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Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue sarcoma with aggressive local behavior but with a low metastatic potential. Although slow growing and indolent, they rarely reach huge sizes. Very uncommonly, these locally invasive tumors undergo fibrosarcomatous transformation with a more aggressive clinical course, with higher rate of ...
Manisha Aggarwal +6 more
openaire +2 more sources
Vulvar Darier-Ferrand dermatofibrosarcoma: unusual localization of a rare tumor
Dermatofibrosarcoma protuberans (DFSP) is a low-to-intermediate grade sarcoma of dermal origin that rarely presents in the vulva, typically occurring on the trunk of young to middle-aged adults.
Ines Zemni +6 more
doaj +1 more source
PDGFD‐Rearranged Dermatofibrosarcoma Protuberans With S100 and Pan‐TRK Expression
ABSTRACT Dermatofibrosarcoma protuberans (DFSP) is a fibroblastic malignancy characterized in most cases by COL1A1::PDGFB fusion. Rare cases exhibit alternative rearrangements involving PDGFD. Here, we describe a female patient in her third decade of life who presented with a spindle cell proliferation on the shoulder.
Venezia Podesta +4 more
wiley +1 more source
The Technologies for African Agricultural Transformation (TAAT) Program was initiated by the African Development Bank (AfDB) as part of its Feed Africa Initiative.
Technologies for African Agricultural Transformation
core +1 more source
Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
Journal of Cutaneous Immunology and Allergy, Volume 6, Issue 4, Page 117-119, August 2023.
wiley +1 more source
Dermatofibrosarcoma protuberans (DFSP) is a relatively rare, locally aggressive, and dermal-based fibroblastic tumor. There are several histological variants, in which the usual emphasis is on fibrosarcomatous DFSP, as it acquires metastatic potential ...
Shui-ying Cheng +5 more
core +1 more source
Absence of PD-L1 Protein Expression in Classic Dermatofibrosarcoma Protuberans
Background: This study aimed to assess the prevalence of PD-L1 protein expression in dermatofibrosarcoma protuberans (DFSP) to provide insights into the potential use of immune checkpoint inhibitors.
Thilo Gambichler +3 more
doaj +1 more source
Bifocal metachronous dermato fibrosarcoma protuberans in children: A case report
Key Clinical Message Dermato fibrosarcoma protuberans presents challenges in diagnosis and treatment, especially in children. Awareness of its aggressive local recurrence and its potential for multifocal presentation is crucial. Wide surgical resection with adequate margins remains the basis of management, in association with regular follow‐up of ...
Wajdi Arfa +6 more
wiley +1 more source
Dermatofibrosarcoma protuberans
Introduction: Dermatofibrosarcoma protuberans (DFSP) is an uncommon skin tumor with a low-to-intermediate grade of malignancy, characterized by progressive growth and a propensity for local recurrence. In this series, we are analyzing the clinicopathological spectrum of DFSP cases.
Sakshi, Dahiya +6 more
openaire +2 more sources

