Results 31 to 40 of about 858,069 (214)
Research progress on multiple cell death pathways of podocytes in diabetic kidney disease
Molecular Medicine, 2023 Diabetic kidney disease (DKD) is the main cause of end-stage renal disease, and its clinical manifestations are progressive proteinuria, decreased glomerular filtration rate, and renal failure. The injury and death of glomerular podocytes are the keys to
Can Yang +7 more
doaj +1 more source
Genome-wide DNA methylation dynamics in carbon tetrachloride-induced mice liver fibrosis [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Many persistent harmful stimuli can result in chronic liver diseases, which lead to about 2 million deaths per year in the whole world. Liver fibrosis was found to exist in all kinds of chronic liver diseases.
Deming Li +5 more
doaj +1 more source
Clinical Case Reports, 2022 This study summarizes efficacy of ivacaftor treatment in 2 infants in a real‐world setting. A distinct decline of sweat chloride and lung clearance index plus increase in fecal elastase was seen. The results underline the early and sustainable effect and
Teresa Fuchs +3 more
doaj +1 more source
Molecular Therapy: Nucleic AcidsNonsense or premature termination codon (PTC) variants of the CFTR gene are pathogenic and found in ∼10% of North American people with cystic fibrosis.
Normand E. Allaire +15 more
doaj +1 more source
Clinics in Chest Medicine, 2006 Pleural fibrosis can result from a variety of inflammatory processes. The response of the pleural mesothelial cell to injury and the ability to maintain its integrity are crucial in determining whether normal healing or pleural fibrosis occurs.
Division of Pulmonary and Critical Care Medicine, University of Florida SW Archer Road, Room M352, PO Box 100225, Gainesville, FL 32610–0225, USA ( host institution ) +2 more
openaire +3 more sources
Elevated sweat chloride test: is it always cystic fibrosis?
Italian Journal of Pediatrics, 2021 Background The sweat chloride test (ST) is the gold standard for cystic fibrosis (CF) diagnosis in symptomatic patients, within the newborn screening and in the follow-up of CF patients during molecular therapies.
C. Cimbalo +6 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2011 IntroductionOrganisms of the Burkholderia cepacia complex (BCC) are important pathogens in cystic fibrosis (CF). The majority of those who acquire BCC develop chronic infection but it can also result in rapid decline in a significant minority.
Alex eHorsley +7 more
doaj +1 more source
Validating the Data Completeness and Accuracy of the Canadian Cystic Fibrosis Registry
Canadian Respiratory JournalConclusion: Our validation of the CCFR demonstrated high accuracy for clinical and demographic variables used in clinical research.
Ranjani Somayaji +9 more
doaj +1 more source
How are the ancient cystic fibrosis patients? Cystic fibrosis diagnosed over 60 years-old
Respiratory Medicine Case Reports, 2017 Background and aims: To specify the prevalence of patients diagnosed with CF at age of ≥60 year-old and to analyze their characteristics. Patients and methods: Observational study of CF patients which were diagnosed at age ≥60 year-old.
C. Prados +10 more
doaj +1 more source
Six minute walk test in Italian children with cystic fibrosis aged 6 and 11
Monaldi Archives for Chest Disease, 2021 Six Minute Walk Test (6MWT) is a field exercise test widely used in clinical practice, both in adults and in pediatric patients. The primary aim of the study is to evaluate the physical performance of the subjects and compare them with the predicted ...
Diletta Innocenti +11 more
doaj +1 more source