Results 111 to 120 of about 5,472 (201)

Complement factors C4 and C3 are down regulated in response to short term overfeeding in healthy young men [PDF]

, 2017
Insulin resistance is associated with high circulating level of complement factor C3. Animal studies suggest that improper complement activation mediates high-fat-diet-induced insulin resistance.
Brøns, Charlotte, Foghmar, Caroline, Garred, Peter, Pilely, Katrine, Vaag, Allan   +4 more
core   +1 more source

Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin–Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H–Related Protein-5 (FHR5) Deposition

Kidney International Reports, 2018
IgA nephropathy (IgAN) is characterized by glomerular deposition of galactose-deficient IgA1 and complement proteins and leads to renal impairment. Complement deposition through the alternative and lectin activation pathways is associated with renal ...
Nicholas R. Medjeral-Thomas, Anne Troldborg, Nicholas Constantinou, Hannah J. Lomax-Browne, Annette G. Hansen, Michelle Willicombe, Charles D. Pusey, H. Terence Cook, Steffen Thiel, Matthew C. Pickering   +9 more
doaj   +1 more source

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population

Frontiers in Immunology, 2018
Introduction: The complement system is essential for an adequate immune response. Much attention has been given to the role of complement in disease. However, to better understand complement in pathology, it is crucial to first analyze this system under ...
Mariana Gaya da Costa, Felix Poppelaars, Felix Poppelaars, Cees van Kooten, Tom E. Mollnes, Tom E. Mollnes, Tom E. Mollnes, Francesco Tedesco, Reinhard Würzner, Leendert A. Trouw, Leendert A. Trouw, Lennart Truedsson, Mohamed R. Daha, Mohamed R. Daha, Anja Roos, Marc A. Seelen   +15 more
doaj   +1 more source

Serum Levels of Ficolin-3 and Mannose-Binding Lectin in Patients with Leprosy and Their Family Contacts in a Hyperendemic Region in Northeastern Brazil. [PDF]

Trop Med Infect Dis, 2022
Oliveira FJF, Serra MAAO, Santos LHD, Araújo MFM, Silva RNCD, Grumach AS.   +5 more
europepmc   +1 more source

Lectin Pathway of Complement Activation Is Associated with Vulnerability of Atherosclerotic Plaques [PDF]

, 2017
Inflammatory mechanisms may be involved in atherosclerotic plaque rupture. By using a novel histology-based method to quantify plaque instability here, we assess whether lectin pathway (LP) of complement activation, a major inflammation arm, could ...
De Blasio, Daiana, De Nigris, Francesca, De Simoni, Maria-Grazia, Ferrante, Angela M R, Fumagalli, Stefano, Garred, Peter, Oggioni, Marco, Perego, Carlo, Snider, Francesco, Zangari, Rosalia   +9 more
core   +2 more sources

Utilization of Whole Exome Sequencing in Non-Syndromic Premature Ovarian Failure: Ficolin-3 Gene Mutation in an Iranian Family [PDF]

Iran Biomed J, 2021
Mehrjooy S, Nikbakht R, Mohammadi Asl J, Ghadiri A, Ghandil P.   +4 more
europepmc   +1 more source

Association of ficolin-1 and ficolin-3 gene variation and pulmonary tuberculosis susceptibility in a Chinese population. [PDF]

J Clin Lab Anal, 2021
Li Y, You EQ, Lin WH, Liu XN, Shen DP, Zhang XL, Ma DC, Li HM.   +7 more
europepmc   +1 more source

Complement Profiles in Patients with Amyotrophic Lateral Sclerosis: A Prospective Observational Cohort Study

Journal of Inflammation Research, 2021
Anne-Lene Kjældgaard,1,2 Katrine Pilely,1 Karsten Skovgaard Olsen,2 Anne Øberg Lauritsen,2 Stephen Wørlich Pedersen,3 Kirsten Svenstrup,3,4 Merete Karlsborg,4 Helle Thagesen,5 Morten Blaabjerg,5 Ásta Theódórsd ...
Kjældgaard AL, Pilely K, Olsen KS, Øberg Lauritsen A, Wørlich Pedersen S, Svenstrup K, Karlsborg M, Thagesen H, Blaabjerg M, Theódórsdóttir Á, Gundtoft Elmo E, Torvin Møller A, Pedersen NA, Kirkegaard N, Møller K, Garred P   +15 more
doaj  

Localized-statistical quantification of human serum proteome associated with type 2 diabetes.

PLoS ONE, 2008
BackgroundRecent advances in proteomics have shed light to discover serum proteins or peptides as biomarkers for tracking the progression of diabetes as well as understanding molecular mechanisms of the disease.ResultsIn this work, human serum of non ...
Rong-Xia Li, Hai-Bing Chen, Kang Tu, Shi-Lin Zhao, Hu Zhou, Su-Jun Li, Jie Dai, Qing-Run Li, Song Nie, Yi-Xue Li, Wei-Ping Jia, Rong Zeng, Jia-Rui Wu   +12 more
doaj   +1 more source

Pattern Recognition Molecules of Lectin Complement Pathway in Ischemic Stroke

Pharmacogenomics and Personalized Medicine, 2021
Gohar Tsakanova,1,2 Ani Stepanyan,1 Rudi Steffensen,3 Armine Soghoyan,4 Jens Christian Jensenius,5 Arsen Arakelyan1 1Institute of Molecular Biology NAS RA, Yerevan, Armenia; 2CANDLE Synchrotron Research Institute, Yerevan, Armenia; 3Department of ...
Tsakanova G, Stepanyan A, Steffensen R, Soghoyan A, Jensenius JC, Arakelyan A   +5 more
doaj