Results 31 to 40 of about 5,382 (190)

Fibrinogen-related proteins in ixodid ticks [PDF]

open access: yes, 2011
Background Fibrinogen-related proteins with lectin activity are believed to be part of the tick innate immune system. Several fibrinogen-related proteins have been described and characterised mainly on the basis of their cDNA sequences while direct ...
Jan Sterba   +4 more
core   +2 more sources

Ficolin-2 amplifies inflammation in macrophage-smooth muscle cell cross-talk and increases monocyte transmigration by mechanisms involving IL-1β and IL-6

open access: yesScientific Reports, 2023
Ficolin-2, recently identified in atherosclerotic plaques, has been correlated with future acute cardiovascular events, but its role remains unknown. We hypothesize that it could influence plaque vulnerability by interfering in the cross-talk between ...
Răzvan Daniel Macarie   +5 more
doaj   +1 more source

Antimicrobial peptides and complement in neonatal hypoxia-ischemia induced brain damage [PDF]

open access: yes, 2015
Hypoxic-ischemic encephalopathy (HIE) is a clinical condition in the neonate, resulting from oxygen deprivation around the time of birth. HIE affects 1-5/1000 live births worldwide and is associated with the development of neurological deficits ...
Hristova, M, Rocha-Ferreira, E
core   +1 more source

Allelic lineages of the ficolin genes (FCNs) are passed from ancestral to descendant primates.

open access: yesPLoS ONE, 2011
The ficolins recognize carbohydrates and acetylated compounds on microorganisms and dying host cells and are able to activate the lectin pathway of the complement system.
Tina Hummelshøj   +5 more
doaj   +1 more source

Proteomic analysis of mare follicular fluid during late follicle development [PDF]

open access: yes, 2010
Background: Follicular fluid accumulates into the antrum of follicle from the early stage of follicle development. Studies on its components may contribute to a better understanding of the mechanisms underlying follicular development and oocyte quality ...
Jean-Louis Dacheux   +4 more
core   +4 more sources

AmpliSeq screening of genes encoding the C-Type lectin receptors and their signaling components reveals a common variant in MASP1 associated with pulmonary tuberculosis in an Indian population [PDF]

open access: yes, 2018
Tuberculosis (TB) is a multifactorial disease governed by bacterial, host and environmental factors. On the host side, growing evidence shows the crucial role that genetic variants play in the susceptibility to Mycobacterium tuberculosis (Mtb) infection.
Abid Hussain   +14 more
core   +6 more sources

Collectins and ficolins in neonatal health and disease

open access: yesFrontiers in Immunology, 2023
The immune system starts to develop early in embryogenesis. However, at birth it is still immature and associated with high susceptibility to infection.
Maciej Cedzyński, Anna S. Świerzko
doaj   +1 more source

Ficolin-1–PTX3 Complex Formation Promotes Clearance of Altered Self-Cells and Modulates IL-8 Production [PDF]

open access: yesThe Journal of Immunology, 2013
Abstract The long pentraxin 3 (PTX3) has been shown to be important in maintaining internal tissue homeostasis and in protecting against fungal Aspergillus fumigatus infection. However, the molecular mechanisms of how these functions are elicited are poorly delineated.
Ma, Ying Jie   +6 more
openaire   +4 more sources

The pattern-recognition molecule H-ficolin in relation to diabetic kidney disease, mortality, and cardiovascular events in type 1 diabetes

open access: yesScientific Reports, 2021
H-ficolin recognizes patterns on microorganisms and stressed cells and can activate the lectin pathway of the complement system. We aimed to assess H-ficolin in relation to the progression of diabetic kidney disease (DKD), all-cause mortality, diabetes ...
Jakob Appel Østergaard   +9 more
doaj   +1 more source

A large-scale plasma proteome Mendelian randomization study identifies novel causal plasma proteins related to primary biliary cholangitis

open access: yesFrontiers in Immunology, 2023
Background and aimsPrimary biliary cholangitis (PBC) is a progressive chronic autoimmune cholestatic liver disease characterized by the destruction of small intrahepatic bile ducts leading to biliary cirrhosis.
Hongqun Yang, Lanlan Chen, Yahui Liu
doaj   +1 more source

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