Screening for cystic fibrosis by measurement of unstimulated parotid saliva sodium levels. [PDF]
D. Lawson+2 more
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This study explores the role of gemcitabine (GEM)‐resistant pancreatic cancer‐derived extracellular vesicles (EVs) in activating pancreatic stellate cells (PSCs) and promoting extracellular matrix production. GEM‐resistant cells release higher levels of asparagine (Asn), which triggers PSC activation. Long noncoding RNA sequencing identified linc‐ZNF25‐
Miao Yu+6 more
wiley +1 more source
Combined mediastinal and retroperitoneal fibrosis [PDF]
Howard W. Salmon
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The Fe3O4/Gd@BSA‐pPB nanoprobe leverages biomimetic mineralization and targets hepatic stellate cells (HSCs) through PDGFRβ, offering superior enrichment in fibrotic regions. This targeted delivery overcomes biological barriers, enhancing both the accuracy and sensitivity of MRI imaging at early disease stages.
Zehua Li+11 more
wiley +1 more source
Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis. [PDF]
Jirouskova M+9 more
europepmc +1 more source
Side-effects to antibiotics in cystic fibrosis. I: ocular changes in relation to antibiotic administration and to severity of pulmonary involvement. [PDF]
C G Keith+2 more
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In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao+19 more
wiley +1 more source
Association and mediation between circulating inflammatory proteins and skin fibrosis. [PDF]
Zhao Z+8 more
europepmc +1 more source
ADAR1‐HNRNPL‐Mediated CircCANX Decline Promotes Autophagy in Chronic Obstructive Pulmonary Disease
ADAR1‐HNRNPL interaction‐repressed circCANX recruits P53 mRNA and UPF1 to assemble a complex in nuclear. This complex promotes P53 mRNA degradation through the NMD pathway, and finally reduces autophagy and stress granules formation to further regulate inflammation.
Ting‐Ting Chen+10 more
wiley +1 more source
Inhibition of Rho GEFs attenuates pulmonary fibrosis through suppressing myofibroblast activation and reprogramming profibrotic macrophages. [PDF]
Luo C+8 more
europepmc +1 more source