Results 21 to 30 of about 8,122 (251)
Introduction: Hypoxia shapes the tumor microenvironment, modulates distinct cell population activities, and activates pathological angiogenesis in cancer, where endothelial cells (ECs) are the most important players.
Kinga Wilkus-Adamczyk+6 more
doaj +1 more source
Objective: Atrial fibrosis is one of the main components of atrial fibrillation (AF) pathophysiology and culminates in structural, electrical and contractile remodelling. Fibronectin is one of the well-known mediators of fibrogenesis.
Uğur Canpolat+7 more
doaj +1 more source
Acellularization-Induced Changes in Tensile Properties Are Organ Specific - An In-Vitro Mechanical and Structural Analysis of Porcine Soft Tissues. [PDF]
INTRODUCTION:Though xenogeneic acellular scaffolds are frequently used for surgical reconstruction, knowledge of their mechanical properties is lacking. This study compared the mechanical, histological and ultrastructural properties of various native and
Stefan Schleifenbaum+10 more
doaj +1 more source
MD simulations and experiments of plasma proteins adsorption to the biodegradable magnesium alloys to facilitate cell response [PDF]
Once the magnesium alloy was implanted in the body, it was immediately covered with plasma proteins. The coated alloy surface promoted the adsorption and growth of osteoblasts. Herein, in vitro biological reactions of the ZK60 and AZ31 magnesium alloys were analyzed with and without plasma proteins incubation.
arxiv
Fluorescein isothiocyanate conjugated human plasma fibronectin, 70‐kDa collagen‐binding, 60‐kDa central, 60‐kDa heparin‐binding, 180‐kDa heparin, collagen‐binding fibronectin fragments and gelatin were used to study extracellular fibronectin matrix formation.
M.L. Metsis+2 more
openaire +3 more sources
Protein Adsorption to Surface Chemistry and Crystal Structure Modification of Titanium Surfaces [PDF]
Objectives: To observe the early adsorption of extracellular matrix and blood plasma proteins to magnesium-incorporated titanium oxide surfaces, which has shown superior bone response in animal models.Material and Methods: Commercially pure titanium ...
Ryo Jimbo+4 more
doaj
How cells tiptoe on adhesive surfaces before sticking [PDF]
Cell membranes are studded with protrusions that were thoroughly analyzed with electron microscopy. However, the nanometer-scale three-dimensional motions generated by cell membranes to fit the topography of foreign surfaces and initiate adhesion remain poorly understood.
arxiv +1 more source
OBJECTIVE: This study investigated whether some components of the extracellular matrix and CD68 expression may drive the differences between the central giant cell granuloma (CGCG) of the jaws and giant cell tumor (GCT) of long bones, which present ...
Maria do Socorro Aragão+5 more
doaj +1 more source
Interaction of heparin with fibronectin and isolated fibronectin domains [PDF]
Fluorescence polarization, gel exclusion chromatography and affinity chromatography were used to characterize the interaction of heparins of different size with human plasma fibronectin (Fn) and several of its isolated domains. The fluid-phase interaction of Fn with heparin was dominated by the 30 kDa and 40 kDa Hep-2 domains located near the C ...
Shelesa A. Brew+2 more
openaire +2 more sources
During development, bone morphogenetic proteins (BMPs) exert important functions in several tissues by regulating signaling for cell differentiation and migration. In vivo the extracellular matrix (ECM) not only provides a support for adherent cells, but
Kristin eHauff+11 more
doaj +1 more source