaj  

How cells tiptoe on adhesive surfaces before sticking [PDF]

open access: yesBiophysical Journal 94 (2008) 4114, 2008
Cell membranes are studded with protrusions that were thoroughly analyzed with electron microscopy. However, the nanometer-scale three-dimensional motions generated by cell membranes to fit the topography of foreign surfaces and initiate adhesion remain poorly understood.
arxiv   +1 more source

Central giant cell granuloma of the jaws and giant cell tumor of long bones: an immunohistochemical comparative study

open access: yesJournal of Applied Oral Science, 2007
OBJECTIVE: This study investigated whether some components of the extracellular matrix and CD68 expression may drive the differences between the central giant cell granuloma (CGCG) of the jaws and giant cell tumor (GCT) of long bones, which present ...
Maria do Socorro Aragão   +5 more
doaj   +1 more source

Interaction of heparin with fibronectin and isolated fibronectin domains [PDF]

open access: yesBiochemical Journal, 1990
Fluorescence polarization, gel exclusion chromatography and affinity chromatography were used to characterize the interaction of heparins of different size with human plasma fibronectin (Fn) and several of its isolated domains. The fluid-phase interaction of Fn with heparin was dominated by the 30 kDa and 40 kDa Hep-2 domains located near the C ...
Shelesa A. Brew   +2 more
openaire   +2 more sources

Matrix-immobilized BMP-2 on microcontact printed fibronectin as in vitro tool to study BMP-mediated signaling and cell migration

open access: yesFrontiers in Bioengineering and Biotechnology, 2015
During development, bone morphogenetic proteins (BMPs) exert important functions in several tissues by regulating signaling for cell differentiation and migration. In vivo the extracellular matrix (ECM) not only provides a support for adherent cells, but
Kristin eHauff   +11 more
doaj   +1 more source

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