Results 91 to 100 of about 5,472 (201)

Reduced Dietary Protein Induces Changes in the Dental Proteome

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 2, Page 107-127, March 2026.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs, Christopher J. Percival, Natasha S. Vitek   +2 more
wiley   +1 more source

Towards identification of novel putative biomarkers for infective endocarditis by serum proteomic analysis [PDF]

, 2020
Introduction: Infective endocarditis (IE) has high mortality, partly due to delayed diagnosis. No biomarker can identify IE in patients with fever and clinical picture of infection.
Honoré, Bent, Ludvigsen, Maja, Petersen, Eskild, Poulsen, Steen Hvitfeldt, Rasmussen, Lars Melholt, Snipsøyr, Magnus Giske, Stensballe, Allan, Vorum, Henrik, Wiggers, Henrik   +8 more
core   +2 more sources

Translational Systems Pharmacology Studies in Pregnant Women [PDF]

, 2017
Pregnancy involves rapid physiological adaptation and complex interplay between mother and fetus. New analytic technologies provide large amounts of genomic, proteomic, and metabolomics data.
Gullapelli, Rakesh, Haas, David M., Quinney, Sara K.   +2 more
core   +1 more source

Complement Hyperactivation Is Mediated by Alternative and Lectin Pathways During Early Phase of Severe Vaccination‐Omicron BA.5 Infection

Journal of Medical Virology, Volume 98, Issue 3, March 2026.
ABSTRACT Complement temporal activation kinetics, activation pathways, and their relationship with thromboinflammation and antibody responses in severe vaccination‐COVID‐19 remains unclear. Based on a vaccinated‐infected cohort, we analyzed complement immune responses across mild to critical COVID‐19 cases by a dynamic model.
Jinpeng Cao, Gang Yang, Tingting Cui, Jian Qin, Deyi Huang, Shiqin Jin, Xiaoyun Yang, Mingzhu Huang, Xiaoling Su, Siyi Liu, Yingjiao Xia, Shidong Deng, Chengna Luo, Zhuxiang Zhao, Yunhui Zhang, Nanshan Zhong, Zhongfang Wang   +16 more
wiley   +1 more source

Exploring complement biomarkers in suspected axial spondyloarthritis

RMD Open
Objectives To investigate lectin pathway proteins (LPPs) as biomarkers for axial spondyloarthritis (axSpA) in a cross-sectional cohort with a suspicion of axSpA, comprising newly diagnosed axSpA and chronic low back pain (cLBP) individuals.Methods Serum ...
Joachim Sieper, Denis Poddubnyy, Anne Gitte Loft, Anne Troldborg, Fabian Proft, Mikhail Protopopov, Valeria Rios Rodriguez, Judith Rademacher, Steffen Thiel, Burkhard Muche, Susanne Lüders, Laura Spiller, Anne-Katrin Weber, Clara Elbæk Mistegård   +13 more
doaj   +1 more source

Early Changes of Mannose-Binding Lectin, H-Ficolin, and Procalcitonin in Patients with Febrile Neutropenia: A Prospective Observational Study

Turkish Journal of Hematology, 2016
Objective: The significance of mannose-binding lectin (MBL) and H-ficolin deficiency in febrile neutropenic (FN) patients and the correlation of these markers along with consecutive C-reactive protein (CRP) and procalcitonin (PCT) levels during the ...
Sibel Işlak Mutcalı, Neşe Saltoğlu, İlker İnanç Balkan, Reşat Özaras, Mücahit Yemişen, Bilgül Mete, Fehmi Tabak, Ali Mert, Recep Öztürk, Şeniz Öngören, Zafer Başlar, Yıldız Aydın, Burhan Ferhanoğlu, Teoman Soysal   +13 more
doaj   +1 more source

P13 Acquired ficolin-3 deficiency in patients with systemic lupus erythematosus

Lupus Science and Medicine
, Elisabet Svenungsson, Iva Gunnarsson, Lars Rönnblom, Andreas Jönsen, Christopher Sjöwall, Solbritt Rantapää-Dahlqvist, Dag Leonard, Johanna K Sandling, Anders A Bengtsson, Bo Nilsson, Helena Enocsson, Matteo Bianchi, Kerstin Lindblad-Toh, Sergey V Kozyrev, Lina-Marcela Diaz-Gallo, Christian Lundtoft, Ahmed Sayadi, Linnea Lindelöf, Mun-Gwan Hong, Kristina Nilsson Ekdahl, Oskar Eriksson   +21 more
doaj   +2 more sources

Classical and lectin complement pathways and markers of inflammation for investigation of susceptibility to infections among healthy older adults

Immunity & Ageing, 2020
Background There is increasing recognition of the significance of chronic, low-level inflammation in older adults, or “inflammaging.” Innate immune responses and host-bacterial interactions are recognized as key factors in inflammaging.
David C. LaFon, Steffen Thiel, Young-il Kim, Mark T. Dransfield, Moon H. Nahm   +4 more
doaj   +1 more source

Expression of human ficolin-2 in hepatocytes confers resistance to infection by diverse hepatotropic viruses [PDF]

, 2019
The liver-expressed pattern recognition receptors (PRRs) mannose binding lectin (MBL), ficolin-2 and ficolin-3 contribute to the innate immune response by activating complement.
Ball, Jonathan K., Goddard, Chun, Horncastle, Emma, Irving, William L., Jalal, Paywast J., King, Barnabas J., Mason, Christopher P., McClure, C. Patrick, Pathak, Monika, Saeed, Amanj, Tarr, Alexander W., Urbanowicz, Richard A.   +11 more
core   +2 more sources

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

Advanced Science, Volume 13, Issue 10, 18 February 2026.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin, Jovanne Palvair, Lennie Messager, Jamal Bamoulid, Jasper Callemeyn, Mélanie Chaintreuil, Ludivine Dal Zuffo, Didier Ducloux, Imane Farhat, Mathieu Legendre, Laurent Martin, Florian Renosi, Xavier Roussel, Thibaut Vaulet, Maarten Naesens, Claire Tinel, Baptiste Lamarthée   +16 more
wiley   +1 more source