Results 11 to 20 of about 8,605 (201)

Inside Out Integrin Activation Mediated by PIEZO1 Signaling in Erythroblasts

Frontiers in Physiology, 2020
The non-selective mechanosensitive ion channel PIEZO1 controls erythrocyte volume homeostasis. Different missense gain-of-function mutations in PIEZO1 gene have been identified that cause Hereditary Xerocytosis (HX), a rare autosomal dominant haemolytic ...
Francesca Aglialoro, Naomi Hofsink, Menno Hofman, Nicole Brandhorst, Emile van den Akker   +4 more
doaj   +1 more source

Edema de Reinke: estudo da imunoexpressão da fibronectina, da laminina e do colágeno IV em 60 casos por meio de técnicas imunoistoquímicas Reinkes'edema: immunoexpression study of fibronectin, laminin and colagen IV in 60 cases by imunohistochemical techniques

Brazilian Journal of Otorhinolaryngology, 2009
Edema de Reinke é doença crônica da laringe na qual a camada superficial da lâmina própria é expandida por muco espesso conferindo-lhe aspecto gelatinoso.
Regina Helena Garcia Martins, Maria Aparecida Domingues, Alexandre Todorovic Fabro, Norimar Hernandes Dias, Marcela Ferreira Santana   +4 more
doaj   +1 more source

Phytophthora have distinct endogenous small RNA populations that include short interfering and microRNAs. [PDF]

PLoS ONE, 2013
In eukaryotes, RNA silencing pathways utilize 20-30-nucleotide small RNAs to regulate gene expression, specify and maintain chromatin structure, and repress viruses and mobile genetic elements.
Noah Fahlgren, Stephanie R Bollmann, Kristin D Kasschau, Josh T Cuperus, Caroline M Press, Christopher M Sullivan, Elisabeth J Chapman, J Steen Hoyer, Kerrigan B Gilbert, Niklaus J Grünwald, James C Carrington   +10 more
doaj   +1 more source

Pathophysiology of matrix metalloproteinases in breast cancer progression

Journal of Clinical and Scientific Research, 2019
Matrix metalloproteinases (MMPs) are secretary or membrane type proteolytic enzymes that act on extracellular matrix protein components such as collagens, gelatins, elastins, laminins, fibronectins, and integrins. MMPs are synthesized as zymogens and are
Sudheer Kumar Katari, Chiranjeevi Pasala, Ravina Madhulitha Nalamolu, Umakanth Naik Vankadoth, Sharon Priya Alexander, Siva Ranjani Pakala, Aparna R Bitla, Amineni Umamaheswari   +7 more
doaj   +1 more source

Characterization of a virulence-modifying protein of Leptospira interrogans identified by shotgun phage display

Frontiers in Microbiology, 2022
Pathogenic species of Leptospira are etiologic agents of leptospirosis, an emerging zoonotic disease of worldwide extent and endemic in tropical regions.
Fabiana Lauretti-Ferreira, Fabiana Lauretti-Ferreira, André Azevedo Reis Teixeira, Ricardo José Giordano, Josefa Bezerra da Silva, Patricia Antonia Estima Abreu, Angela Silva Barbosa, Milena Apetito Akamatsu, Paulo Lee Ho, Paulo Lee Ho   +9 more
doaj   +1 more source

Acellularization-Induced Changes in Tensile Properties Are Organ Specific - An In-Vitro Mechanical and Structural Analysis of Porcine Soft Tissues. [PDF]

PLoS ONE, 2016
INTRODUCTION:Though xenogeneic acellular scaffolds are frequently used for surgical reconstruction, knowledge of their mechanical properties is lacking. This study compared the mechanical, histological and ultrastructural properties of various native and
Stefan Schleifenbaum, Torsten Prietzel, Gabriela Aust, Andreas Boldt, Sebastian Fritsch, Isabel Keil, Holger Koch, Robert Möbius, Holger A Scheidt, Martin F X Wagner, Niels Hammer   +10 more
doaj   +1 more source

Microenvironment commits breast tumor ECs to dedifferentiation by micro-RNA-200-b-3p regulation and extracellular matrix remodeling

Frontiers in Cell and Developmental Biology, 2023
Introduction: Hypoxia shapes the tumor microenvironment, modulates distinct cell population activities, and activates pathological angiogenesis in cancer, where endothelial cells (ECs) are the most important players.
Kinga Wilkus-Adamczyk, Kinga Wilkus-Adamczyk, Klaudia Brodaczewska, Aleksandra Majewska, Aleksandra Majewska, Claudine Kieda, Claudine Kieda   +6 more
doaj   +1 more source

Association of plasma fibronectin level with left atrial electrical and structural remodelling in lone paroxysmal atrial fibrillation: a cross-sectional study

Türk Kardiyoloji Derneği Arşivi, 2015
Objective: Atrial fibrosis is one of the main components of atrial fibrillation (AF) pathophysiology and culminates in structural, electrical and contractile remodelling. Fibronectin is one of the well-known mediators of fibrogenesis.
Uğur Canpolat, Ali Oto, Hikmet Yorgun, Hamza Sunman, Levent Şahiner, Ergün Barış Kaya, Necla Özer, Kudret Aytemir   +7 more
doaj   +1 more source

Matrix-immobilized BMP-2 on microcontact printed fibronectin as in vitro tool to study BMP-mediated signaling and cell migration

Frontiers in Bioengineering and Biotechnology, 2015
During development, bone morphogenetic proteins (BMPs) exert important functions in several tissues by regulating signaling for cell differentiation and migration. In vivo the extracellular matrix (ECM) not only provides a support for adherent cells, but
Kristin eHauff, Kristin eHauff, Chiara eZambarda, Chiara eZambarda, Miriam eDietrich, Maria eHalbig, Maria eHalbig, Anna Luise Grab, Rebecca eMedda, Rebecca eMedda, Elisabetta Ada eCavalcanti-Adam, Elisabetta Ada eCavalcanti-Adam   +11 more
doaj   +1 more source

Central giant cell granuloma of the jaws and giant cell tumor of long bones: an immunohistochemical comparative study

Journal of Applied Oral Science, 2007
OBJECTIVE: This study investigated whether some components of the extracellular matrix and CD68 expression may drive the differences between the central giant cell granuloma (CGCG) of the jaws and giant cell tumor (GCT) of long bones, which present ...
Maria do Socorro Aragão, Marta Rabello Piva, Cassiano Francisco Weege Nonaka, Roseana de Almeida Freitas, Lélia Batista de Souza, Leão Pereira Pinto   +5 more
doaj   +1 more source