Results 11 to 20 of about 493 (122)
Cross‐talk between CFTR and sphingolipids in cystic fibrosis
FEBS Open Bio, Volume 13, Issue 9, Page 1601-1614, September 2023., 2023 Several lines of evidence shown that in cystic fibrosis the lack of the cystic fibrosis transmembrane conductance regulator (CFTR) is accompanied by changes in the plasma membrane composition of a bioactive class of lipids known as sphingolipids. Here, we depict a general overview of the literature related to the impact of the modifications of the ...
Dorina Dobi +6 more
wiley +1 more source
Towards Targeting the Aryl Hydrocarbon Receptor in Cystic Fibrosis
Mediators of Inflammation, Volume 2018, Issue 1, 2018., 2018 Tryptophan (trp) metabolism is an important regulatory component of gut mucosal homeostasis and the microbiome. Metabolic pathways targeting the trp can lead to a myriad of metabolites, of both host and microbial origins, some of which act as endogenous low‐affinity ligands for the aryl hydrocarbon receptor (AhR), a cytosolic, ligand‐operated ...
Matteo Puccetti +13 more
wiley +1 more source
The Mast Cell‐Aryl Hydrocarbon Receptor Interplay at the Host‐Microbe Interface
Mediators of Inflammation, Volume 2018, Issue 1, 2018., 2018 Mast cells are increasingly being recognized as crucial cells in the response of the organism to environmental agents. Interestingly, the ability of mast cells to sense and respond to external cues is modulated by the microenvironment that surrounds mast cells and influences their differentiation.
Claudio Costantini +13 more
wiley +1 more source
Mediators of Inflammation, Volume 2017, Issue 1, 2017., 2017 Cystic fibrosis (CF) is the most common autosomal genetic recessive disease caused by mutations of gene encoding for the cystic fibrosis transmembrane conductance regulator. Patients with CF display a wide spectrum of symptoms, the most severe being chronic lung infection and inflammation, which lead to onset of cystic fibrosis lung disease.
Domitilla Schiumarini +14 more
wiley +1 more source
Mediators of Inflammation, Volume 2017, Issue 1, 2017., 2017 The angelicin analogue 4,6,4′‐trimethylangelicin (TMA) was recently reported as a strong inhibitor of nuclear factor‐κB (NF‐κB) activity and of the expression of the interleukin‐8 (IL‐8) gene in bronchial epithelial cells in which the inflammatory response has been challenged with P.
Ilaria Lampronti +14 more
wiley +1 more source
Immunology &Cell Biology, Volume 92, Issue 8, Page 659-670, September 2014., 2014 Unlike induced Foxp3+ regulatory T cells (Foxp3+ iTreg) that have been shown to play an essential role in the development of protective immunity to the ubiquitous mold Aspergillus fumigatus, type‐(1)‐regulatory T cells (Tr1) cells have, thus far, not been implicated in this process.
Tanja Bedke +9 more
wiley +1 more source
Brazilian Journal of Otorhinolaryngology, 2010 Embora o perfil das citocinas na polipose nasossinusal seja bem documentado, pouco se sabe sobre estas proteínas quando associadas à Fibrose Cística. OBJETIVOS: Avaliar a expressão das citocinas IL¬4, IL¬5, IL¬6, IL¬8, GM¬C-SF e IFN--y analisada pela RT¬-
Flávio Barbosa Nunes +6 more
doaj +1 more source
Prática fisioterapêutica no tratamento da fibrose cística
ABCS Health Sciences, 2014 A fibrose cística (FC), denominada também de mucoviscidose, é uma doença genética do tipo autossômica recessiva que acomete principalmente crianças e indivíduos de raça branca.
Carolina Lazzarim de Conto +6 more
doaj +1 more source
Protein Science, Volume 34, Issue 10, October 2025.Abstract The outer membrane (OM) of Gram‐negative bacteria is an asymmetric bilayer composed of glycerophospholipids (GPLs) in the inner leaflet and lipopolysaccharide in the outer leaflet, which is critical for viability and antibiotic resistance.
Davide Sposato +9 more
wiley +1 more source
Demetra, 2014 Objetivo: Tecer considerações acerca de possíveis contribuições da visita domiciliar de nutrição como estratégia de acompanhamento da terapia nutricional em adultos com fibrose cística.
Vangelina Lins Melo +2 more
doaj +1 more source